SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tev'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 12 VAL A  90
LEU A  93
ASN A  94
ALA A 151
ILE A 146
 None
 0.69A 1fk6A-5tevA:
undetectable		 1fk6A-5tevA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 12 THR A 183
ILE A 170
ILE A 100
ILE A  87
ALA A 319
 None
 1.15A 1jtxA-5tevA:
undetectable		 1jtxA-5tevA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		4 / 7 GLY A 331
PHE A 174
ILE A  96
PHE A 182
 None
 1.03A 2qmzA-5tevA:
undetectable
2qmzB-5tevA:
undetectable		 2qmzA-5tevA:
20.98
2qmzB-5tevA:
20.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		7 / 10 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.41A 3fhjA-5tevA:
32.7		 3fhjA-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 10 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.08A 3fhjA-5tevA:
32.7		 3fhjA-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		7 / 10 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.41A 3fhjB-5tevA:
31.6		 3fhjB-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 10 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.08A 3fhjB-5tevA:
31.6		 3fhjB-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		7 / 10 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.40A 3fhjC-5tevA:
31.2		 3fhjC-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 10 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.08A 3fhjC-5tevA:
31.2		 3fhjC-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		7 / 9 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.41A 3fhjD-5tevA:
32.5		 3fhjD-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.08A 3fhjD-5tevA:
32.5		 3fhjD-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		7 / 10 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.41A 3fhjE-5tevA:
32.3		 3fhjE-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 10 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.08A 3fhjE-5tevA:
32.3		 3fhjE-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		7 / 9 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.41A 3fhjF-5tevA:
33.0		 3fhjF-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.08A 3fhjF-5tevA:
33.0		 3fhjF-5tevA:
33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
ASP A 145
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.02A 3fi0A-5tevA:
32.6		 3fi0A-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.44A 3fi0A-5tevA:
32.6		 3fi0A-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 8 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.40A 3fi0B-5tevA:
32.4		 3fi0B-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
ASP A 145
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.02A 3fi0C-5tevA:
32.5		 3fi0C-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.42A 3fi0C-5tevA:
32.5		 3fi0C-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ASP A 145
VAL A 154
VAL A 156
GLN A 160
 None
 1.05A 3fi0D-5tevA:
33.3		 3fi0D-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.45A 3fi0D-5tevA:
33.3		 3fi0D-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 7 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
 None
 0.30A 3fi0E-5tevA:
31.9		 3fi0E-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.46A 3fi0F-5tevA:
25.1		 3fi0F-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.06A 3fi0F-5tevA:
25.1		 3fi0F-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 8 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
 None
 0.31A 3fi0G-5tevA:
33.6		 3fi0G-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 8 GLY A   9
HIS A  47
ILE A 146
VAL A 154
VAL A 156
 None
 0.49A 3fi0G-5tevA:
33.6		 3fi0G-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.42A 3fi0H-5tevA:
33.3		 3fi0H-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.46A 3fi0J-5tevA:
26.1		 3fi0J-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.12A 3fi0J-5tevA:
26.1		 3fi0J-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.38A 3fi0K-5tevA:
32.4		 3fi0K-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.05A 3fi0K-5tevA:
32.4		 3fi0K-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.48A 3fi0L-5tevA:
33.2		 3fi0L-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ASP A 145
VAL A 154
VAL A 156
GLN A 160
 None
 1.07A 3fi0M-5tevA:
33.0		 3fi0M-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.41A 3fi0M-5tevA:
33.0		 3fi0M-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.47A 3fi0N-5tevA:
32.9		 3fi0N-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ILE A 146
VAL A 154
VAL A 156
GLN A 160
 None
 1.04A 3fi0N-5tevA:
32.9		 3fi0N-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 9 GLY A   9
ASP A 145
VAL A 154
VAL A 156
GLN A 160
 None
 1.14A 3fi0O-5tevA:
33.0		 3fi0O-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.48A 3fi0O-5tevA:
33.0		 3fi0O-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		4 / 7 GLY A   9
HIS A  47
ASP A 145
ILE A 146
 None
 0.27A 3fi0P-5tevA:
32.1		 3fi0P-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 8 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.42A 3fi0Q-5tevA:
33.2		 3fi0Q-5tevA:
33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
ASP A 145
ILE A 146
VAL A 154
VAL A 156
 None
 0.49A 3fi0R-5tevA:
31.5		 3fi0R-5tevA:
33.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 141
HIS A 163
PRO A 185
ILE A 146
HIS A 110
 None
 1.49A 5uhcC-5tevA:
undetectable		 5uhcC-5tevA:
14.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
 None
 0.23A 5v0iA-5tevA:
34.2		 5v0iA-5tevA:
33.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 5tev TRYPTOPHAN--TRNA
LIGASE
(Neisseria
gonorrhoeae) 		6 / 9 GLY A   9
HIS A  47
MET A 142
ASP A 145
ILE A 146
VAL A 154
 None
 0.20A 5v0iB-5tevA:
34.3		 5v0iB-5tevA:
33.98