SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t81'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 7 LEU A 125
VAL A 119
LEU A 430
LEU A 198
 None
 0.78A 1cqpA-5t81A:
undetectable
1cqpB-5t81A:
undetectable		 1cqpA-5t81A:
14.45
1cqpB-5t81A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 TYR A 235
GLY A  79
PHE A  72
LEU A 130
ALA A 127
 None
 1.38A 1e3vA-5t81A:
undetectable		 1e3vA-5t81A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.30A 1fk9A-5t81A:
3.4		 1fk9A-5t81A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 GLY A 313
LEU A 338
HIS A 450
LEU A 486
TYR A 482
 None
 1.46A 1fm6D-5t81A:
undetectable		 1fm6D-5t81A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.44A 1ikwA-5t81A:
3.2		 1ikwA-5t81A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 11 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.44A 1jkhA-5t81A:
3.4
1jkhB-5t81A:
3.3		 1jkhA-5t81A:
22.30
1jkhB-5t81A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.40A 1lw0A-5t81A:
3.7		 1lw0A-5t81A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 11 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.42A 1lwcA-5t81A:
2.1		 1lwcA-5t81A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 TYR A 482
LEU A 448
ILE A 315
HIS A 287
LEU A 479
 None
 1.26A 1tw4B-5t81A:
undetectable		 1tw4B-5t81A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 GLY A 313
LEU A 338
HIS A 450
LEU A 486
TYR A 482
 None
 1.49A 1zgyA-5t81A:
undetectable		 1zgyA-5t81A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 11 GLY A  84
GLY A  87
GLN A 445
THR A  90
ILE A  95
 None
 1.42A 2dr2A-5t81A:
undetectable		 2dr2A-5t81A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.43A 2hndA-5t81A:
3.9		 2hndA-5t81A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.43A 2hnyA-5t81A:
undetectable		 2hnyA-5t81A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 5t81 EPOB
(Sorangium
cellulosum) 		3 / 3 LEU A 271
PRO A 272
ARG A 286
 None
 0.64A 2qd4B-5t81A:
undetectable		 2qd4B-5t81A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 TYR A 101
ARG A  99
GLN A 431
HIS A 287
 None
 1.19A 2vxaA-5t81A:
undetectable
2vxaC-5t81A:
undetectable
2vxaE-5t81A:
undetectable		 2vxaA-5t81A:
8.21
2vxaC-5t81A:
8.21
2vxaE-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 GLN A 431
TYR A 101
ARG A  99
HIS A 287
 None
 1.21A 2vxaA-5t81A:
undetectable
2vxaB-5t81A:
undetectable
2vxaK-5t81A:
undetectable		 2vxaA-5t81A:
8.21
2vxaB-5t81A:
8.21
2vxaK-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 GLN A 431
TYR A 101
ARG A  99
HIS A 287
 None
 1.21A 2vxaB-5t81A:
undetectable
2vxaC-5t81A:
undetectable
2vxaG-5t81A:
undetectable		 2vxaB-5t81A:
8.21
2vxaC-5t81A:
8.21
2vxaG-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 TYR A 101
ARG A  99
GLN A 431
HIS A 287
 None
 1.20A 2vxaD-5t81A:
undetectable
2vxaF-5t81A:
undetectable
2vxaI-5t81A:
undetectable		 2vxaD-5t81A:
8.21
2vxaF-5t81A:
8.21
2vxaI-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 GLN A 431
TYR A 101
ARG A  99
HIS A 287
 None
 1.20A 2vxaD-5t81A:
undetectable
2vxaE-5t81A:
undetectable
2vxaL-5t81A:
undetectable		 2vxaD-5t81A:
8.21
2vxaE-5t81A:
8.21
2vxaL-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 HIS A 287
TYR A 101
ARG A  99
GLN A 431
 None
 1.21A 2vxaF-5t81A:
undetectable
2vxaG-5t81A:
undetectable
2vxaI-5t81A:
undetectable		 2vxaF-5t81A:
8.21
2vxaG-5t81A:
8.21
2vxaI-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 HIS A 287
GLN A 431
TYR A 101
ARG A  99
 None
 1.20A 2vxaB-5t81A:
undetectable
2vxaG-5t81A:
undetectable
2vxaH-5t81A:
undetectable		 2vxaB-5t81A:
8.21
2vxaG-5t81A:
8.21
2vxaH-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 GLN A 431
TYR A 101
ARG A  99
HIS A 287
 None
 1.21A 2vxaH-5t81A:
undetectable
2vxaI-5t81A:
undetectable
2vxaJ-5t81A:
undetectable		 2vxaH-5t81A:
8.21
2vxaI-5t81A:
8.21
2vxaJ-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 HIS A 287
TYR A 101
ARG A  99
GLN A 431
 None
 1.21A 2vxaD-5t81A:
undetectable
2vxaJ-5t81A:
undetectable
2vxaL-5t81A:
undetectable		 2vxaD-5t81A:
8.21
2vxaJ-5t81A:
8.21
2vxaL-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 HIS A 287
GLN A 431
TYR A 101
ARG A  99
 None
 1.21A 2vxaH-5t81A:
undetectable
2vxaJ-5t81A:
undetectable
2vxaK-5t81A:
undetectable		 2vxaH-5t81A:
8.21
2vxaJ-5t81A:
8.21
2vxaK-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 8 HIS A 287
GLN A 431
TYR A 101
ARG A  99
 None
 1.22A 2vxaA-5t81A:
undetectable
2vxaK-5t81A:
undetectable
2vxaL-5t81A:
undetectable		 2vxaA-5t81A:
8.21
2vxaK-5t81A:
8.21
2vxaL-5t81A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 430
LEU A 198
VAL A 184
ILE A 213
PHE A 115
 None
 1.07A 2w9gA-5t81A:
undetectable		 2w9gA-5t81A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 9 ASP A 464
VAL A 466
ILE A 283
GLY A  94
ILE A  95
 None
 1.26A 3el4B-5t81A:
undetectable		 3el4B-5t81A:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 ASP A 464
VAL A 466
ILE A 283
GLY A  94
ILE A  95
 None
 1.16A 3el5A-5t81A:
undetectable		 3el5A-5t81A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 LEU A 430
LEU A 198
VAL A 184
ILE A 213
PHE A 115
 None
 1.05A 3fl9B-5t81A:
undetectable		 3fl9B-5t81A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 430
LEU A 198
VAL A 184
ILE A 213
PHE A 115
 None
 1.14A 3fl9E-5t81A:
undetectable		 3fl9E-5t81A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 LEU A 430
LEU A 198
VAL A 184
ILE A 213
PHE A 115
 None
 1.04A 3fl9G-5t81A:
undetectable		 3fl9G-5t81A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 11 LEU A 430
LEU A 198
VAL A 184
ILE A 213
PHE A 115
 None
 1.00A 3frbX-5t81A:
undetectable		 3frbX-5t81A:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 9 LEU A 430
LEU A 198
VAL A 184
ILE A 213
PHE A 115
 None
 0.96A 3freX-5t81A:
undetectable		 3freX-5t81A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 5t81 EPOB
(Sorangium
cellulosum) 		3 / 3 ARG A 172
ILE A 203
THR A 352
 None
 0.66A 3ia4D-5t81A:
undetectable		 3ia4D-5t81A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 4 PRO A 444
TYR A  81
GLY A  84
THR A  86
 None
 1.01A 3ib0A-5t81A:
undetectable		 3ib0A-5t81A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 ILE A 145
ALA A 143
LEU A 125
LEU A 430
VAL A 184
 None
 1.05A 3ix9B-5t81A:
undetectable		 3ix9B-5t81A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 6 ILE A 145
VAL A 184
LEU A 198
LEU A 430
 None
 0.84A 3kp6A-5t81A:
undetectable
3kp6B-5t81A:
undetectable		 3kp6A-5t81A:
15.82
3kp6B-5t81A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.43A 3qipA-5t81A:
3.5		 3qipA-5t81A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 7 LEU A 459
TYR A 453
TYR A 482
HIS A 450
 None
 1.31A 4arcA-5t81A:
undetectable		 4arcA-5t81A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_A_PARA500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 PHE A 339
SER A 211
ASP A 216
TYR A 235
GLY A 353
 None
 1.49A 4qb9A-5t81A:
undetectable		 4qb9A-5t81A:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 6 ILE A 203
GLN A  78
ILE A 394
ASP A  76
 None
 1.18A 4w5qA-5t81A:
undetectable		 4w5qA-5t81A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 5 ASP A 276
VAL A 466
PHE A 470
GLY A 468
 None
 1.26A 4xp6A-5t81A:
undetectable		 4xp6A-5t81A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 HIS A 183
VAL A 197
VAL A 185
LEU A 165
ALA A 168
 None
 1.30A 4yhaA-5t81A:
undetectable		 4yhaA-5t81A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 HIS A 183
VAL A 197
VAL A 185
LEU A 165
ALA A 168
 None
 1.29A 4yhaG-5t81A:
undetectable		 4yhaG-5t81A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5t81 EPOB
(Sorangium
cellulosum) 		4 / 6 ILE A 203
GLN A  78
ILE A 394
ASP A  76
 None
 1.17A 4z4cA-5t81A:
undetectable		 4z4cA-5t81A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 5t81 EPOB
(Sorangium
cellulosum) 		3 / 3 LYS A 117
ARG A 121
HIS A 122
 None
 1.08A 4zbrA-5t81A:
undetectable		 4zbrA-5t81A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 HIS A 183
VAL A 197
VAL A 185
LEU A 165
ALA A 168
 None
 1.30A 5tt3C-5t81A:
undetectable		 5tt3C-5t81A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 9 HIS A 183
VAL A 197
VAL A 185
LEU A 165
ALA A 168
 None
 1.41A 5tt3E-5t81A:
undetectable		 5tt3E-5t81A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 ILE A 351
PHE A 355
LEU A 240
ALA A 241
LEU A 242
 None
 1.17A 5y7pD-5t81A:
undetectable		 5y7pD-5t81A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 LEU A 474
LYS A 274
VAL A 469
GLY A 468
LEU A 271
 None
 1.45A 6bsiA-5t81A:
2.1		 6bsiA-5t81A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 VAL A 108
LEU A 111
GLY A 434
LEU A 433
THR A 194
 None
 1.30A 6czmE-5t81A:
undetectable
6czmF-5t81A:
1.6		 6czmE-5t81A:
20.88
6czmF-5t81A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		3 / 3 GLU A 159
LEU A 162
ARG A 166
 None
 0.64A 6d8fA-5t81A:
undetectable		 6d8fA-5t81A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 12 VAL A 205
ASP A 206
LEU A 218
ASP A 216
LEU A 430
 None
 0.81A 6ew0F-5t81A:
undetectable		 6ew0F-5t81A:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 11 TYR A  98
ASP A 464
THR A 441
HIS A 171
ASP A 467
 None
 1.34A 6mb5A-5t81A:
undetectable		 6mb5A-5t81A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 TYR A  98
ASP A 464
THR A 441
HIS A 171
ASP A 467
 None
 1.37A 6mb9A-5t81A:
undetectable		 6mb9A-5t81A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 TYR A  98
ASP A 464
THR A 441
HIS A 171
ASP A 467
 None
 1.36A 6mb9B-5t81A:
undetectable		 6mb9B-5t81A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 TYR A  98
ASP A 464
THR A 441
HIS A 171
ASP A 467
 None
 1.36A 6mb9C-5t81A:
undetectable		 6mb9C-5t81A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 5t81 EPOB
(Sorangium
cellulosum) 		5 / 10 TYR A  98
ASP A 464
THR A 441
HIS A 171
ASP A 467
 None
 1.39A 6mb9D-5t81A:
undetectable		 6mb9D-5t81A:
11.03