SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ta9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 ARG A 383
LEU A  76
PRO A 166
VAL A 103
 None
 1.01A 1hrkA-5ta9A:
undetectable		 1hrkA-5ta9A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 4 ASP A 320
HIS A 302
ARG A 273
GLU A 262
 None
GAL  A 501 (-3.9A)
GAL  A 501 (-2.8A)
GAL  A 501 (-2.7A)
 1.36A 1lqtA-5ta9A:
undetectable		 1lqtA-5ta9A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 ASP A 218
ASP A 237
LYS A 191
 None
 0.94A 1lqtB-5ta9A:
undetectable		 1lqtB-5ta9A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 ASP A 218
ASP A 237
LYS A 191
 None
 0.95A 1lquB-5ta9A:
undetectable		 1lquB-5ta9A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 VAL A 150
TRP A 206
TRP A 198
GLU A 207
 None
 1.15A 1om5A-5ta9A:
undetectable
1om5B-5ta9A:
undetectable		 1om5A-5ta9A:
21.00
1om5B-5ta9A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 TRP A 198
GLU A 207
VAL A 150
TRP A 206
 None
 1.17A 1rs6A-5ta9A:
undetectable
1rs6B-5ta9A:
undetectable		 1rs6A-5ta9A:
21.00
1rs6B-5ta9A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 VAL A 150
TRP A 206
TRP A 198
GLU A 207
 None
 1.18A 2g6hA-5ta9A:
undetectable
2g6hB-5ta9A:
undetectable		 2g6hA-5ta9A:
21.49
2g6hB-5ta9A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 TYR A 251
ASP A 332
TYR A 256
TYR A 294
 None
 1.38A 2ha2A-5ta9A:
undetectable		 2ha2A-5ta9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 TYR A 251
ASP A 332
TYR A 256
TYR A 294
 None
 1.38A 2ha2B-5ta9A:
undetectable		 2ha2B-5ta9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 ARG A 383
LEU A  76
PRO A 166
VAL A 103
 None
 0.97A 2hrcA-5ta9A:
undetectable		 2hrcA-5ta9A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2002_0
(TRYPTOPHAN
HALOGENASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		5 / 12 ILE A 275
HIS A 302
GLU A 262
TYR A 376
PHE A 125
 None
GAL  A 501 (-3.9A)
GAL  A 501 (-2.7A)
None
GAL  A 501 (-4.7A)
 1.46A 2oa1A-5ta9A:
undetectable		 2oa1A-5ta9A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 ASP A 332
TYR A 251
GLY A 312
PRO A 331
 None
 0.90A 2ys6A-5ta9A:
undetectable		 2ys6A-5ta9A:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 TRP A 198
GLU A 207
VAL A 150
TRP A 206
 None
 1.18A 3b3pA-5ta9A:
undetectable
3b3pB-5ta9A:
undetectable		 3b3pA-5ta9A:
21.40
3b3pB-5ta9A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 TYR A 186
PHE A 164
GLN A 180
ASP A 245
 None
None
AAL  A 502 (-3.2A)
AAL  A 502 (-2.7A)
 0.92A 3mjrD-5ta9A:
undetectable		 3mjrD-5ta9A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 HIS A 302
ASP A  90
HIS A 244
HIS A 371
 GAL  A 501 (-3.9A)
AAL  A 502 ( 3.7A)
AAL  A 502 (-3.3A)
None
 1.24A 3zodA-5ta9A:
undetectable		 3zodA-5ta9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 5 LEU A  76
ASP A  79
ARG A  88
ILE A  86
 None
 1.41A 4mwrA-5ta9A:
12.5		 4mwrA-5ta9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 TRP A 198
GLU A 207
VAL A 150
TRP A 206
 None
 1.21A 4uchA-5ta9A:
undetectable
4uchB-5ta9A:
undetectable		 4uchA-5ta9A:
20.88
4uchB-5ta9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 TRP A 198
GLU A 207
VAL A 150
TRP A 206
 None
 1.21A 4v3wA-5ta9A:
undetectable
4v3wB-5ta9A:
undetectable		 4v3wA-5ta9A:
21.40
4v3wB-5ta9A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 VAL A 150
TRP A 206
TRP A 198
GLU A 207
 None
 1.15A 6auuA-5ta9A:
undetectable
6auuB-5ta9A:
undetectable		 6auuA-5ta9A:
10.03
6auuB-5ta9A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		3 / 3 ARG A 152
LYS A 208
ARG A 129
 None
 1.37A 6az3C-5ta9A:
undetectable
6az3L-5ta9A:
undetectable
6az3M-5ta9A:
undetectable		 6az3C-5ta9A:
11.34
6az3L-5ta9A:
12.01
6az3M-5ta9A:
11.73