SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5td2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_D_DVAD8_0 (GRAMICIDIN A)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	3 / 3	TRP A 766 VAL A 783 TRP A 784	None	1.15A	1gmkC-5td2A: undetectable 1gmkD-5td2A: undetectable	1gmkC-5td2A: 3.97 1gmkD-5td2A: 3.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IEP_A_STIA201_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 12	LEU A 593 VAL A 601 ALA A 617 MET A 641 PHE A 673 GLY A 677 ALA A 740	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A)	0.85A	1iepA-5td2A: 29.0	1iepA-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IEP_B_STIB202_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	LEU A 593 ALA A 617 MET A 641 PHE A 673 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	1.05A	1iepB-5td2A: 28.9	1iepB-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IEP_B_STIB202_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 12	LEU A 593 VAL A 601 ALA A 617 MET A 641 PHE A 673 GLY A 677 ALA A 740	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A)	0.87A	1iepB-5td2A: 28.9	1iepB-5td2A: 41.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_G_FUAG708_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 11	PHE A 719 SER A 779 PHE A 847 VAL A 649 PHE A 644	None	1.38A	1q23G-5td2A: undetectable	1q23G-5td2A: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_K_FUAK712_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 10	PHE A 719 SER A 779 PHE A 847 VAL A 649 PHE A 644	None	1.36A	1q23K-5td2A: undetectable	1q23K-5td2A: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 7	TYR A 676 MET A 735 ASP A 734 ASP A 733	None	1.47A	1t03A-5td2A: undetectable	1t03A-5td2A: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CEO_B_T44B1395_1 (THYROXINE-BINDING GLOBULIN)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 10	ALA A 794 GLN A 853 LEU A 850 LEU A 854 LEU A 829	None	1.39A	2ceoB-5td2A: undetectable	2ceoB-5td2A: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 7	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.91A	2dyrN-5td2A: 2.4 2dyrW-5td2A: undetectable	2dyrN-5td2A: 20.72 2dyrW-5td2A: 15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIN_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 6	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.90A	2einN-5td2A: 2.7 2einW-5td2A: undetectable	2einN-5td2A: 20.72 2einW-5td2A: 15.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2HYY_A_STIA600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	VAL A 601 ALA A 617 MET A 641 PHE A 673 GLY A 677 ALA A 740	7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A)	0.78A	2hyyA-5td2A: 28.9	2hyyA-5td2A: 43.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2HYY_B_STIB600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	VAL A 601 ALA A 617 MET A 641 PHE A 673 GLY A 677 ALA A 740	7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A)	0.75A	2hyyB-5td2A: 29.2	2hyyB-5td2A: 43.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ITY_A_IREA2020_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 12	LEU A 593 GLY A 594 VAL A 601 ALA A 617 LYS A 619 MET A 641 GLY A 677 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.2A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.1A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.83A	2ityA-5td2A: 24.2	2ityA-5td2A: 34.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTH FACTOR RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	9 / 12	GLY A 594 VAL A 601 ALA A 617 LEU A 671 MET A 674 GLY A 677 MET A 730 ALA A 740 ASP A 741	7AE A1000 ( 4.2A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A) 7AE A1000 (-3.6A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.49A	2wgjA-5td2A: 30.9	2wgjA-5td2A: 43.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XP2_A_VGHA9000_1 (TYROSINE-PROTEIN KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 9	LEU A 593 VAL A 601 ALA A 617 LEU A 671 MET A 674 GLY A 677 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.41A	2xp2A-5td2A: 29.4	2xp2A-5td2A: 37.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 7	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.93A	3ablA-5td2A: 2.8 3ablJ-5td2A: undetectable	3ablA-5td2A: 20.72 3ablJ-5td2A: 15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 6	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.98A	3ag1N-5td2A: 3.2 3ag1W-5td2A: undetectable	3ag1N-5td2A: 20.72 3ag1W-5td2A: 15.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 10	LEU A 593 ALA A 617 LYS A 619 LEU A 671 MET A 674 GLY A 677	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.1A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A)	0.47A	3aoxA-5td2A: 11.8	3aoxA-5td2A: 35.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_A_NILA600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	ALA A 617 MET A 641 GLY A 677 PHE A 719 HIS A 721 ALA A 740	7AE A1000 (-3.3A) None 7AE A1000 ( 3.7A) None None 7AE A1000 ( 3.7A)	0.75A	3cs9A-5td2A: 29.5	3cs9A-5td2A: 42.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_B_NILB600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 12	ALA A 617 MET A 641 GLY A 677 HIS A 721 ALA A 740	7AE A1000 (-3.3A) None 7AE A1000 ( 3.7A) None 7AE A1000 ( 3.7A)	0.60A	3cs9B-5td2A: 30.3	3cs9B-5td2A: 42.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_C_NILC600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	ALA A 617 MET A 641 PHE A 673 PHE A 719 HIS A 721 ALA A 740	7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) None None 7AE A1000 ( 3.7A)	0.80A	3cs9C-5td2A: 29.5	3cs9C-5td2A: 42.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_D_NILD600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	ALA A 617 MET A 641 GLY A 677 PHE A 719 HIS A 721 ALA A 740	7AE A1000 (-3.3A) None 7AE A1000 ( 3.7A) None None 7AE A1000 ( 3.7A)	0.66A	3cs9D-5td2A: 22.2	3cs9D-5td2A: 42.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_D_NILD600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	ALA A 617 MET A 641 PHE A 673 GLY A 677 HIS A 721 ALA A 740	7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) None 7AE A1000 ( 3.7A)	0.61A	3cs9D-5td2A: 22.2	3cs9D-5td2A: 42.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MIY_B_B49B2_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 9	ALA A 617 LYS A 619 PHE A 673 MET A 674 GLY A 677	7AE A1000 (-3.3A) 7AE A1000 (-3.1A) 7AE A1000 (-4.1A) None 7AE A1000 ( 3.7A)	0.55A	3miyB-5td2A: 31.2	3miyB-5td2A: 38.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MS9_A_STIA1_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 12	LEU A 593 VAL A 601 ALA A 617 MET A 641 PHE A 673 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.98A	3ms9A-5td2A: 29.1	3ms9A-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_A_STIA1_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	LEU A 593 ALA A 617 MET A 641 PHE A 673 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.99A	3mssA-5td2A: 29.3	3mssA-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_A_STIA1_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	LEU A 593 VAL A 601 ALA A 617 MET A 641 PHE A 673 ALA A 740	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A)	0.75A	3mssA-5td2A: 29.3	3mssA-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_C_STIC1_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	LEU A 593 ALA A 617 MET A 641 PHE A 673 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	1.00A	3mssC-5td2A: 29.4	3mssC-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_C_STIC1_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	LEU A 593 VAL A 601 ALA A 617 MET A 641 PHE A 673 ALA A 740	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A)	0.75A	3mssC-5td2A: 29.4	3mssC-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_D_STID1_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	LEU A 593 ALA A 617 MET A 641 PHE A 673 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	1.00A	3mssD-5td2A: 29.3	3mssD-5td2A: 41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MSS_D_STID1_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 12	LEU A 593 ALA A 617 MET A 641 PHE A 673 GLY A 677 ALA A 740	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) None 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A)	0.84A	3mssD-5td2A: 29.3	3mssD-5td2A: 41.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V5W_A_8PRA701_2 (G-PROTEIN COUPLED RECEPTOR KINASE 2)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	3 / 3	LEU A 671 MET A 674 ASP A 678	7AE A1000 (-3.7A) None 7AE A1000 ( 4.8A)	0.63A	3v5wA-5td2A: 10.0	3v5wA-5td2A: 17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 6	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.98A	3wg7N-5td2A: undetectable 3wg7W-5td2A: undetectable	3wg7N-5td2A: 20.72 3wg7W-5td2A: 15.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WZE_A_BAXA1201_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 12	LEU A 593 VAL A 601 ALA A 617 LYS A 619 PHE A 673 GLY A 677 LEU A 714 HIS A 721	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.1A) 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) None None	0.67A	3wzeA-5td2A: 29.4	3wzeA-5td2A: 39.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZBF_A_VGHA3000_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 12	LEU A 593 ALA A 617 LEU A 671 MET A 674 GLY A 677 ASP A 678 THR A 681 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A) 7AE A1000 ( 4.8A) None 7AE A1000 (-4.4A)	0.61A	3zbfA-5td2A: 30.4	3zbfA-5td2A: 40.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 9	LEU A 593 VAL A 601 ALA A 617 LEU A 671 MET A 674 GLY A 677 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.52A	4anqA-5td2A: 29.0	4anqA-5td2A: 34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4ANS_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 9	LEU A 593 VAL A 601 ALA A 617 MET A 674 GLY A 677 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.57A	4ansA-5td2A: 28.9	4ansA-5td2A: 34.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4ASD_A_BAXA1500_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 12	LEU A 593 VAL A 601 ALA A 617 LYS A 619 PHE A 673 GLY A 677 LEU A 714 HIS A 721	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.1A) 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) None None	0.72A	4asdA-5td2A: 29.0	4asdA-5td2A: 36.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAA_A_RTZA401_1 (SERINE/THREONINE-PRO TEIN KINASE PIM-1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 11	VAL A 601 ALA A 617 LYS A 619 LEU A 671 ASP A 678 ASP A 741	7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.1A) 7AE A1000 (-3.7A) 7AE A1000 ( 4.8A) 7AE A1000 (-4.4A)	0.75A	4iaaA-5td2A: 20.8	4iaaA-5td2A: 25.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 12	VAL A 601 ALA A 617 PHE A 673 MET A 674 GLY A 677 ASN A 728 ALA A 740 ASP A 741	7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-4.1A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.7A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.60A	4twpA-5td2A: 29.9	4twpA-5td2A: 44.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	9 / 12	LEU A 593 VAL A 601 ALA A 617 PHE A 673 MET A 674 GLY A 677 ASN A 728 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-4.1A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.7A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.63A	4twpB-5td2A: 16.9	4twpB-5td2A: 44.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U5J_A_RXTA601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 11	LEU A 593 VAL A 601 ALA A 617 MET A 674 GLY A 677 ASN A 728 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.7A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.54A	4u5jA-5td2A: 21.7	4u5jA-5td2A: 38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U5J_B_RXTB601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 9	LEU A 593 VAL A 601 ALA A 617 MET A 674 GLY A 677 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.71A	4u5jB-5td2A: 21.5	4u5jB-5td2A: 38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_A_0LIA1776_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 12	ALA A 617 MET A 641 LEU A 714 HIS A 721 ALA A 740	7AE A1000 (-3.3A) None None None 7AE A1000 ( 3.7A)	0.71A	4v01A-5td2A: 29.6	4v01A-5td2A: 41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_B_0LIB1770_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 12	ALA A 617 MET A 641 LEU A 714 HIS A 721 ALA A 740	7AE A1000 (-3.3A) None None None 7AE A1000 ( 3.7A)	0.59A	4v01B-5td2A: 29.9	4v01B-5td2A: 41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 11	LEU A 593 ALA A 617 MET A 674 GLY A 677 ASN A 728 ALA A 740	7AE A1000 ( 3.9A) 7AE A1000 (-3.3A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.7A) 7AE A1000 ( 3.7A)	0.71A	4wa9A-5td2A: 27.8	4wa9A-5td2A: 42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 12	VAL A 601 ALA A 617 PHE A 673 MET A 674 GLY A 677 ASN A 728 ALA A 740	7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-4.1A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.7A) 7AE A1000 ( 3.7A)	0.61A	4wa9B-5td2A: 29.0	4wa9B-5td2A: 42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAA_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 9	LEU A 593 VAL A 601 ALA A 617 LEU A 671 MET A 674 GLY A 677 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.50A	5aaaA-5td2A: 12.8	5aaaA-5td2A: 38.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAB_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 10	LEU A 593 VAL A 601 ALA A 617 LEU A 671 MET A 674 GLY A 677 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.51A	5aabA-5td2A: 21.1	5aabA-5td2A: 38.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAC_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 10	LEU A 593 VAL A 601 ALA A 617 LEU A 671 MET A 674 GLY A 677 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 (-3.7A) None 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	0.38A	5aacA-5td2A: 21.2	5aacA-5td2A: 37.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AJQ_A_DB8A800_1 (SERINE/THREONINE-PRO TEIN KINASE 10)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 12	LEU A 593 GLY A 594 ALA A 617 PHE A 673 GLY A 677 ALA A 740 ASP A 741	7AE A1000 ( 3.9A) 7AE A1000 ( 4.2A) 7AE A1000 (-3.3A) 7AE A1000 (-4.1A) 7AE A1000 ( 3.7A) 7AE A1000 ( 3.7A) 7AE A1000 (-4.4A)	1.04A	5ajqA-5td2A: 17.8	5ajqA-5td2A: 25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_F_RAUF400_1 (IMINE REDUCTASE)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 10	GLY A 816 VAL A 788 LEU A 813 MET A 809 TYR A 812	None	1.46A	5g6sD-5td2A: 1.5 5g6sF-5td2A: 1.5	5g6sD-5td2A: 23.24 5g6sF-5td2A: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 7	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.93A	5iy5N-5td2A: undetectable 5iy5W-5td2A: undetectable	5iy5N-5td2A: 20.72 5iy5W-5td2A: 15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 12	LEU A 593 GLY A 594 VAL A 601 ALA A 617 ALA A 740	7AE A1000 ( 3.9A) 7AE A1000 ( 4.2A) 7AE A1000 ( 4.9A) 7AE A1000 (-3.3A) 7AE A1000 ( 3.7A)	0.28A	5xv7A-5td2A: 19.7	5xv7A-5td2A: 14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 6	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.95A	5z86N-5td2A: undetectable 5z86W-5td2A: undetectable	5z86N-5td2A: 20.72 5z86W-5td2A: 15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 6	ILE A 695 MET A 735 THR A 736 LEU A 731	None	0.97A	5zcoN-5td2A: 2.8 5zcoW-5td2A: undetectable	5zcoN-5td2A: 20.72 5zcoW-5td2A: 15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_B_STIB602_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 6	LEU A 593 PHE A 673 MET A 674 GLY A 677	7AE A1000 ( 3.9A) 7AE A1000 (-4.1A) None 7AE A1000 ( 3.7A)	0.60A	6hd4B-5td2A: 28.4	6hd4B-5td2A: 12.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GMK_D_DVAD8_0","GRAMICIDIN A","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",3,"TRP A 766;VAL A 783;TRP A 784","None","1.15A","1gmkC-5td2A:undetectable;1gmkD-5td2A:undetectable","1gmkC-5td2A:3.97;1gmkD-5td2A:3.97"],["1IEP_A_STIA201_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;MET A 641;PHE A 673;GLY A 677;ALA A 740","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 ( 3.7A)","0.85A","1iepA-5td2A:29.0","1iepA-5td2A:41.69"],["1IEP_B_STIB202_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;ALA A 617;MET A 641;PHE A 673;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","1.05A","1iepB-5td2A:28.9","1iepB-5td2A:41.69"],["1IEP_B_STIB202_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;MET A 641;PHE A 673;GLY A 677;ALA A 740","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 ( 3.7A)","0.87A","1iepB-5td2A:28.9","1iepB-5td2A:41.69"],["1Q23_G_FUAG708_1","CHLORAMPHENICOL ACETYLTRANSFERASE","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"PHE A 719;SER A 779;PHE A 847;VAL A 649;PHE A 644","None","1.38A","1q23G-5td2A:undetectable","1q23G-5td2A:20.89"],["1Q23_K_FUAK712_1","CHLORAMPHENICOL ACETYLTRANSFERASE","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"PHE A 719;SER A 779;PHE A 847;VAL A 649;PHE A 644","None","1.36A","1q23K-5td2A:undetectable","1q23K-5td2A:20.89"],["1T03_P_TFOP822_1","POL POLYPROTEIN;SYNTHETIC OLIGONUCLEOTIDE PRIMER","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"TYR A 676;MET A 735;ASP A 734;ASP A 733","None","1.47A","1t03A-5td2A:undetectable","1t03A-5td2A:20.31"],["2CEO_B_T44B1395_1","THYROXINE-BINDING GLOBULIN","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"ALA A 794;GLN A 853;LEU A 850;LEU A 854;LEU A 829","None","1.39A","2ceoB-5td2A:undetectable","2ceoB-5td2A:20.30"],["2DYR_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.91A","2dyrN-5td2A:2.4;2dyrW-5td2A:undetectable","2dyrN-5td2A:20.72;2dyrW-5td2A:15.20"],["2EIN_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.90A","2einN-5td2A:2.7;2einW-5td2A:undetectable","2einN-5td2A:20.72;2einW-5td2A:15.20"],["2HYY_A_STIA600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"VAL A 601;ALA A 617;MET A 641;PHE A 673;GLY A 677;ALA A 740","7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 ( 3.7A)","0.78A","2hyyA-5td2A:28.9","2hyyA-5td2A:43.25"],["2HYY_B_STIB600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"VAL A 601;ALA A 617;MET A 641;PHE A 673;GLY A 677;ALA A 740","7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 ( 3.7A)","0.75A","2hyyB-5td2A:29.2","2hyyB-5td2A:43.25"],["2ITY_A_IREA2020_1","EPIDERMAL GROWTH FACTOR RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",8,"LEU A 593;GLY A 594;VAL A 601;ALA A 617;LYS A 619;MET A 641;GLY A 677;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.2A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.1A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.83A","2ityA-5td2A:24.2","2ityA-5td2A:34.33"],["2WGJ_A_VGHA2346_1","HEPATOCYTE GROWTH FACTOR RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",9,"GLY A 594;VAL A 601;ALA A 617;LEU A 671;MET A 674;GLY A 677;MET A 730;ALA A 740;ASP A 741","7AE A1000 ( 4.2A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A);7AE A1000 (-3.6A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.49A","2wgjA-5td2A:30.9","2wgjA-5td2A:43.49"],["2XP2_A_VGHA9000_1","TYROSINE-PROTEIN KINASE RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;LEU A 671;MET A 674;GLY A 677;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.41A","2xp2A-5td2A:29.4","2xp2A-5td2A:37.74"],["3ABL_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.93A","3ablA-5td2A:2.8;3ablJ-5td2A:undetectable","3ablA-5td2A:20.72;3ablJ-5td2A:15.20"],["3AG1_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.98A","3ag1N-5td2A:3.2;3ag1W-5td2A:undetectable","3ag1N-5td2A:20.72;3ag1W-5td2A:15.20"],["3AOX_A_EMHA901_1","ALK TYROSINE KINASE RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;ALA A 617;LYS A 619;LEU A 671;MET A 674;GLY A 677","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);7AE A1000 (-3.1A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A)","0.47A","3aoxA-5td2A:11.8","3aoxA-5td2A:35.86"],["3CS9_A_NILA600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"ALA A 617;MET A 641;GLY A 677;PHE A 719;HIS A 721;ALA A 740","7AE A1000 (-3.3A);None;7AE A1000 ( 3.7A);None;None;7AE A1000 ( 3.7A)","0.75A","3cs9A-5td2A:29.5","3cs9A-5td2A:42.66"],["3CS9_B_NILB600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"ALA A 617;MET A 641;GLY A 677;HIS A 721;ALA A 740","7AE A1000 (-3.3A);None;7AE A1000 ( 3.7A);None;7AE A1000 ( 3.7A)","0.60A","3cs9B-5td2A:30.3","3cs9B-5td2A:42.66"],["3CS9_C_NILC600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"ALA A 617;MET A 641;PHE A 673;PHE A 719;HIS A 721;ALA A 740","7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);None;None;7AE A1000 ( 3.7A)","0.80A","3cs9C-5td2A:29.5","3cs9C-5td2A:42.66"],["3CS9_D_NILD600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"ALA A 617;MET A 641;GLY A 677;PHE A 719;HIS A 721;ALA A 740","7AE A1000 (-3.3A);None;7AE A1000 ( 3.7A);None;None;7AE A1000 ( 3.7A)","0.66A","3cs9D-5td2A:22.2","3cs9D-5td2A:42.66"],["3CS9_D_NILD600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"ALA A 617;MET A 641;PHE A 673;GLY A 677;HIS A 721;ALA A 740","7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);None;7AE A1000 ( 3.7A)","0.61A","3cs9D-5td2A:22.2","3cs9D-5td2A:42.66"],["3MIY_B_B49B2_1","TYROSINE-PROTEIN KINASE ITK\/TSK","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"ALA A 617;LYS A 619;PHE A 673;MET A 674;GLY A 677","7AE A1000 (-3.3A);7AE A1000 (-3.1A);7AE A1000 (-4.1A);None;7AE A1000 ( 3.7A)","0.55A","3miyB-5td2A:31.2","3miyB-5td2A:38.11"],["3MS9_A_STIA1_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;MET A 641;PHE A 673;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.98A","3ms9A-5td2A:29.1","3ms9A-5td2A:41.69"],["3MSS_A_STIA1_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;ALA A 617;MET A 641;PHE A 673;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.99A","3mssA-5td2A:29.3","3mssA-5td2A:41.69"],["3MSS_A_STIA1_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;VAL A 601;ALA A 617;MET A 641;PHE A 673;ALA A 740","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A)","0.75A","3mssA-5td2A:29.3","3mssA-5td2A:41.69"],["3MSS_C_STIC1_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;ALA A 617;MET A 641;PHE A 673;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","1.00A","3mssC-5td2A:29.4","3mssC-5td2A:41.69"],["3MSS_C_STIC1_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;VAL A 601;ALA A 617;MET A 641;PHE A 673;ALA A 740","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A)","0.75A","3mssC-5td2A:29.4","3mssC-5td2A:41.69"],["3MSS_D_STID1_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;ALA A 617;MET A 641;PHE A 673;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","1.00A","3mssD-5td2A:29.3","3mssD-5td2A:41.69"],["3MSS_D_STID1_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;ALA A 617;MET A 641;PHE A 673;GLY A 677;ALA A 740","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);None;7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 ( 3.7A)","0.84A","3mssD-5td2A:29.3","3mssD-5td2A:41.69"],["3V5W_A_8PRA701_2","G-PROTEIN COUPLED RECEPTOR KINASE 2","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",3,"LEU A 671;MET A 674;ASP A 678","7AE A1000 (-3.7A);None;7AE A1000 ( 4.8A)","0.63A","3v5wA-5td2A:10.0","3v5wA-5td2A:17.71"],["3WG7_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.98A","3wg7N-5td2A:undetectable;3wg7W-5td2A:undetectable","3wg7N-5td2A:20.72;3wg7W-5td2A:15.20"],["3WZE_A_BAXA1201_1","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",8,"LEU A 593;VAL A 601;ALA A 617;LYS A 619;PHE A 673;GLY A 677;LEU A 714;HIS A 721","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.1A);7AE A1000 (-4.1A);7AE A1000 ( 3.7A);None;None","0.67A","3wzeA-5td2A:29.4","3wzeA-5td2A:39.68"],["3ZBF_A_VGHA3000_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",8,"LEU A 593;ALA A 617;LEU A 671;MET A 674;GLY A 677;ASP A 678;THR A 681;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A);7AE A1000 ( 4.8A);None;7AE A1000 (-4.4A)","0.61A","3zbfA-5td2A:30.4","3zbfA-5td2A:40.25"],["4ANQ_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",8,"LEU A 593;VAL A 601;ALA A 617;LEU A 671;MET A 674;GLY A 677;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.52A","4anqA-5td2A:29.0","4anqA-5td2A:34.27"],["4ANS_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;MET A 674;GLY A 677;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 ( 3.7A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.57A","4ansA-5td2A:28.9","4ansA-5td2A:34.45"],["4ASD_A_BAXA1500_1","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",8,"LEU A 593;VAL A 601;ALA A 617;LYS A 619;PHE A 673;GLY A 677;LEU A 714;HIS A 721","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.1A);7AE A1000 (-4.1A);7AE A1000 ( 3.7A);None;None","0.72A","4asdA-5td2A:29.0","4asdA-5td2A:36.52"],["4IAA_A_RTZA401_1","SERINE\/THREONINE-PROTEIN KINASE PIM-1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"VAL A 601;ALA A 617;LYS A 619;LEU A 671;ASP A 678;ASP A 741","7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.1A);7AE A1000 (-3.7A);7AE A1000 ( 4.8A);7AE A1000 (-4.4A)","0.75A","4iaaA-5td2A:20.8","4iaaA-5td2A:25.55"],["4TWP_A_AXIA601_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",8,"VAL A 601;ALA A 617;PHE A 673;MET A 674;GLY A 677;ASN A 728;ALA A 740;ASP A 741","7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-4.1A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.7A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.60A","4twpA-5td2A:29.9","4twpA-5td2A:44.56"],["4TWP_B_AXIB601_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",9,"LEU A 593;VAL A 601;ALA A 617;PHE A 673;MET A 674;GLY A 677;ASN A 728;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-4.1A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.7A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.63A","4twpB-5td2A:16.9","4twpB-5td2A:44.56"],["4U5J_A_RXTA601_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",8,"LEU A 593;VAL A 601;ALA A 617;MET A 674;GLY A 677;ASN A 728;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.7A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.54A","4u5jA-5td2A:21.7","4u5jA-5td2A:38.13"],["4U5J_B_RXTB601_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;VAL A 601;ALA A 617;MET A 674;GLY A 677;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.71A","4u5jB-5td2A:21.5","4u5jB-5td2A:38.13"],["4V01_A_0LIA1776_1","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"ALA A 617;MET A 641;LEU A 714;HIS A 721;ALA A 740","7AE A1000 (-3.3A);None;None;None;7AE A1000 ( 3.7A)","0.71A","4v01A-5td2A:29.6","4v01A-5td2A:41.42"],["4V01_B_0LIB1770_1","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"ALA A 617;MET A 641;LEU A 714;HIS A 721;ALA A 740","7AE A1000 (-3.3A);None;None;None;7AE A1000 ( 3.7A)","0.59A","4v01B-5td2A:29.9","4v01B-5td2A:41.42"],["4WA9_A_AXIA9000_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",6,"LEU A 593;ALA A 617;MET A 674;GLY A 677;ASN A 728;ALA A 740","7AE A1000 ( 3.9A);7AE A1000 (-3.3A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.7A);7AE A1000 ( 3.7A)","0.71A","4wa9A-5td2A:27.8","4wa9A-5td2A:42.38"],["4WA9_B_AXIB9000_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"VAL A 601;ALA A 617;PHE A 673;MET A 674;GLY A 677;ASN A 728;ALA A 740","7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-4.1A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.7A);7AE A1000 ( 3.7A)","0.61A","4wa9B-5td2A:29.0","4wa9B-5td2A:42.38"],["5AAA_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;LEU A 671;MET A 674;GLY A 677;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.50A","5aaaA-5td2A:12.8","5aaaA-5td2A:38.05"],["5AAB_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;LEU A 671;MET A 674;GLY A 677;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.51A","5aabA-5td2A:21.1","5aabA-5td2A:38.05"],["5AAC_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;VAL A 601;ALA A 617;LEU A 671;MET A 674;GLY A 677;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 (-3.7A);None;7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","0.38A","5aacA-5td2A:21.2","5aacA-5td2A:37.74"],["5AJQ_A_DB8A800_1","SERINE\/THREONINE-PROTEIN KINASE 10","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",7,"LEU A 593;GLY A 594;ALA A 617;PHE A 673;GLY A 677;ALA A 740;ASP A 741","7AE A1000 ( 3.9A);7AE A1000 ( 4.2A);7AE A1000 (-3.3A);7AE A1000 (-4.1A);7AE A1000 ( 3.7A);7AE A1000 ( 3.7A);7AE A1000 (-4.4A)","1.04A","5ajqA-5td2A:17.8","5ajqA-5td2A:25.63"],["5G6S_F_RAUF400_1","IMINE REDUCTASE;IMINE REDUCTASE","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"GLY A 816;VAL A 788;LEU A 813;MET A 809;TYR A 812","None","1.46A","5g6sD-5td2A:1.5;5g6sF-5td2A:1.5","5g6sD-5td2A:23.24;5g6sF-5td2A:23.24"],["5IY5_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.93A","5iy5N-5td2A:undetectable;5iy5W-5td2A:undetectable","5iy5N-5td2A:20.72;5iy5W-5td2A:15.87"],["5XV7_A_EMHA705_1","SERINE-ARGININE (SR) PROTEIN KINASE 1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",5,"LEU A 593;GLY A 594;VAL A 601;ALA A 617;ALA A 740","7AE A1000 ( 3.9A);7AE A1000 ( 4.2A);7AE A1000 ( 4.9A);7AE A1000 (-3.3A);7AE A1000 ( 3.7A)","0.28A","5xv7A-5td2A:19.7","5xv7A-5td2A:14.08"],["5Z86_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.95A","5z86N-5td2A:undetectable;5z86W-5td2A:undetectable","5z86N-5td2A:20.72;5z86W-5td2A:15.20"],["5ZCO_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"ILE A 695;MET A 735;THR A 736;LEU A 731","None","0.97A","5zcoN-5td2A:2.8;5zcoW-5td2A:undetectable","5zcoN-5td2A:20.72;5zcoW-5td2A:15.20"],["6HD4_B_STIB602_1","TYROSINE-PROTEIN KINASE ABL1","5td2","TYROSINE-PROTEIN KINASE MER","Homo sapiens",4,"LEU A 593;PHE A 673;MET A 674;GLY A 677","7AE A1000 ( 3.9A);7AE A1000 (-4.1A);None;7AE A1000 ( 3.7A)","0.60A","6hd4B-5td2A:28.4","6hd4B-5td2A:12.93"]]