SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		5 / 12 ARG X 261
GLY X 316
PRO X 257
THR X 256
ILE X 229
 None
 0.99A 1c6zA-5t89X:
undetectable		 1c6zA-5t89X:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		3 / 3 ARG X 546
ILE X 464
TRP X 466
 None
 1.17A 1qomA-5t89X:
undetectable		 1qomA-5t89X:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		3 / 3 HIS X 214
ASP X 130
ASN X 100
 None
None
NAG  X 701 (-1.9A)
 0.79A 1wg8B-5t89X:
undetectable		 1wg8B-5t89X:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		4 / 5 PRO X 470
ILE X 529
GLY X 531
TYR X 533
 None
 1.10A 2jkjD-5t89X:
undetectable		 2jkjD-5t89X:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		4 / 5 PRO X 470
ILE X 529
GLY X 531
TYR X 533
 None
 1.10A 2jkjF-5t89X:
undetectable		 2jkjF-5t89X:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		5 / 12 GLU X 137
TYR X 220
THR X 222
LEU X 205
LEU X 169
 None
 1.19A 2mjiA-5t89X:
1.1		 2mjiA-5t89X:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		4 / 6 THR X 643
ARG X 637
LEU X 583
ASP X 586
 None
 0.95A 2wm3A-5t89X:
undetectable		 2wm3A-5t89X:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		3 / 3 ARG X 546
ILE X 464
TRP X 466
 None
 1.00A 3nw2A-5t89X:
undetectable		 3nw2A-5t89X:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		3 / 3 ARG X 546
ILE X 464
TRP X 466
 None
 1.13A 3nw2B-5t89X:
undetectable		 3nw2B-5t89X:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		5 / 11 ARG X 261
GLY X 316
PRO X 257
THR X 256
ILE X 229
 None
 0.91A 4njvB-5t89X:
undetectable		 4njvB-5t89X:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		5 / 11 ARG X 261
GLY X 316
PRO X 257
THR X 256
ILE X 229
 None
 0.96A 4njvC-5t89X:
undetectable		 4njvC-5t89X:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1
(Homo
sapiens) 		5 / 12 ARG X 261
GLY X 316
PRO X 257
THR X 256
ILE X 229
 None
 0.93A 4njvD-5t89X:
undetectable		 4njvD-5t89X:
10.34