SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tdg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		4 / 8 SER A 287
SER A 248
TYR A 299
PHE A 237
 None
 1.16A 1eqbA-5tdgA:
undetectable
1eqbB-5tdgA:
undetectable		 1eqbA-5tdgA:
20.95
1eqbB-5tdgA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		4 / 8 TYR A 299
PHE A 237
SER A 287
SER A 248
 None
 1.19A 1eqbA-5tdgA:
undetectable
1eqbB-5tdgA:
undetectable		 1eqbA-5tdgA:
20.95
1eqbB-5tdgA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		4 / 8 SER A 287
SER A 248
TYR A 299
PHE A 237
 None
 1.17A 1eqbC-5tdgA:
undetectable
1eqbD-5tdgA:
undetectable		 1eqbC-5tdgA:
20.95
1eqbD-5tdgA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		4 / 8 TYR A 299
PHE A 237
SER A 287
SER A 248
 None
 1.19A 1eqbC-5tdgA:
undetectable
1eqbD-5tdgA:
undetectable		 1eqbC-5tdgA:
20.95
1eqbD-5tdgA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.77A 1grmA-5tdgA:
undetectable		 1grmA-5tdgA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.78A 1grmB-5tdgA:
undetectable		 1grmB-5tdgA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.85A 1jo3A-5tdgA:
undetectable		 1jo3A-5tdgA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.85A 1jo3B-5tdgA:
undetectable		 1jo3B-5tdgA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.81A 1jo4A-5tdgA:
undetectable		 1jo4A-5tdgA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.81A 1jo4B-5tdgA:
undetectable		 1jo4B-5tdgA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.91A 1ng8A-5tdgA:
undetectable		 1ng8A-5tdgA:
3.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.91A 1ng8B-5tdgA:
undetectable		 1ng8B-5tdgA:
3.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.89A 1nrmA-5tdgA:
undetectable		 1nrmA-5tdgA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.89A 1nrmB-5tdgA:
undetectable		 1nrmB-5tdgA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.91A 1nruA-5tdgA:
undetectable		 1nruA-5tdgA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 ALA A 529
VAL A 538
TRP A 537
 None
 0.91A 1nruB-5tdgA:
undetectable		 1nruB-5tdgA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		3 / 3 LYS A  70
LYS A  66
VAL A  68
 None
 1.03A 3brfA-5tdgA:
undetectable		 3brfA-5tdgA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		5 / 10 VAL A 187
LEU A 158
VAL A 300
VAL A 154
LEU A 181
 None
 1.03A 3gwxA-5tdgA:
undetectable		 3gwxA-5tdgA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		5 / 12 THR A 408
TYR A 441
ASP A 440
GLY A 438
TYR A 417
 None
 1.27A 3hiiB-5tdgA:
undetectable		 3hiiB-5tdgA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		5 / 12 THR A 189
VAL A  56
VAL A 300
ASN A 183
TYR A  53
 None
 1.26A 3nyaA-5tdgA:
undetectable		 3nyaA-5tdgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		4 / 7 LEU A 260
SER A 285
THR A 244
VAL A  57
 None
 1.04A 4wnvD-5tdgA:
undetectable		 4wnvD-5tdgA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		4 / 6 ALA A 298
THR A  58
VAL A 296
VAL A 179
 None
 1.04A 5eclA-5tdgA:
undetectable		 5eclA-5tdgA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5tdg FUSION GLYCOPROTEIN
F0,FIBRITIN
(Bovine
orthopneumovirus
;
Enterobacteria
phage
T4
sensu
lato) 		5 / 12 VAL A 308
THR A  50
VAL A 349
PHE A 352
VAL A 365
 None
 1.12A 6a94B-5tdgA:
undetectable		 6a94B-5tdgA:
21.85