SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_B_C2FB1420_0
(GLYCINE
N-METHYLTRANSFERASE)		 5t9p RIBOSOME BIOGENESIS
PROTEIN 15
(Saccharomyces
cerevisiae) 		5 / 10 LEU B 157
MET B 158
SER B 108
LEU B 162
MET B 152
 None
 1.43A 2idkA-5t9pB:
undetectable
2idkB-5t9pB:
undetectable
2idkC-5t9pB:
undetectable
2idkD-5t9pB:
undetectable		 2idkA-5t9pB:
16.72
2idkB-5t9pB:
16.72
2idkC-5t9pB:
16.72
2idkD-5t9pB:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5t9p RIBOSOME BIOGENESIS
PROTEIN 15
(Saccharomyces
cerevisiae) 		5 / 12 SER B  96
VAL B  95
GLN B 113
PHE B 114
PHE B 111
 CL  B 206 ( 4.6A)
None
None
None
None
 1.33A 2vdyA-5t9pB:
undetectable		 2vdyA-5t9pB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5t9p RIBOSOME BIOGENESIS
PROTEIN 15
(Saccharomyces
cerevisiae) 		5 / 12 SER B  96
VAL B  95
GLN B 113
PHE B 114
PHE B 111
 CL  B 206 ( 4.6A)
None
None
None
None
 1.31A 2vdyB-5t9pB:
undetectable		 2vdyB-5t9pB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5t9p RIBOSOME BIOGENESIS
PROTEIN 15
(Saccharomyces
cerevisiae) 		5 / 12 SER B  96
VAL B  95
GLN B 113
PHE B 114
PHE B 111
 CL  B 206 ( 4.6A)
None
None
None
None
 1.38A 4c49B-5t9pB:
undetectable		 4c49B-5t9pB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5t9p RIBOSOME BIOGENESIS
PROTEIN 15
(Saccharomyces
cerevisiae) 		5 / 12 SER B  96
VAL B  95
GLN B 113
PHE B 114
PHE B 111
 CL  B 206 ( 4.6A)
None
None
None
None
 1.36A 4c49C-5t9pB:
undetectable		 4c49C-5t9pB:
19.09