SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5teb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RK8_A_PPFA3969_1 (PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP])	5teb	RECOGNITION OF PERONOSPORA PARASITICA 1 (Arabidopsis thaliana)	4 / 8	HIS A 98 SER A 157 ASP A 101 ALA A 201	None	1.27A	2rk8A-5tebA: undetectable	2rk8A-5tebA: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CLB_B_TMQB612_1 (DHFR-TS)	5teb	RECOGNITION OF PERONOSPORA PARASITICA 1 (Arabidopsis thaliana)	5 / 12	ALA A 220 ILE A 168 THR A 181 PHE A 97 ILE A 191	None	0.99A	3clbB-5tebA: undetectable	3clbB-5tebA: 14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HBB_B_TMQB612_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5teb	RECOGNITION OF PERONOSPORA PARASITICA 1 (Arabidopsis thaliana)	5 / 9	ALA A 220 ILE A 168 THR A 181 PHE A 97 ILE A 191	None	0.96A	3hbbB-5tebA: undetectable	3hbbB-5tebA: 14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5teb	RECOGNITION OF PERONOSPORA PARASITICA 1 (Arabidopsis thaliana)	4 / 8	MET A 169 ILE A 168 VAL A 214 SER A 159	None	0.97A	6fbvC-5tebA: 1.4	6fbvC-5tebA: 9.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2RK8_A_PPFA3969_1","PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP]","5teb","RECOGNITION OF PERONOSPORA PARASITICA 1","Arabidopsis thaliana",4,"HIS A  98;SER A 157;ASP A 101;ALA A 201","None","1.27A","2rk8A-5tebA:undetectable","2rk8A-5tebA:15.15"],["3CLB_B_TMQB612_1","DHFR-TS","5teb","RECOGNITION OF PERONOSPORA PARASITICA 1","Arabidopsis thaliana",5,"ALA A 220;ILE A 168;THR A 181;PHE A  97;ILE A 191","None","0.99A","3clbB-5tebA:undetectable","3clbB-5tebA:14.62"],["3HBB_B_TMQB612_1","DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5teb","RECOGNITION OF PERONOSPORA PARASITICA 1","Arabidopsis thaliana",5,"ALA A 220;ILE A 168;THR A 181;PHE A  97;ILE A 191","None","0.96A","3hbbB-5tebA:undetectable","3hbbB-5tebA:14.62"],["6FBV_D_FI8D1904_0","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","5teb","RECOGNITION OF PERONOSPORA PARASITICA 1","Arabidopsis thaliana",4,"MET A 169;ILE A 168;VAL A 214;SER A 159","None","0.97A","6fbvC-5tebA:1.4","6fbvC-5tebA:9.82"]]