SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5t87 CDII IMMUNITY
PROTEIN
(Cupriavidus
taiwanensis) 		4 / 5 LEU A  89
PHE A  46
VAL A  67
ALA A 105
 None
 1.22A 2cizA-5t87A:
undetectable		 2cizA-5t87A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_B_CHDB1_0
(FERROCHELATASE)		 5t87 CDII IMMUNITY
PROTEIN
CDIA TOXIN
(Cupriavidus
taiwanensis;
Cupriavidus
taiwanensis) 		5 / 10 MET E 225
LEU E 221
ARG A  75
SER E 180
GLY E 213
 None
 1.41A 2qd2B-5t87E:
undetectable		 2qd2B-5t87E:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 5t87 CDIA TOXIN
CDII IMMUNITY
PROTEIN
(Cupriavidus
taiwanensis) 		3 / 3 PRO E 170
GLU E 178
TYR A   5
 None
 0.79A 2zmbA-5t87E:
undetectable		 2zmbA-5t87E:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5t87 CDII IMMUNITY
PROTEIN
CDIA TOXIN
(Cupriavidus
taiwanensis;
Cupriavidus
taiwanensis) 		5 / 7 MET E 225
LEU E 221
ARG A  75
SER E 180
GLY E 213
 None
 1.46A 3hcnA-5t87E:
undetectable		 3hcnA-5t87E:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5t87 CDII IMMUNITY
PROTEIN
CDIA TOXIN
(Cupriavidus
taiwanensis;
Cupriavidus
taiwanensis) 		5 / 9 MET E 225
LEU E 221
ARG A  75
SER E 180
GLY E 213
 None
 1.46A 3hcnB-5t87E:
undetectable		 3hcnB-5t87E:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5t87 CDII IMMUNITY
PROTEIN
CDIA TOXIN
(Cupriavidus
taiwanensis;
Cupriavidus
taiwanensis) 		5 / 9 MET E 225
LEU E 221
ARG A  75
SER E 180
GLY E 213
 None
 1.49A 3hcoA-5t87E:
undetectable		 3hcoA-5t87E:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5t87 CDII IMMUNITY
PROTEIN
CDIA TOXIN
(Cupriavidus
taiwanensis;
Cupriavidus
taiwanensis) 		5 / 10 MET E 225
LEU E 221
ARG A  75
SER E 180
GLY E 213
 None
 1.49A 3hcpB-5t87E:
undetectable		 3hcpB-5t87E:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5t87 CDII IMMUNITY
PROTEIN
(Cupriavidus
taiwanensis) 		4 / 8 SER A  22
GLY A  23
ILE A  35
SER A  34
 None
 0.82A 5alcL-5t87A:
undetectable		 5alcL-5t87A:
17.81