SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tcv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5tcv 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 1
(Petunia
x
hybrida) 		6 / 12 HIS A 177
ASP A 179
LEU A 195
HIS A 234
SER A 246
PHE A 250
 NI  A 401 ( 3.3A)
NI  A 401 ( 2.4A)
1AC  A 402 ( 4.5A)
NI  A 401 ( 3.3A)
None
None
 0.85A 1uobA-5tcvA:
19.6		 1uobA-5tcvA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 5tcv 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 1
(Petunia
x
hybrida) 		4 / 8 PHE A 117
THR A  53
ASN A 161
SER A 160
 None
 1.05A 2a8tB-5tcvA:
undetectable		 2a8tB-5tcvA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 5tcv 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 1
(Petunia
x
hybrida) 		3 / 3 PHE A   4
SER A 212
LEU A 186
 None
None
1AC  A 402 ( 3.8A)
 0.78A 2w1bA-5tcvA:
undetectable		 2w1bA-5tcvA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5tcv 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 1
(Petunia
x
hybrida) 		3 / 3 ASP A 241
GLY A 242
ASP A 190
 None
 0.68A 4xdtA-5tcvA:
undetectable		 4xdtA-5tcvA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 5tcv 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 1
(Petunia
x
hybrida) 		3 / 3 LYS A 191
ARG A 210
HIS A 211
 None
 1.09A 4zbrA-5tcvA:
undetectable		 4zbrA-5tcvA:
20.14