SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 TRP A 237
GLU A 193
TYR A 195
 None
IMD  A 402 (-3.6A)
None
 1.23A 2a3aA-5t9xA:
undetectable		 2a3aA-5t9xA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 ASP A 331
ASP A  73
ASP A 116
 NA  A 401 (-3.2A)
None
None
 0.37A 2igtA-5t9xA:
undetectable		 2igtA-5t9xA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 9 ILE A 121
ILE A 300
PHE A  75
ILE A 169
VAL A  56
 None
 1.28A 2ygpA-5t9xA:
undetectable		 2ygpA-5t9xA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 GLU A 193
ALA A 194
TRP A 179
GLY A 196
SER A 172
 IMD  A 402 (-3.6A)
None
IMD  A 402 (-3.5A)
None
None
 1.44A 3ou6D-5t9xA:
undetectable		 3ou6D-5t9xA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 9 ILE A 298
ILE A 300
VAL A 163
ILE A 192
ILE A 191
 None
 1.24A 3p4wB-5t9xA:
undetectable		 3p4wB-5t9xA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 THR A 173
SER A 197
ARG A 199
 None
 0.80A 3phnA-5t9xA:
undetectable		 3phnA-5t9xA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 TYR A 195
SER A 306
ASP A 177
ILE A 121
 None
None
IMD  A 402 (-3.5A)
None
 1.29A 3uj7B-5t9xA:
undetectable		 3uj7B-5t9xA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 TRP A  99
TRP A 107
THR A 105
 None
 1.22A 4bboB-5t9xA:
undetectable		 4bboB-5t9xA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 ASP A 212
LEU A 313
ARG A 308
 None
 0.95A 5e8qA-5t9xA:
undetectable		 5e8qA-5t9xA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 6 ILE A 191
VAL A 157
TYR A 162
VAL A 163
 None
 1.00A 5jwaH-5t9xA:
undetectable		 5jwaH-5t9xA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 10 ILE A 192
ILE A 191
ILE A 298
ILE A 300
ILE A 299
 None
 1.10A 5murE-5t9xA:
undetectable		 5murE-5t9xA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5t9x GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 TYR A 229
ASP A 228
GLN A 230
 None
 0.88A 6g1pA-5t9xA:
undetectable		 6g1pA-5t9xA:
19.95