SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 6 LEU A 467
GLY A 470
LYS A 520
TYR A 466
 None
 1.27A 1gtiC-5tc3A:
undetectable		 1gtiC-5tc3A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 5 LEU A 467
GLY A 470
LYS A 520
TYR A 466
 None
 1.27A 1gtiF-5tc3A:
undetectable		 1gtiF-5tc3A:
16.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 11 ASP A 277
ASN A 306
ARG A 325
GLY A 331
GLY A 418
 None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
5GP  A 600 (-3.3A)
5GP  A 600 (-3.1A)
 1.08A 1jr1A-5tc3A:
59.0		 1jr1A-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		9 / 11 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
GLY A 329
THR A 336
GLY A 418
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
None
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
5GP  A 600 (-3.1A)
 0.70A 1jr1A-5tc3A:
59.0		 1jr1A-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		8 / 11 ASP A 277
SER A 279
ASN A 306
ARG A 325
MET A 328
GLY A 329
THR A 336
GLN A 448
 None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
None
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
None
 0.34A 1jr1A-5tc3A:
59.0		 1jr1A-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 11 SER A 279
ASN A 306
MET A 328
GLY A 329
THR A 336
GLY A 449
GLN A 448
 None
5GP  A 600 (-3.2A)
None
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
5GP  A 600 ( 3.8A)
None
 1.21A 1jr1A-5tc3A:
59.0		 1jr1A-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 11 SER A 279
SER A 278
GLY A 254
THR A 255
GLN A 286
 None
 1.32A 1jr1A-5tc3A:
59.0		 1jr1A-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 8 ASP A 277
ASN A 306
ARG A 325
GLY A 331
GLY A 418
 None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
5GP  A 600 (-3.3A)
5GP  A 600 (-3.1A)
 0.95A 1jr1B-5tc3A:
58.1		 1jr1B-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 8 ASP A 277
SER A 279
ASN A 306
ARG A 325
GLY A 329
THR A 336
GLN A 448
 None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
None
 0.35A 1jr1B-5tc3A:
58.1		 1jr1B-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 8 ASP A 277
SER A 279
ASN A 306
ARG A 325
GLY A 329
THR A 336
GLY A 418
 None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
5GP  A 600 (-3.1A)
 0.57A 1jr1B-5tc3A:
58.1		 1jr1B-5tc3A:
62.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
GLY A 329
GLY A 418
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 ( 3.2A)
5GP  A 600 (-3.1A)
 0.59A 1me7A-5tc3A:
46.8		 1me7A-5tc3A:
34.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 10 ASP A 277
SER A 278
SER A 279
ASN A 306
GLY A 329
GLY A 418
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 ( 3.2A)
5GP  A 600 (-3.1A)
 0.56A 1mehA-5tc3A:
45.0		 1mehA-5tc3A:
34.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
GLY A 418
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
 0.58A 1meiA-5tc3A:
46.0		 1meiA-5tc3A:
34.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 ILE A 202
GLN A 201
THR A 206
LEU A 196
LEU A 224
 None
None
None
GDP  A 603 ( 4.6A)
GDP  A 603 ( 4.3A)
 1.02A 1rjdA-5tc3A:
undetectable		 1rjdA-5tc3A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 ILE A 202
GLN A 201
THR A 206
LEU A 196
LEU A 224
 None
None
None
GDP  A 603 ( 4.6A)
GDP  A 603 ( 4.3A)
 1.04A 1rjdB-5tc3A:
undetectable		 1rjdB-5tc3A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 ILE A 202
GLN A 201
THR A 206
LEU A 196
LEU A 224
 None
None
None
GDP  A 603 ( 4.6A)
GDP  A 603 ( 4.3A)
 1.03A 1rjdC-5tc3A:
undetectable		 1rjdC-5tc3A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 5 GLY A 479
ILE A 478
VAL A  55
SER A 474
 None
 1.21A 1rs7A-5tc3A:
undetectable		 1rs7A-5tc3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 6 GLY A 479
ILE A 478
VAL A  55
SER A 474
 None
 1.07A 1rs7B-5tc3A:
undetectable		 1rs7B-5tc3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 LEU A 224
ILE A 213
VAL A 221
ASN A 122
LEU A 196
 GDP  A 603 ( 4.3A)
None
None
None
GDP  A 603 ( 4.6A)
 1.22A 1wsvA-5tc3A:
undetectable		 1wsvA-5tc3A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 LEU A 224
ILE A 213
VAL A 221
ASN A 122
LEU A 196
 GDP  A 603 ( 4.3A)
None
None
None
GDP  A 603 ( 4.6A)
 1.23A 1wsvB-5tc3A:
undetectable		 1wsvB-5tc3A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 6 LEU A  61
ILE A  96
ILE A 365
ARG A 325
 None
None
None
5GP  A 600 (-3.1A)
 0.98A 2q8hA-5tc3A:
undetectable		 2q8hA-5tc3A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 127
THR A 184
MET A 183
ASP A 168
MET A 223
 None
ATP  A 601 (-2.8A)
None
ATP  A 601 (-2.3A)
GDP  A 602 (-4.7A)
 0.87A 2qo4A-5tc3A:
undetectable		 2qo4A-5tc3A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ILE A  94
GLY A 250
LEU A 271
LEU A 300
 None
 0.79A 2vctA-5tc3A:
undetectable		 2vctA-5tc3A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 ILE A 163
THR A 184
VAL A 187
ILE A 188
PRO A 212
 ATP  A 601 ( 4.6A)
ATP  A 601 (-2.8A)
ATP  A 601 (-4.0A)
ATP  A 601 (-4.2A)
ATP  A 601 ( 4.9A)
 0.52A 2yzqA-5tc3A:
9.6		 2yzqA-5tc3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 5 ASP A 367
ILE A 376
ILE A 365
GLY A 368
 5GP  A 600 (-2.4A)
None
None
5GP  A 600 ( 3.4A)
 0.95A 3bufA-5tc3A:
undetectable		 3bufA-5tc3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 7 VAL A 370
GLN A 346
VAL A 350
ALA A 384
 None
 0.98A 3kp6B-5tc3A:
undetectable		 3kp6B-5tc3A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 12 ILE A 163
THR A 165
ASP A 168
THR A 184
VAL A 187
ILE A 188
PRO A 212
 ATP  A 601 ( 4.6A)
ATP  A 601 (-2.7A)
ATP  A 601 (-2.3A)
ATP  A 601 (-2.8A)
ATP  A 601 (-4.0A)
ATP  A 601 (-4.2A)
ATP  A 601 ( 4.9A)
 0.54A 3kpbA-5tc3A:
14.5		 3kpbA-5tc3A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 12 ILE A 163
THR A 165
ASP A 168
THR A 184
VAL A 187
ILE A 188
PRO A 212
 ATP  A 601 ( 4.6A)
ATP  A 601 (-2.7A)
ATP  A 601 (-2.3A)
ATP  A 601 (-2.8A)
ATP  A 601 (-4.0A)
ATP  A 601 (-4.2A)
ATP  A 601 ( 4.9A)
 0.54A 3kpbC-5tc3A:
14.9		 3kpbC-5tc3A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 10 ILE A 163
THR A 165
ASP A 168
THR A 184
VAL A 187
ILE A 188
 ATP  A 601 ( 4.6A)
ATP  A 601 (-2.7A)
ATP  A 601 (-2.3A)
ATP  A 601 (-2.8A)
ATP  A 601 (-4.0A)
ATP  A 601 (-4.2A)
 0.52A 3kpbD-5tc3A:
14.8		 3kpbD-5tc3A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 11 ILE A 163
THR A 165
ASP A 168
THR A 184
VAL A 187
ILE A 188
PRO A 212
 ATP  A 601 ( 4.6A)
ATP  A 601 (-2.7A)
ATP  A 601 (-2.3A)
ATP  A 601 (-2.8A)
ATP  A 601 (-4.0A)
ATP  A 601 (-4.2A)
ATP  A 601 ( 4.9A)
 0.45A 3kpcA-5tc3A:
14.5		 3kpcA-5tc3A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 12 ILE A 163
THR A 165
ASP A 168
THR A 184
VAL A 187
ILE A 188
PRO A 212
 ATP  A 601 ( 4.6A)
ATP  A 601 (-2.7A)
ATP  A 601 (-2.3A)
ATP  A 601 (-2.8A)
ATP  A 601 (-4.0A)
ATP  A 601 (-4.2A)
ATP  A 601 ( 4.9A)
 0.43A 3kpdB-5tc3A:
14.0		 3kpdB-5tc3A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 12 ILE A 163
THR A 165
ASP A 168
THR A 184
VAL A 187
ILE A 188
PRO A 212
 ATP  A 601 ( 4.6A)
ATP  A 601 (-2.7A)
ATP  A 601 (-2.3A)
ATP  A 601 (-2.8A)
ATP  A 601 (-4.0A)
ATP  A 601 (-4.2A)
ATP  A 601 ( 4.9A)
 0.52A 3kpdC-5tc3A:
14.5		 3kpdC-5tc3A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 8 ILE A 478
VAL A  43
THR A 377
ILE A 380
 None
 0.79A 3p4wC-5tc3A:
undetectable		 3p4wC-5tc3A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 7 GLY A 281
ASP A 277
VAL A 275
ILE A 326
 None
 0.59A 3t3cA-5tc3A:
undetectable		 3t3cA-5tc3A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 PHE A  71
PRO A  70
LEU A 483
VAL A  55
GLN A 472
 None
 1.29A 4a84A-5tc3A:
undetectable		 4a84A-5tc3A:
14.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
GLN A 448
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
None
None
 0.31A 4af0A-5tc3A:
56.5		 4af0A-5tc3A:
64.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
GLY A 418
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
None
5GP  A 600 (-3.1A)
 0.44A 4af0A-5tc3A:
56.5		 4af0A-5tc3A:
64.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 8 SER A 279
ASN A 306
MET A 328
GLY A 449
GLN A 448
 None
5GP  A 600 (-3.2A)
None
5GP  A 600 ( 3.8A)
None
 1.15A 4af0A-5tc3A:
56.5		 4af0A-5tc3A:
64.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_B_MOAB1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 10 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
GLN A 448
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
None
None
 0.29A 4af0B-5tc3A:
56.6		 4af0B-5tc3A:
64.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_B_MOAB1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		7 / 10 ASP A 277
SER A 278
SER A 279
ASN A 306
ARG A 325
MET A 328
GLY A 418
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
None
5GP  A 600 (-3.1A)
 0.44A 4af0B-5tc3A:
56.6		 4af0B-5tc3A:
64.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AF0_B_MOAB1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 10 SER A 279
ASN A 306
MET A 328
GLY A 449
GLN A 448
 None
5GP  A 600 (-3.2A)
None
5GP  A 600 ( 3.8A)
None
 1.14A 4af0B-5tc3A:
56.6		 4af0B-5tc3A:
64.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 8 ASP A 277
SER A 278
SER A 279
ASN A 306
THR A 336
 None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-2.6A)
 0.88A 4fo4A-5tc3A:
47.9		 4fo4A-5tc3A:
32.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 8 SER A 278
SER A 279
ASN A 306
THR A 336
GLY A 418
 None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-2.6A)
5GP  A 600 (-3.1A)
 0.73A 4fo4A-5tc3A:
47.9		 4fo4A-5tc3A:
32.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 8 SER A 278
SER A 279
ASN A 306
GLY A 329
THR A 336
GLY A 418
 None
None
5GP  A 600 (-3.2A)
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
5GP  A 600 (-3.1A)
 0.63A 4fo4B-5tc3A:
47.8		 4fo4B-5tc3A:
32.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FXS_A_MOAA702_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 9 ASP A 277
SER A 278
SER A 279
GLY A 329
THR A 336
 None
None
None
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
 0.69A 4fxsA-5tc3A:
50.5		 4fxsA-5tc3A:
39.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FXS_A_MOAA702_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		6 / 9 SER A 278
SER A 279
ASN A 306
GLY A 329
THR A 336
ASP A 367
 None
None
5GP  A 600 (-3.2A)
5GP  A 600 ( 3.2A)
5GP  A 600 (-2.6A)
5GP  A 600 (-2.4A)
 0.55A 4fxsA-5tc3A:
50.5		 4fxsA-5tc3A:
39.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 11 LEU A 248
VAL A  72
ILE A 365
GLY A 323
ILE A  94
 None
 0.99A 4njtA-5tc3A:
undetectable		 4njtA-5tc3A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 11 LEU A 248
VAL A  72
ILE A 365
GLY A 323
ILE A  94
 None
 0.96A 4njtC-5tc3A:
undetectable		 4njtC-5tc3A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 11 LEU A 248
VAL A  72
ILE A 365
GLY A 323
ILE A  94
 None
 0.91A 4rvjA-5tc3A:
undetectable		 4rvjA-5tc3A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 11 LEU A 248
VAL A  72
ILE A 365
GLY A 323
ILE A  94
 None
 0.92A 4rvjC-5tc3A:
undetectable		 4rvjC-5tc3A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		3 / 3 ASN A 469
SER A  52
SER A  53
 None
 0.79A 5gsnA-5tc3A:
undetectable		 5gsnA-5tc3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 ARG A 111
LEU A 263
ALA A 252
GLY A 270
ALA A 269
 None
 0.90A 5jw1B-5tc3A:
undetectable		 5jw1B-5tc3A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		4 / 7 LEU A 203
ILE A 164
THR A 165
MET A 223
 None
None
ATP  A 601 (-2.7A)
GDP  A 602 (-4.7A)
 1.43A 5ljcA-5tc3A:
undetectable		 5ljcA-5tc3A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 ASN A 100
GLN A 448
SER A 453
GLY A 452
THR A 451
 None
 1.21A 5oj0A-5tc3A:
undetectable		 5oj0A-5tc3A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		3 / 3 GLY A 368
VAL A  79
MET A  76
 5GP  A 600 ( 3.4A)
None
5GP  A 600 ( 2.9A)
 0.55A 5ycpA-5tc3A:
undetectable		 5ycpA-5tc3A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 LEU A 276
VAL A 353
ARG A 325
ILE A 326
ASP A 367
 None
None
5GP  A 600 (-3.1A)
None
5GP  A 600 (-2.4A)
 1.39A 6bxnA-5tc3A:
undetectable		 6bxnA-5tc3A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 9 LEU A 471
SER A 474
ILE A 380
VAL A 387
ILE A 376
 None
 1.22A 6ef6A-5tc3A:
undetectable		 6ef6A-5tc3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.11A 6ew0B-5tc3A:
undetectable		 6ew0B-5tc3A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.11A 6ew0D-5tc3A:
undetectable		 6ew0D-5tc3A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.11A 6ew0H-5tc3A:
undetectable		 6ew0H-5tc3A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE
(Eremothecium
gossypii) 		5 / 12 VAL A 110
LEU A  61
LEU A  67
ALA A 251
LEU A 300
 None
 1.11A 6ew0I-5tc3A:
undetectable		 6ew0I-5tc3A:
9.76