SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tet'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 6 PHE B 790
GLU B 669
LEU B 670
VAL B 714
 None
 0.92A 1hk1A-5tetB:
undetectable		 1hk1A-5tetB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 PHE B 790
GLU B 669
LEU B 670
VAL B 714
 None
 0.98A 1hk3A-5tetB:
undetectable		 1hk3A-5tetB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		5 / 12 ILE B 727
GLY B 717
ALA B 772
VAL B 660
SER B 661
 None
 1.12A 1sg9C-5tetB:
4.9		 1sg9C-5tetB:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 TYR B 659
THR B 593
THR B 619
SER B 695
 None
 1.19A 1tv8B-5tetB:
undetectable		 1tv8B-5tetB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 SER B 574
SER B 577
GLN B 505
TRP B 502
 None
 1.11A 2cmlA-5tetB:
undetectable		 2cmlA-5tetB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 SER B 574
SER B 577
GLN B 505
TRP B 502
 None
 1.03A 2cmlB-5tetB:
undetectable		 2cmlB-5tetB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		3 / 3 TYR B 531
GLY B 535
PHE B 533
 None
 0.71A 2m2pB-5tetB:
undetectable		 2m2pB-5tetB:
7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 THR B 639
ILE B 636
GLY B 637
ILE B 597
 None
 0.72A 2y7wC-5tetB:
undetectable		 2y7wC-5tetB:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 PHE B 493
VAL B 568
ILE B 591
GLU B 683
 None
 1.00A 4a97E-5tetB:
undetectable		 4a97E-5tetB:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 PHE B 493
VAL B 568
ILE B 591
GLU B 683
 None
 0.99A 4a97C-5tetB:
undetectable		 4a97C-5tetB:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 PHE B 493
VAL B 568
ILE B 591
GLU B 683
 None
 1.05A 4a97G-5tetB:
undetectable		 4a97G-5tetB:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 PHE B 493
VAL B 568
ILE B 591
GLU B 683
 None
 1.08A 4a97H-5tetB:
undetectable		 4a97H-5tetB:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 8 PHE B 493
VAL B 568
ILE B 591
GLU B 683
 None
 1.05A 4a97I-5tetB:
undetectable		 4a97I-5tetB:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 4 LEU B 702
LEU B 736
GLY B 730
GLU B 733
 None
 0.98A 5hhjA-5tetB:
undetectable		 5hhjA-5tetB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		4 / 7 ALA B 578
THR B 582
ILE B 594
ALA B 595
 None
 0.90A 6ma7A-5tetB:
undetectable		 6ma7A-5tetB:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tet ATP-CITRATE SYNTHASE
(Homo
sapiens) 		3 / 3 ARG B 521
PHE B 541
PHE B 634
 None
 0.99A 6nknC-5tetB:
undetectable
6nknJ-5tetB:
undetectable		 6nknC-5tetB:
21.30
6nknJ-5tetB:
14.24