SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 GLY A  79
THR A 586
LEU A 389
ASP A 386
 None
 0.82A 1aegA-5t9gA:
undetectable		 1aegA-5t9gA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 GLU A 794
LEU A 802
TYR A 804
GLY A  82
ALA A 595
 None
 1.24A 1httC-5t9gA:
undetectable		 1httC-5t9gA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 PHE A 378
TYR A 119
TYR A 403
GLY A 132
SER A 134
 None
 1.13A 1igxA-5t9gA:
undetectable		 1igxA-5t9gA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 TYR A 114
PHE A 128
TYR A 131
PRO A 130
 None
 1.38A 1mclA-5t9gA:
5.2
1mclB-5t9gA:
4.9
1mclP-5t9gA:
undetectable		 1mclA-5t9gA:
14.22
1mclB-5t9gA:
14.22
1mclP-5t9gA:
1.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 6 TRP A 657
ASN A 553
LEU A 554
PHE A 460
 GIF  A 901 ( 4.4A)
None
None
None
 1.06A 1ru9H-5t9gA:
5.8
1ru9L-5t9gA:
5.1		 1ru9H-5t9gA:
12.13
1ru9L-5t9gA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 6 TRP A 657
ASN A 553
LEU A 554
PHE A 460
 GIF  A 901 ( 4.4A)
None
None
None
 1.08A 1rukH-5t9gA:
5.9
1rukL-5t9gA:
6.3		 1rukH-5t9gA:
12.13
1rukL-5t9gA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 LEU A 308
PHE A 573
ARG A 503
ILE A 298
PHE A 306
 None
 1.48A 1skxA-5t9gA:
undetectable		 1skxA-5t9gA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 10 ILE A 433
ALA A 493
ILE A 485
ILE A 437
TYR A 520
 None
 1.38A 2dm6A-5t9gA:
undetectable
2dm6B-5t9gA:
undetectable		 2dm6A-5t9gA:
18.04
2dm6B-5t9gA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 GLU A 583
ASN A 390
TYR A 459
GLU A 436
ARG A 352
 GIF  A 901 (-2.9A)
GIF  A 901 (-3.7A)
None
GIF  A 901 (-2.9A)
None
 1.39A 2f0zA-5t9gA:
undetectable		 2f0zA-5t9gA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 SER A 171
GLY A  86
HIS A 321
ASP A 164
 None
 1.08A 2oxtB-5t9gA:
undetectable		 2oxtB-5t9gA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 11 ASN A 435
GLU A 436
TYR A 531
GLU A 552
TRP A 575
 GIF  A 901 ( 4.0A)
GIF  A 901 (-2.9A)
None
GIF  A 901 (-2.8A)
GIF  A 901 (-4.0A)
 0.69A 2v3dB-5t9gA:
14.4		 2v3dB-5t9gA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASN A 553
ALA A 350
LEU A 343
GLY A 577
 None
 0.88A 3dl9A-5t9gA:
undetectable		 3dl9A-5t9gA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASN A 424
THR A 288
SER A 277
SER A 227
 None
 1.26A 3hlwB-5t9gA:
undetectable		 3hlwB-5t9gA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ILE A 108
PHE A 110
ASP A 111
GLU A 176
 None
None
EDO  A 904 (-3.5A)
None
 0.93A 3kp6A-5t9gA:
undetectable
3kp6B-5t9gA:
undetectable		 3kp6A-5t9gA:
11.03
3kp6B-5t9gA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 11 PHE A 460
TRP A 657
GLY A 550
ASN A 508
ILE A 569
 None
GIF  A 901 ( 4.4A)
None
None
None
 1.28A 3owxA-5t9gA:
undetectable
3owxB-5t9gA:
undetectable		 3owxA-5t9gA:
13.92
3owxB-5t9gA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 LEU A 554
SER A 530
TYR A 536
TRP A 461
PRO A 512
 None
GIF  A 901 ( 4.7A)
None
None
None
 1.48A 3r94A-5t9gA:
9.5		 3r94A-5t9gA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 HIS A 798
SER A 325
ASN A 795
 None
 0.89A 3s8pB-5t9gA:
undetectable		 3s8pB-5t9gA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 SER A 731
VAL A 676
ILE A 626
THR A 735
 None
 0.95A 3tneB-5t9gA:
undetectable		 3tneB-5t9gA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASP A 579
VAL A 578
GLY A 577
TYR A 580
 None
 1.30A 3w9tA-5t9gA:
undetectable		 3w9tA-5t9gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASP A 579
VAL A 578
GLY A 577
TYR A 580
 None
 1.29A 3w9tB-5t9gA:
undetectable		 3w9tB-5t9gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASP A 579
VAL A 578
GLY A 577
TYR A 580
 None
 1.29A 3w9tC-5t9gA:
undetectable		 3w9tC-5t9gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASP A 579
VAL A 578
GLY A 577
TYR A 580
 None
 1.30A 3w9tD-5t9gA:
undetectable		 3w9tD-5t9gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASP A 579
VAL A 578
GLY A 577
TYR A 580
 None
 1.30A 3w9tE-5t9gA:
undetectable		 3w9tE-5t9gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASP A 579
VAL A 578
GLY A 577
TYR A 580
 None
 1.30A 3w9tF-5t9gA:
undetectable		 3w9tF-5t9gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ASP A 579
VAL A 578
GLY A 577
TYR A 580
 None
 1.29A 3w9tG-5t9gA:
undetectable		 3w9tG-5t9gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 TYR A 520
LEU A 524
TRP A 381
ASN A 508
 None
 1.19A 4f8yC-5t9gA:
undetectable
4f8yD-5t9gA:
undetectable		 4f8yC-5t9gA:
12.45
4f8yD-5t9gA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 ILE A 121
ARG A 124
LEU A 126
ILE A 108
THR A 182
 None
 1.01A 4kjlA-5t9gA:
undetectable		 4kjlA-5t9gA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 GLY A 170
ASP A 323
ILE A 157
GLY A  89
PHE A  40
 None
 1.25A 4obwC-5t9gA:
undetectable		 4obwC-5t9gA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 LEU A 524
MET A 549
TYR A 543
 None
 0.75A 4p6xG-5t9gA:
undetectable		 4p6xG-5t9gA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_C_CLQC1079_0
(SAPOSIN-B)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 ARG A 338
MET A 326
GLU A 794
LEU A 817
 EDO  A 903 (-4.2A)
None
None
None
 1.44A 4v2oA-5t9gA:
undetectable
4v2oC-5t9gA:
undetectable		 4v2oA-5t9gA:
8.08
4v2oC-5t9gA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 11 ALA A 330
GLY A 792
VAL A  69
SER A 325
GLY A 328
 None
 1.26A 4xnxA-5t9gA:
undetectable		 4xnxA-5t9gA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 11 TYR A 131
TYR A 403
ILE A 437
LEU A 415
LEU A 492
 None
 1.22A 4yvpA-5t9gA:
9.1		 4yvpA-5t9gA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 11 PHE A 460
TRP A 657
GLY A 550
ASN A 508
ILE A 569
 None
GIF  A 901 ( 4.4A)
None
None
None
 1.33A 4zvmA-5t9gA:
undetectable
4zvmB-5t9gA:
undetectable		 4zvmA-5t9gA:
13.92
4zvmB-5t9gA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 GLY A 317
ILE A 564
GLY A 571
PHE A 573
 None
 0.86A 5alcL-5t9gA:
6.0		 5alcL-5t9gA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 HIS A 798
SER A 325
ASN A 795
 None
 0.80A 5cprB-5t9gA:
undetectable		 5cprB-5t9gA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 ARG A 225
LYS A 276
GLU A 278
 None
 0.78A 5d0yA-5t9gA:
undetectable		 5d0yA-5t9gA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 GLY A  86
HIS A 159
ALA A  77
THR A  81
 None
 0.96A 5eevL-5t9gA:
undetectable
5eevV-5t9gA:
1.9		 5eevL-5t9gA:
6.74
5eevV-5t9gA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 GLY A  86
HIS A 159
ALA A  77
THR A  81
 None
 0.96A 5eewL-5t9gA:
undetectable
5eewV-5t9gA:
undetectable		 5eewL-5t9gA:
6.74
5eewV-5t9gA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 GLY A  86
HIS A 159
ALA A  77
THR A  81
 None
 0.96A 5ef3L-5t9gA:
undetectable
5ef3V-5t9gA:
undetectable		 5ef3L-5t9gA:
6.74
5ef3V-5t9gA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 TYR A 119
TYR A 403
SER A 134
 None
 0.99A 5iktB-5t9gA:
undetectable		 5iktB-5t9gA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 ARG A 589
GLY A 585
HIS A 798
ASN A 800
LEU A 799
 None
 1.33A 5lsuB-5t9gA:
undetectable		 5lsuB-5t9gA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 ASP A 414
PHE A 136
GLY A 112
GLY A 132
 None
 1.00A 5n9xA-5t9gA:
undetectable		 5n9xA-5t9gA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 LEU A 818
LEU A 817
ALA A 816
ILE A 784
LEU A 843
 None
 1.03A 5toaA-5t9gA:
undetectable		 5toaA-5t9gA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 SER A 513
THR A 448
PHE A 451
PRO A 465
 None
 1.17A 5vkqA-5t9gA:
undetectable
5vkqB-5t9gA:
undetectable		 5vkqA-5t9gA:
18.53
5vkqB-5t9gA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 SER A 513
THR A 448
PHE A 451
PRO A 465
 None
 1.16A 5vkqB-5t9gA:
undetectable
5vkqC-5t9gA:
undetectable		 5vkqB-5t9gA:
18.53
5vkqC-5t9gA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 SER A 513
THR A 448
PHE A 451
PRO A 465
 None
 1.17A 5vkqC-5t9gA:
undetectable
5vkqD-5t9gA:
undetectable		 5vkqC-5t9gA:
18.53
5vkqD-5t9gA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 LEU A 744
PHE A 782
THR A 811
SER A 835
ILE A 780
 None
 1.02A 6debB-5t9gA:
undetectable		 6debB-5t9gA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 5t9g GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 11 GLY A 597
GLY A 599
ASP A 579
LEU A 603
TRP A 659
 None
 1.26A 6i5zD-5t9gA:
undetectable		 6i5zD-5t9gA:
18.95