SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5te1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 GLN A  26
TYR A  16
TRP A  49
GLN A  53
 None
 1.42A 1eiiA-5te1A:
undetectable		 1eiiA-5te1A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 11 ALA A 219
LEU A 217
LEU A 200
LEU A 188
ILE A  19
 None
 1.05A 1ha2A-5te1A:
undetectable		 1ha2A-5te1A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 6 PHE A 790
GLU A 669
LEU A 670
VAL A 714
 None
 1.01A 1hk1A-5te1A:
2.8		 1hk1A-5te1A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 9 GLY A 281
GLY A 665
GLY A 380
GLY A 381
ARG A 379
 7A2  A 901 ( 3.4A)
7A2  A 901 ( 3.4A)
None
None
7A2  A 901 (-2.9A)
 1.13A 1mxdA-5te1A:
2.0		 1mxdA-5te1A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 11 GLY A 281
GLY A 665
GLY A 380
GLY A 381
ARG A 379
 7A2  A 901 ( 3.4A)
7A2  A 901 ( 3.4A)
None
None
7A2  A 901 (-2.9A)
 1.12A 1mxgA-5te1A:
undetectable		 1mxgA-5te1A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 9 LEU A 217
VAL A 121
ILE A 185
GLY A 187
ILE A 202
 None
 1.02A 1ohrB-5te1A:
undetectable		 1ohrB-5te1A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 GLY A 808
ILE A 810
VAL A 811
PRO A 812
 None
 1.08A 1rxcL-5te1A:
undetectable		 1rxcL-5te1A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ILE A 727
GLY A 717
ALA A 772
VAL A 660
SER A 661
 None
 1.14A 1sg9C-5te1A:
4.6		 1sg9C-5te1A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 TYR A 659
THR A 593
THR A 619
SER A 695
 None
 1.20A 1tv8B-5te1A:
undetectable		 1tv8B-5te1A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 574
SER A 577
GLN A 505
TRP A 502
 None
 1.03A 2cmlB-5te1A:
undetectable		 2cmlB-5te1A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ILE A 414
LEU A 388
MET A 391
PHE A 354
ALA A 280
 None
None
None
None
7A2  A 901 ( 4.1A)
 0.93A 2jj8C-5te1A:
undetectable		 2jj8C-5te1A:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		3 / 3 TYR A 531
GLY A 535
PHE A 533
 None
 0.68A 2m2pB-5te1A:
undetectable		 2m2pB-5te1A:
3.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ILE A 745
GLY A 664
GLY A 283
THR A 639
VAL A 626
 None
7A2  A 901 (-4.0A)
PO4  A 902 (-3.5A)
None
7A2  A 901 ( 4.3A)
 1.12A 2okcA-5te1A:
4.4		 2okcA-5te1A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		3 / 3 GLY A 341
ARG A 379
TYR A 288
 None
7A2  A 901 (-2.9A)
None
 0.81A 2opxA-5te1A:
2.0		 2opxA-5te1A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 4 ALA A 351
VAL A 358
PHE A 354
THR A 316
 None
 1.49A 2pkkA-5te1A:
4.6		 2pkkA-5te1A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 THR A 639
ILE A 636
GLY A 637
ILE A 597
 None
 0.75A 2y7wC-5te1A:
undetectable		 2y7wC-5te1A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.42A 3ag1J-5te1A:
undetectable		 3ag1J-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 9 LEU A 217
VAL A 121
ILE A 185
GLY A 187
ILE A 202
 None
 1.14A 3ekqB-5te1A:
undetectable		 3ekqB-5te1A:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 9 LEU A 217
VAL A 121
ILE A 185
GLY A 187
ILE A 202
 None
 0.93A 3el0B-5te1A:
undetectable		 3el0B-5te1A:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 GLY A 664
GLU A 718
ALA A 763
ASP A 290
GLY A 746
 7A2  A 901 (-4.0A)
None
None
None
None
 1.42A 3jzjA-5te1A:
undetectable		 3jzjA-5te1A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 10 LEU A 217
VAL A 121
ILE A 185
GLY A 187
ILE A 202
 None
 0.96A 3oxwB-5te1A:
undetectable		 3oxwB-5te1A:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ARG A 378
ILE A 414
PHE A 354
ALA A 284
ALA A 345
 None
None
None
None
7A2  A 901 (-3.6A)
 1.31A 3ua1A-5te1A:
undetectable		 3ua1A-5te1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 10 ILE A 357
VAL A 350
ILE A 414
ILE A 340
TYR A 307
 None
 1.21A 3um5B-5te1A:
2.1		 3um5B-5te1A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 PHE A 493
VAL A 568
ILE A 591
GLU A 683
 None
 1.01A 4a97E-5te1A:
undetectable		 4a97E-5te1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 PHE A 493
VAL A 568
ILE A 591
GLU A 683
 None
 1.02A 4a97C-5te1A:
undetectable		 4a97C-5te1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 PHE A 493
VAL A 568
ILE A 591
GLU A 683
 None
 1.07A 4a97G-5te1A:
undetectable		 4a97G-5te1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 PHE A 493
VAL A 568
ILE A 591
GLU A 683
 None
 1.07A 4a97H-5te1A:
undetectable		 4a97H-5te1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 PHE A 493
VAL A 568
ILE A 591
GLU A 683
 None
 1.04A 4a97I-5te1A:
undetectable		 4a97I-5te1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ASN A 383
GLY A 380
GLY A 381
THR A 353
GLY A 665
 None
None
None
None
7A2  A 901 ( 3.4A)
 0.89A 4dc3B-5te1A:
3.3		 4dc3B-5te1A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 6 ILE A 673
ILE A 344
SER A 343
PHE A 790
 None
None
7A2  A 901 (-3.6A)
None
 0.85A 4m51A-5te1A:
undetectable		 4m51A-5te1A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 9 ILE A 620
GLY A 694
ILE A 687
ILE A 570
VAL A 568
 None
 1.13A 4nptA-5te1A:
undetectable		 4nptA-5te1A:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ASP A 290
VAL A 287
PHE A 758
GLY A 746
GLY A 282
 None
None
None
None
PO4  A 902 (-3.6A)
 1.40A 4pevB-5te1A:
8.2		 4pevB-5te1A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ALA A 345
SER A 343
ARG A 379
GLY A 342
GLU A 599
 7A2  A 901 (-3.6A)
7A2  A 901 (-3.6A)
7A2  A 901 (-2.9A)
None
None
 1.14A 4r29B-5te1A:
undetectable		 4r29B-5te1A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		6 / 12 ALA A 219
ILE A 228
VAL A 221
LEU A  14
ASP A 194
PHE A 191
 None
 1.29A 4tyjA-5te1A:
undetectable		 4tyjA-5te1A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 PHE A 697
GLY A 717
ILE A 687
LEU A 716
 None
 0.92A 5dzkd-5te1A:
3.1
5dzkk-5te1A:
undetectable
5dzky-5te1A:
undetectable		 5dzkd-5te1A:
15.28
5dzkk-5te1A:
14.20
5dzky-5te1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 6 ALA A 413
THR A 412
TYR A 288
HIS A 410
 None
 0.76A 5eckA-5te1A:
undetectable		 5eckA-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 6 ALA A 413
THR A 412
TYR A 288
HIS A 410
 None
 0.76A 5eckD-5te1A:
undetectable		 5eckD-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 6 ALA A 413
THR A 412
VAL A 415
TYR A 288
HIS A 410
 None
 1.42A 5eclA-5te1A:
0.9		 5eclA-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 ALA A 413
THR A 412
TYR A 288
HIS A 410
 None
 0.84A 5ecmA-5te1A:
undetectable		 5ecmA-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 7 ALA A 413
THR A 412
VAL A 415
GLU A 669
HIS A 410
 None
 1.43A 5ecmD-5te1A:
undetectable		 5ecmD-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 7 ALA A 413
THR A 412
VAL A 415
TYR A 288
HIS A 410
 None
 1.47A 5ecmD-5te1A:
undetectable		 5ecmD-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 ALA A 413
THR A 412
TYR A 288
GLU A 669
 None
 1.19A 5ecnA-5te1A:
undetectable		 5ecnA-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 6 ALA A 413
THR A 412
VAL A 415
TYR A 288
HIS A 410
 None
 1.36A 5ecoA-5te1A:
3.3		 5ecoA-5te1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 ARG A 662
HIS A 760
ALA A 761
ASP A 690
 None
PO4  A 902 (-3.9A)
None
None
 1.29A 5mfxA-5te1A:
undetectable		 5mfxA-5te1A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 10 LEU A 368
GLY A 335
LEU A 324
LEU A 338
THR A 374
 None
 1.04A 5o96G-5te1A:
3.0
5o96H-5te1A:
4.0		 5o96G-5te1A:
14.78
5o96H-5te1A:
14.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 4 THR A  38
ASP A  39
ARG A  42
LEU A  43
 None
 0.66A 5tdmA-5te1A:
36.3		 5tdmA-5te1A:
72.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 6 THR A  38
ASP A  39
ARG A  42
LEU A  43
ASP A  46
 None
 0.87A 5tdzA-5te1A:
36.9		 5tdzA-5te1A:
72.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.42A 5w97J-5te1A:
undetectable		 5w97J-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.42A 5wauJ-5te1A:
undetectable		 5wauJ-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.39A 5x19J-5te1A:
undetectable		 5x19J-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.37A 5x1bJ-5te1A:
undetectable		 5x1bJ-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.39A 5x1bW-5te1A:
undetectable		 5x1bW-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 HIS A 537
MET A 504
ASN A 555
VAL A 530
 None
 1.43A 5xdhB-5te1A:
1.0		 5xdhB-5te1A:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 TYR A 384
ASN A 672
LEU A 647
ALA A 648
 None
 0.82A 5y7pE-5te1A:
undetectable		 5y7pE-5te1A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		3 / 3 ARG A 359
LYS A 321
TYR A 364
 None
 1.07A 6gnaA-5te1A:
2.3		 6gnaA-5te1A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		3 / 3 ARG A 359
LYS A 321
TYR A 364
 None
 1.07A 6gnbA-5te1A:
2.3		 6gnbA-5te1A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 ALA A 578
THR A 582
ILE A 594
ALA A 595
 None
 0.89A 6ma7A-5te1A:
undetectable		 6ma7A-5te1A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		3 / 3 ARG A 521
PHE A 541
PHE A 634
 None
 1.02A 6nknC-5te1A:
undetectable
6nknJ-5te1A:
undetectable		 6nknC-5te1A:
15.31
6nknJ-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.42A 6nknJ-5te1A:
undetectable		 6nknJ-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 5 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.40A 6nknW-5te1A:
undetectable		 6nknW-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5te1 ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 11 GLY A 283
ALA A 345
ARG A 379
SER A 343
ALA A 280
 PO4  A 902 (-3.5A)
7A2  A 901 (-3.6A)
7A2  A 901 (-2.9A)
7A2  A 901 (-3.6A)
7A2  A 901 ( 4.1A)
 1.49A 6qgbA-5te1A:
4.2		 6qgbA-5te1A:
22.14