SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5td3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		3 / 3 GLU A 117
TYR A 121
PHE A 239
 None
 0.73A 1eqbB-5td3A:
undetectable		 1eqbB-5td3A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		3 / 3 GLU A 117
TYR A 121
PHE A 239
 None
 0.73A 1eqbA-5td3A:
undetectable		 1eqbA-5td3A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		3 / 3 GLU A 117
TYR A 121
PHE A 239
 None
 0.73A 1eqbD-5td3A:
undetectable		 1eqbD-5td3A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		3 / 3 GLU A 117
TYR A 121
PHE A 239
 None
 0.74A 1eqbC-5td3A:
undetectable		 1eqbC-5td3A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 GLY A  90
LEU A 120
LEU A  84
ALA A  83
THR A 115
 None
None
EDO  A 403 ( 4.6A)
None
None
 1.35A 1jipA-5td3A:
undetectable		 1jipA-5td3A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 TYR A 211
GLY A 230
ASP A 224
ALA A 265
GLY A 217
 None
 1.03A 1kiaB-5td3A:
undetectable		 1kiaB-5td3A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 TYR A 211
GLY A 230
ASP A 224
ALA A 265
GLY A 217
 None
 1.02A 1kiaC-5td3A:
undetectable		 1kiaC-5td3A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 TYR A 211
GLY A 230
ASP A 224
ALA A 265
GLY A 217
 None
 1.05A 1nbiA-5td3A:
undetectable		 1nbiA-5td3A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 TYR A 211
GLY A 230
ASP A 224
ALA A 265
GLY A 217
 None
 1.04A 1nbiB-5td3A:
undetectable		 1nbiB-5td3A:
24.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		8 / 11 LEU A  84
ILE A 116
GLY A 118
PRO A 119
TYR A 175
ARG A 232
HIS A 235
HIS A 237
 EDO  A 403 ( 4.6A)
None
None
None
ZN  A 401 (-4.2A)
ZN  A 401 ( 4.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.1A)
 0.61A 1s9aA-5td3A:
28.3		 1s9aA-5td3A:
30.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		9 / 12 LEU A  84
ILE A 116
GLY A 118
PRO A 119
TYR A 175
ARG A 232
HIS A 235
HIS A 237
GLN A 251
 EDO  A 403 ( 4.6A)
None
None
None
ZN  A 401 (-4.2A)
ZN  A 401 ( 4.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.1A)
ZN  A 401 ( 4.9A)
 0.45A 1s9aB-5td3A:
28.1		 1s9aB-5td3A:
30.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		6 / 11 GLY A 118
PRO A 119
TYR A 175
ARG A 232
HIS A 235
HIS A 237
 None
None
ZN  A 401 (-4.2A)
ZN  A 401 ( 4.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.1A)
 0.53A 1tmxA-5td3A:
27.8		 1tmxA-5td3A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		6 / 11 LEU A  84
GLY A 118
TYR A 175
ARG A 232
HIS A 235
HIS A 237
 EDO  A 403 ( 4.6A)
None
ZN  A 401 (-4.2A)
ZN  A 401 ( 4.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.1A)
 0.87A 1tmxA-5td3A:
27.8		 1tmxA-5td3A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		6 / 12 GLY A 118
PRO A 119
TYR A 175
ARG A 232
HIS A 235
HIS A 237
 None
None
ZN  A 401 (-4.2A)
ZN  A 401 ( 4.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.1A)
 0.42A 1tmxB-5td3A:
27.3		 1tmxB-5td3A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  84
GLY A 118
ARG A 232
HIS A 235
HIS A 237
 EDO  A 403 ( 4.6A)
None
ZN  A 401 ( 4.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.1A)
 0.85A 1tmxB-5td3A:
27.3		 1tmxB-5td3A:
30.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 PHE A 239
ALA A 265
PRO A 119
GLY A  88
TYR A 121
 None
 1.16A 2igtB-5td3A:
undetectable		 2igtB-5td3A:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 PHE A 239
ALA A 265
PRO A 119
GLY A  88
TYR A 121
 None
 1.13A 2igtC-5td3A:
undetectable		 2igtC-5td3A:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 GLY A 111
LEU A 248
LEU A 301
THR A 115
LEU A 272
 None
 1.06A 2nyuB-5td3A:
undetectable		 2nyuB-5td3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		3 / 3 ASP A 298
PHE A 299
LEU A 301
 None
 0.65A 2zi9A-5td3A:
undetectable		 2zi9A-5td3A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 THR A 250
THR A 115
HIS A 235
ILE A 147
TYR A 175
 None
None
ZN  A 401 (-3.2A)
None
ZN  A 401 (-4.2A)
 1.20A 3gwxA-5td3A:
undetectable		 3gwxA-5td3A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 THR A 250
THR A 115
HIS A 235
ILE A 295
TYR A 175
 None
None
ZN  A 401 (-3.2A)
None
ZN  A 401 (-4.2A)
 1.32A 3gwxA-5td3A:
undetectable		 3gwxA-5td3A:
21.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		8 / 12 LEU A  84
ILE A 116
GLY A 118
PRO A 119
TYR A 175
ARG A 232
HIS A 235
HIS A 237
 EDO  A 403 ( 4.6A)
None
None
None
ZN  A 401 (-4.2A)
ZN  A 401 ( 4.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.1A)
 0.52A 3hgiA-5td3A:
28.2		 3hgiA-5td3A:
30.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		4 / 6 ARG A 232
GLY A  88
GLU A  92
GLN A 220
 ZN  A 401 ( 4.7A)
None
None
None
 1.05A 4g0uA-5td3A:
undetectable		 4g0uA-5td3A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 8 PRO A 144
VAL A 146
GLY A 286
ALA A 283
GLY A 282
 None
 1.12A 4zjzA-5td3A:
undetectable		 4zjzA-5td3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		4 / 6 PHE A 299
SER A 242
ALA A 162
HIS A 245
 None
 1.26A 5dzkB-5td3A:
undetectable
5dzkP-5td3A:
undetectable		 5dzkB-5td3A:
22.92
5dzkP-5td3A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		4 / 6 PHE A 299
SER A 242
ALA A 162
HIS A 245
 None
 1.26A 5dzkg-5td3A:
undetectable
5dzku-5td3A:
undetectable		 5dzkg-5td3A:
22.92
5dzku-5td3A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 MET A  99
ASP A  96
LEU A  95
ASP A 309
THR A 241
 None
None
None
EDO  A 406 (-3.6A)
EDO  A 406 (-3.7A)
 1.26A 5tiwB-5td3A:
undetectable		 5tiwB-5td3A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		4 / 8 GLY A  90
ARG A 232
ASP A 263
ASP A  96
 None
ZN  A 401 ( 4.7A)
None
None
 0.97A 5vlmB-5td3A:
undetectable		 5vlmB-5td3A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 10 ASP A  96
LEU A  95
VAL A 313
ASP A 309
THR A 241
 None
None
None
EDO  A 406 (-3.6A)
EDO  A 406 (-3.7A)
 1.26A 6b4yA-5td3A:
undetectable		 6b4yA-5td3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 10 MET A  99
ASP A  96
LEU A  95
ASP A 309
THR A 241
 None
None
None
EDO  A 406 (-3.6A)
EDO  A 406 (-3.7A)
 1.41A 6b4yA-5td3A:
undetectable		 6b4yA-5td3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 ASP A  96
LEU A  95
VAL A 313
ASP A 309
THR A 241
 None
None
None
EDO  A 406 (-3.6A)
EDO  A 406 (-3.7A)
 1.26A 6b50A-5td3A:
undetectable		 6b50A-5td3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5td3 CATECHOL
1,2-DIOXYGENASE
(Burkholderia
vietnamiensis) 		5 / 12 MET A  99
ASP A  96
LEU A  95
ASP A 309
THR A 241
 None
None
None
EDO  A 406 (-3.6A)
EDO  A 406 (-3.7A)
 1.45A 6b50A-5td3A:
undetectable		 6b50A-5td3A:
20.73