SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5td6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		4 / 7 ILE A  89
ARG A 100
PHE A  98
PHE A  40
 None
 1.24A 1e71M-5td6A:
undetectable		 1e71M-5td6A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		4 / 6 ILE A  89
ARG A 100
PHE A  98
PHE A  40
 None
 1.22A 1e73M-5td6A:
undetectable		 1e73M-5td6A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		5 / 12 LEU A  84
VAL A  80
PHE A  28
VAL A  12
ALA A  67
 None
 1.06A 1q23H-5td6A:
undetectable
1q23I-5td6A:
undetectable		 1q23H-5td6A:
19.82
1q23I-5td6A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		4 / 6 HIS A  96
ARG A 100
ASN A  93
GLU A  53
 None
 1.07A 3galA-5td6A:
undetectable		 3galA-5td6A:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		4 / 6 HIS A  96
ARG A 100
ASN A  93
GLU A  53
 None
 1.18A 3galB-5td6A:
undetectable		 3galB-5td6A:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		5 / 11 PHE A  11
GLY A  33
LEU A  32
PHE A  40
ALA A  92
 None
 1.12A 4wnuC-5td6A:
undetectable		 4wnuC-5td6A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		4 / 7 HIS A  96
ARG A 100
ASN A  93
GLU A  53
 None
 1.12A 6b8kA-5td6A:
undetectable		 6b8kA-5td6A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		4 / 8 HIS A  96
ARG A 100
ASN A  93
GLU A  53
 None
 1.11A 6b94A-5td6A:
undetectable		 6b94A-5td6A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 5td6 FOG-3 PROTEIN
(Caenorhabditis
elegans) 		5 / 12 CYH A  13
PHE A  28
GLY A  29
LEU A  36
SER A  63
 None
 1.48A 6ci6A-5td6A:
1.7		 6ci6A-5td6A:
15.56