SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tea'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP2_B_PNNB5002_0 (TRANSCRIPTIONAL REGULATOR TCAR)	5tea	INORGANIC PYROPHOSPHATASE (Neisseria gonorrhoeae)	4 / 5	ALA A 89 ALA A 112 ARG A 90 LYS A 122	None	1.50A	3kp2B-5teaA: undetectable	3kp2B-5teaA: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KFJ_B_FOLB202_0 (DIHYDROFOLATE REDUCTASE)	5tea	INORGANIC PYROPHOSPHATASE (Neisseria gonorrhoeae)	5 / 12	ALA A 112 LEU A 87 ILE A 60 PRO A 61 VAL A 91	None	1.01A	4kfjB-5teaA: undetectable	4kfjB-5teaA: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BMV_C_VLBC507_1 (TUBULIN BETA CHAIN TUBULIN ALPHA-1B CHAIN)	5tea	INORGANIC PYROPHOSPHATASE (Neisseria gonorrhoeae)	4 / 6	ASP A 99 PRO A 54 TYR A 57 LEU A 74	None	1.26A	5bmvB-5teaA: undetectable	5bmvB-5teaA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KVA_B_SAMB301_1 (CAFFEOYL-COA O-METHYLTRANSFERASE)	5tea	INORGANIC PYROPHOSPHATASE (Neisseria gonorrhoeae)	3 / 3	THR A 63 SER A 169 ASP A 104	None None CA A 201 (-3.1A)	0.76A	5kvaB-5teaA: undetectable	5kvaB-5teaA: 22.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KP2_B_PNNB5002_0","TRANSCRIPTIONAL REGULATOR TCAR","5tea","INORGANIC PYROPHOSPHATASE","Neisseria gonorrhoeae",4,"ALA A  89;ALA A 112;ARG A  90;LYS A 122","None","1.50A","3kp2B-5teaA:undetectable","3kp2B-5teaA:21.83"],["4KFJ_B_FOLB202_0","DIHYDROFOLATE REDUCTASE","5tea","INORGANIC PYROPHOSPHATASE","Neisseria gonorrhoeae",5,"ALA A 112;LEU A  87;ILE A  60;PRO A  61;VAL A  91","None","1.01A","4kfjB-5teaA:undetectable","4kfjB-5teaA:23.72"],["5BMV_C_VLBC507_1","TUBULIN BETA CHAIN;TUBULIN ALPHA-1B CHAIN","5tea","INORGANIC PYROPHOSPHATASE","Neisseria gonorrhoeae",4,"ASP A  99;PRO A  54;TYR A  57;LEU A  74","None","1.26A","5bmvB-5teaA:undetectable","5bmvB-5teaA:18.30"],["5KVA_B_SAMB301_1","CAFFEOYL-COA O-METHYLTRANSFERASE","5tea","INORGANIC PYROPHOSPHATASE","Neisseria gonorrhoeae",3,"THR A  63;SER A 169;ASP A 104","None;None; CA A 201 (-3.1A)","0.76A","5kvaB-5teaA:undetectable","5kvaB-5teaA:22.46"]]