SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tcp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5tcp LIPOPROTEIN PRGK
(Salmonella
enterica) 		4 / 8 GLY 0  26
ILE 0  58
LEU 0  24
ASP 0  50
 None
 0.92A 1jg4A-5tcp0:
undetectable		 1jg4A-5tcp0:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 5tcp PROTEIN PRGH
(Salmonella
enterica) 		4 / 7 ALA 1 286
TYR 1 285
TYR 1 245
PHE 1 250
 None
 1.18A 2ajvH-5tcp1:
undetectable
2ajvL-5tcp1:
undetectable		 2ajvH-5tcp1:
21.38
2ajvL-5tcp1:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5tcp PROTEIN PRGH
(Salmonella
enterica) 		4 / 5 LEU 1 307
GLY 1 306
PHE 1 342
PHE 1 357
 None
 1.14A 3smtA-5tcp1:
undetectable		 3smtA-5tcp1:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 5tcp PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 MET 1 267
GLU 1 271
LEU 1 275
 None
 0.54A 4v2oB-5tcp1:
undetectable		 4v2oB-5tcp1:
15.52