SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA888_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 5t86 CDIA TOXIN
CDII IMMUNITY
PROTEIN
(Escherichia
coli;
Escherichia
coli) 		4 / 5 PRO A 212
LYS I  37
ALA A 189
GLU A 247
 None
 1.22A 1qhsA-5t86A:
undetectable		 1qhsA-5t86A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5t86 CDIA TOXIN
CDII IMMUNITY
PROTEIN
(Escherichia
coli;
Escherichia
coli) 		4 / 6 PRO A 212
LYS I  37
ALA A 189
GLU A 247
 None
 1.36A 1qhyA-5t86A:
undetectable		 1qhyA-5t86A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5t86 CDII IMMUNITY
PROTEIN
(Escherichia
coli) 		5 / 11 ILE I  90
ASP I  54
PHE I  53
ASN I  82
ILE I  86
 None
 0.89A 2blaA-5t86I:
undetectable		 2blaA-5t86I:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 5t86 CDIA TOXIN
CDII IMMUNITY
PROTEIN
(Escherichia
coli) 		4 / 6 ASP A 177
LEU A 174
ASP A 201
LEU I   3
 None
None
ACT  A 304 (-3.0A)
None
 1.02A 3bj8C-5t86A:
undetectable
3bj8D-5t86A:
undetectable		 3bj8C-5t86A:
21.56
3bj8D-5t86A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5t86 CDIA TOXIN
CDII IMMUNITY
PROTEIN
(Escherichia
coli;
Escherichia
coli) 		3 / 3 PHE I 113
ASP I  72
ARG A 207
 None
 0.90A 4eahF-5t86I:
undetectable		 4eahF-5t86I:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5t86 CDIA TOXIN
CDII IMMUNITY
PROTEIN
(Escherichia
coli;
Escherichia
coli) 		3 / 3 PHE I 113
ASP I  72
ARG A 207
 None
 0.89A 4eahG-5t86I:
undetectable		 4eahG-5t86I:
17.77