SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 11 ILE A 370
ASP A 386
LEU A 382
PHE A 381
VAL A 434
None
None
None
EDO  A 907 (-3.6A)
None
1.37A 1axwB-5t98A:
undetectable
1axwB-5t98A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 GLY A 109
GLY A 190
PHE A 107
GLY A 192
None
0.74A 1d0vA-5t98A:
undetectable
1d0vA-5t98A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FMJ_B_RTLB501_0
(RETINOL DEHYDRATASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 10 TYR A 548
TYR A 655
LEU A 641
SER A 547
MET A 365
None
1.37A 1fmjB-5t98A:
0.0
1fmjB-5t98A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 VAL A 128
VAL A 197
ILE A 160
LEU A  84
None
0.84A 1iepB-5t98A:
undetectable
1iepB-5t98A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 GLY A 109
GLY A 190
PHE A 107
GLY A 192
None
0.72A 1jhaA-5t98A:
undetectable
1jhaA-5t98A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 4 HIS A 431
ASP A 467
SER A 472
ASP A 428
None
1.47A 1n2xA-5t98A:
1.7
1n2xA-5t98A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 6 PHE A 476
ASN A 497
ILE A 443
GLY A 440
None
1.09A 1oniD-5t98A:
undetectable
1oniF-5t98A:
undetectable
1oniD-5t98A:
11.57
1oniF-5t98A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 ILE A 443
GLY A 440
PHE A 476
ASN A 497
None
0.87A 1oniG-5t98A:
undetectable
1oniI-5t98A:
undetectable
1oniG-5t98A:
11.57
1oniI-5t98A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 VAL A 434
ASP A 386
ASP A 383
LEU A 424
None
1.11A 1pk2A-5t98A:
undetectable
1pk2A-5t98A:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 GLY A 517
THR A 473
ILE A 493
GLY A 495
None
0.84A 1usqA-5t98A:
undetectable
1usqA-5t98A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 GLY A 517
THR A 473
ILE A 493
GLY A 495
None
0.83A 2jklA-5t98A:
undetectable
2jklA-5t98A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 GLY A 517
THR A 473
ILE A 493
GLY A 495
None
0.83A 2jklC-5t98A:
3.6
2jklC-5t98A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 GLY A 517
THR A 473
ILE A 493
GLY A 495
None
0.85A 2jklD-5t98A:
undetectable
2jklD-5t98A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 GLY A 517
THR A 473
ILE A 493
GLY A 495
None
0.86A 2jklF-5t98A:
undetectable
2jklF-5t98A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
0.97A 2obvA-5t98A:
undetectable
2obvA-5t98A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 11 ASN A 441
GLU A 442
TYR A 498
GLU A 519
TRP A 578
TRS  A 909 (-3.9A)
EDO  A 908 ( 2.7A)
None
TRS  A 909 (-2.6A)
TRS  A 909 (-3.5A)
0.75A 2v3dB-5t98A:
15.2
2v3dB-5t98A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 TYR A 557
TYR A 628
ILE A 577
None
0.83A 3eteA-5t98A:
undetectable
3eteB-5t98A:
undetectable
3eteA-5t98A:
20.63
3eteB-5t98A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 LYS A 677
ILE A 577
PHE A 576
None
0.96A 3j7zS-5t98A:
undetectable
3j7za-5t98A:
undetectable
3j7zS-5t98A:
8.54
3j7za-5t98A:
2.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 11 GLU A  65
ALA A 135
LEU A 178
THR A 110
THR A 179
None
1.14A 3mdzA-5t98A:
undetectable
3mdzA-5t98A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 PHE A 787
ILE A 762
LEU A 776
THR A 797
None
0.95A 3nxuA-5t98A:
undetectable
3nxuA-5t98A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 ILE A 244
GLY A 211
THR A 297
LEU A 295
GLY A 271
None
1.08A 3uq6B-5t98A:
undetectable
3uq6B-5t98A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 ILE A 244
GLY A 211
THR A 297
LEU A 295
GLY A 271
None
1.09A 3vaqB-5t98A:
undetectable
3vaqB-5t98A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 LYS A 502
LYS A 499
PRO A 500
None
1.19A 4dv1L-5t98A:
undetectable
4dv1L-5t98A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
0.98A 4kttA-5t98A:
undetectable
4kttA-5t98A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
0.98A 4kttC-5t98A:
undetectable
4kttC-5t98A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 ASP A 582
TRP A 632
SER A 525
None
0.97A 4lrhA-5t98A:
undetectable
4lrhA-5t98A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 LEU A 776
ARG A 806
MET A 346
None
0.94A 4m11C-5t98A:
undetectable
4m11C-5t98A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 5 VAL A 654
LEU A 713
ILE A 640
LEU A 641
None
0.77A 4mghA-5t98A:
undetectable
4mghA-5t98A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.00A 4ndnA-5t98A:
undetectable
4ndnA-5t98A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
0.95A 4ndnC-5t98A:
undetectable
4ndnC-5t98A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.06A 4odjA-5t98A:
undetectable
4odjA-5t98A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 GLU A 209
ASP A 202
ASP A 161
LEU A 199
GLY A 131
None
1.41A 4pgfB-5t98A:
undetectable
4pgfB-5t98A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 THR A 473
VAL A 491
THR A 372
ILE A 435
TYR A 516
None
None
EDO  A 907 (-4.5A)
None
None
1.34A 4s0vA-5t98A:
undetectable
4s0vA-5t98A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.03A 5a1iA-5t98A:
undetectable
5a1iA-5t98A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.03A 5a1iA-5t98A:
undetectable
5a1iA-5t98A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 GLY A 791
GLY A 793
THR A 797
ARG A 527
ILE A 816
None
1.06A 5bw4A-5t98A:
undetectable
5bw4A-5t98A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 ASP A  87
ASN A 351
PHE A 381
None
None
EDO  A 907 (-3.6A)
0.76A 5dsgB-5t98A:
undetectable
5dsgB-5t98A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 THR A 156
PRO A 376
ASP A 394
None
0.85A 5l8dB-5t98A:
undetectable
5l8dB-5t98A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 THR A 156
PRO A 376
ASP A 394
None
0.85A 5mwuB-5t98A:
undetectable
5mwuB-5t98A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 VAL A 615
ASP A 582
LEU A 769
ARG A 357
GLY A 791
None
1.24A 5syeB-5t98A:
undetectable
5syeB-5t98A:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 ARG A 316
GLN A 287
VAL A 392
ASP A 467
EDO  A 904 ( 4.6A)
None
None
None
1.14A 5vlmF-5t98A:
undetectable
5vlmF-5t98A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 PHE A 581
GLY A 619
VAL A 790
GLY A 613
ALA A 795
None
1.08A 6c2mA-5t98A:
undetectable
6c2mA-5t98A:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
5 / 12 PHE A 581
GLY A 619
VAL A 790
GLY A 613
ALA A 795
None
1.01A 6c2mB-5t98A:
undetectable
6c2mB-5t98A:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 ARG A  60
ARG A 114
ASP A  76
None
0.84A 6d8pA-5t98A:
undetectable
6d8pA-5t98A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
0.99A 6fbnB-5t98A:
undetectable
6fbnB-5t98A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.03A 6fboA-5t98A:
undetectable
6fboA-5t98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.10A 6fcbA-5t98A:
undetectable
6fcbA-5t98A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 8 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.03A 6fcdA-5t98A:
undetectable
6fcdA-5t98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
3 / 3 THR A 658
ALA A 663
LYS A 674
None
0.76A 6fgdA-5t98A:
undetectable
6fgdA-5t98A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 6 ASP A 398
ARG A 371
GLN A 446
LYS A 404
None
1.42A 6g31L-5t98A:
undetectable
6g31L-5t98A:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
5t98 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis)
4 / 7 PRO A 559
ASP A 560
SER A 703
ASP A 549
None
1.05A 6g6rA-5t98A:
undetectable
6g6rA-5t98A:
20.24