SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5te6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 5te6 LIGHT CHAIN OF N6
(Homo
sapiens) 		4 / 7 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.69A 1ictD-5te6L:
3.3		 1ictD-5te6L:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5te6 LIGHT CHAIN OF N6
(Homo
sapiens) 		4 / 5 LEU L 179
GLY L 128
PRO L 120
VAL L 132
 None
 0.91A 2aojA-5te6L:
undetectable		 2aojA-5te6L:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 5te6 HEAVY CHAIN OF N6
(Homo
sapiens) 		4 / 6 HIS H  32
ARG H   1
GLY H  26
LYS H   1
 None
 1.49A 2i30A-5te6H:
undetectable		 2i30A-5te6H:
18.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5te6 HEAVY CHAIN OF N6
LIGHT CHAIN OF N6
(Homo
sapiens;
Homo
sapiens) 		4 / 7 TYR H  91
TYR L  36
PRO L  44
TYR L  87
 None
 0.67A 2oldA-5te6H:
16.9
2oldB-5te6H:
17.4		 2oldA-5te6H:
31.30
2oldB-5te6H:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5te6 HEAVY CHAIN OF N6
LIGHT CHAIN OF N6
(Homo
sapiens;
Homo
sapiens) 		5 / 7 TYR L  36
HIS L  38
PRO L  44
TYR L  87
TYR H  91
 None
 0.64A 2oldA-5te6L:
15.9
2oldB-5te6L:
19.5		 2oldA-5te6L:
42.48
2oldB-5te6L:
42.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5te6 LIGHT CHAIN OF N6
(Homo
sapiens) 		4 / 7 TYR L  36
HIS L  38
PRO L  44
TYR L  87
 None
 0.68A 2ombC-5te6L:
16.9
2ombD-5te6L:
19.3		 2ombC-5te6L:
42.48
2ombD-5te6L:
42.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5te6 HEAVY CHAIN OF N6
LIGHT CHAIN OF N6
(Homo
sapiens;
Homo
sapiens) 		4 / 7 TYR L  36
HIS L  38
PRO L  44
TYR H  91
 None
 0.85A 2ombC-5te6L:
16.9
2ombD-5te6L:
19.3		 2ombC-5te6L:
42.48
2ombD-5te6L:
42.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5te6 HEAVY CHAIN OF N6
(Homo
sapiens) 		4 / 4 GLN H  53
PRO H  52
VAL H  73
GLU H  76
 None
 1.19A 3huoA-5te6H:
undetectable		 3huoA-5te6H:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5te6 HEAVY CHAIN OF N6
LIGHT CHAIN OF N6
(Homo
sapiens) 		4 / 5 SER L   9
ARG H  43
GLY H  44
GLU H  46
 None
 1.28A 3k9fA-5te6L:
undetectable
3k9fB-5te6L:
undetectable
3k9fC-5te6L:
undetectable		 3k9fA-5te6L:
16.90
3k9fB-5te6L:
16.90
3k9fC-5te6L:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5te6 LIGHT CHAIN OF N6
(Homo
sapiens) 		4 / 6 ASP L  32
GLY L  30
VAL L  29
THR L  51
 None
 1.00A 3vqrA-5te6L:
undetectable		 3vqrA-5te6L:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5te6 LIGHT CHAIN OF N6
(Homo
sapiens) 		4 / 5 ASP L  32
GLY L  30
VAL L  29
THR L  51
 None
 1.01A 3vqrB-5te6L:
undetectable		 3vqrB-5te6L:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 5te6 LIGHT CHAIN OF N6
(Homo
sapiens) 		4 / 7 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.97A 5bojB-5te6L:
undetectable		 5bojB-5te6L:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5te6 HEAVY CHAIN OF N6
(Homo
sapiens) 		4 / 4 GLY H  49
ARG H  64
ASN H  58
LEU H  69
 None
 0.99A 6b58A-5te6H:
undetectable		 6b58A-5te6H:
17.25