SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tey'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_B_ADNB602_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	5 / 12	HIS B 287 GLU B 197 HIS A 482 LEU B 241 GLY B 238	None	1.23A	1d4fB-5teyB: undetectable	1d4fB-5teyB: 22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M4I_A_KANA500_1 (AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERA SE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	5 / 8	ASP A 453 GLU B 197 GLY B 236 THR B 272 ASP B 276	None	1.39A	1m4iA-5teyA: undetectable	1m4iA-5teyA: 14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M8E_B_H4BB903_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	1.04A	1m8eB-5teyA: undetectable	1m8eB-5teyA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	0.95A	1nodB-5teyA: undetectable	1nodB-5teyA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PJ7_A_FFOA2887_1 (N,N-DIMETHYLGLYCINE OXIDASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	3 / 3	ASP B 350 THR B 352 GLU B 192	None UNX B 406 ( 4.6A) None	0.87A	1pj7A-5teyB: undetectable	1pj7A-5teyB: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QOM_A_H4BA902_1 (NITRIC OXIDE SYNTHASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	0.83A	1qomA-5teyA: undetectable	1qomA-5teyA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HMY_B_SAMB328_0 (PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI))	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	5 / 12	PHE A 534 ASP A 377 ILE A 378 PRO A 397 LEU A 409	SAH A 601 (-4.7A) SAH A 601 (-3.2A) SAH A 601 (-3.9A) SAH A 601 (-4.3A) None	1.06A	2hmyB-5teyA: 5.2	2hmyB-5teyA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	0.98A	2nodB-5teyA: undetectable	2nodB-5teyA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRH_A_NIOA200_1 (PROTEIN HP0721)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	4 / 7	GLY A 387 ILE A 545 ARG A 529 LEU A 422	None	0.88A	2xrhA-5teyA: undetectable	2xrhA-5teyA: 13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E68_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	1.10A	3e68A-5teyA: undetectable	3e68A-5teyA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E6T_B_H4BB902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	1.02A	3e6tB-5teyA: undetectable	3e6tB-5teyA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E7I_B_H4BB2902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	0.89A	3e7iB-5teyA: undetectable	3e7iB-5teyA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EEO_A_SAMA328_0 (MODIFICATION METHYLASE HHAI)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	5 / 12	PHE A 534 ASP A 377 ILE A 378 PRO A 397 LEU A 409	SAH A 601 (-4.7A) SAH A 601 (-3.2A) SAH A 601 (-3.9A) SAH A 601 (-4.3A) None	0.99A	3eeoA-5teyA: 5.1	3eeoA-5teyA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H52_C_486C4_2 (GLUCOCORTICOID RECEPTOR)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	MET A 520 CYH A 483 PRO A 514	None	0.62A	3h52C-5teyA: undetectable	3h52C-5teyA: 18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NW2_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	0.96A	3nw2A-5teyA: undetectable	3nw2A-5teyA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NW2_B_H4BB902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 508 ILE A 503 TRP A 457	None	0.90A	3nw2B-5teyA: undetectable	3nw2B-5teyA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P5N_B_RBFB190_2 (RIBOFLAVIN UPTAKE PROTEIN)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	4 / 4	LYS B 278 TYR A 449 ASN A 490 PHE A 427	None	1.30A	3p5nB-5teyB: undetectable	3p5nB-5teyB: 17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ6_A_SAMA300_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	5 / 12	TYR A 518 ILE A 517 ILE A 521 ASP A 395 LEU A 547	None None None SAH A 601 (-3.8A) None	0.95A	3uj6A-5teyA: undetectable	3uj6A-5teyA: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FUK_A_SNPA1236_1 (MROUPO)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	4 / 7	ILE A 456 ILE B 315 THR A 460 ILE A 466	None	0.65A	5fukA-5teyA: undetectable 5fukB-5teyA: undetectable	5fukA-5teyA: 17.54 5fukB-5teyA: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_A_SAMA301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	5 / 12	ASP A 377 ASP A 395 PRO A 397 PHE A 534 GLY A 535	SAH A 601 (-3.2A) SAH A 601 (-3.8A) SAH A 601 (-4.3A) SAH A 601 (-4.7A) SAH A 601 ( 4.6A)	0.88A	5hfjA-5teyA: 13.7	5hfjA-5teyA: 16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_H_SAMH301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	5 / 12	ASP A 377 ASP A 395 PRO A 397 LYS A 513 GLY A 535	SAH A 601 (-3.2A) SAH A 601 (-3.8A) SAH A 601 (-4.3A) SAH A 601 (-4.9A) SAH A 601 ( 4.6A)	0.91A	5hfjH-5teyA: 14.0	5hfjH-5teyA: 16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_H_SAMH301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	5 / 12	ASP A 377 ASP A 395 PRO A 397 LYS A 513 PHE A 534	SAH A 601 (-3.2A) SAH A 601 (-3.8A) SAH A 601 (-4.3A) SAH A 601 (-4.9A) SAH A 601 (-4.7A)	0.59A	5hfjH-5teyA: 14.0	5hfjH-5teyA: 16.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5IL1_A_SAMA601_0 (METTL3)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	10 / 12	ASP A 377 ILE A 378 ARG A 379 PRO A 397 LEU A 409 LYS A 513 GLU A 532 PHE A 534 ASN A 539 GLY A 548	SAH A 601 (-3.2A) SAH A 601 (-3.9A) SAH A 601 ( 4.7A) SAH A 601 (-4.3A) None SAH A 601 (-4.9A) SAH A 601 ( 4.9A) SAH A 601 (-4.7A) SAH A 601 (-3.1A) SAH A 601 ( 3.8A)	0.16A	5il1A-5teyA: 32.0	5il1A-5teyA: 99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5IL1_A_SAMA601_0 (METTL3)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	10 / 12	ASP A 377 ILE A 378 ARG A 379 PRO A 397 LEU A 409 SER A 511 LYS A 513 GLU A 532 PHE A 534 GLY A 548	SAH A 601 (-3.2A) SAH A 601 (-3.9A) SAH A 601 ( 4.7A) SAH A 601 (-4.3A) None SAH A 601 (-4.6A) SAH A 601 (-4.9A) SAH A 601 ( 4.9A) SAH A 601 (-4.7A) SAH A 601 ( 3.8A)	0.52A	5il1A-5teyA: 32.0	5il1A-5teyA: 99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5IL1_A_SAMA601_0 (METTL3)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	7 / 12	ILE A 378 PRO A 397 LEU A 409 GLU A 532 PHE A 534 ARG A 536 ASN A 539	SAH A 601 (-3.9A) SAH A 601 (-4.3A) None SAH A 601 ( 4.9A) SAH A 601 (-4.7A) SAH A 601 (-3.7A) SAH A 601 (-3.1A)	0.96A	5il1A-5teyA: 32.0	5il1A-5teyA: 99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5IL1_A_SAMA601_0 (METTL3)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	7 / 12	ILE A 378 PRO A 397 LEU A 409 SER A 511 GLU A 532 PHE A 534 ARG A 536	SAH A 601 (-3.9A) SAH A 601 (-4.3A) None SAH A 601 (-4.6A) SAH A 601 ( 4.9A) SAH A 601 (-4.7A) SAH A 601 (-3.7A)	1.16A	5il1A-5teyA: 32.0	5il1A-5teyA: 99.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IL1_A_SAMA601_0 (METTL3)	5tey	N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	6 / 12	ASP B 173 ILE B 174 PRO B 194 LYS B 326 PHE B 347 GLY B 361	None UNX B 407 ( 4.2A) None None None None	1.16A	5il1A-5teyB: 19.9	5il1A-5teyB: 20.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5K7U_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	12 / 12	ASP A 377 ILE A 378 ARG A 379 PRO A 397 LEU A 409 LYS A 513 GLU A 532 PHE A 534 ARG A 536 HIS A 538 ASN A 539 GLY A 548	SAH A 601 (-3.2A) SAH A 601 (-3.9A) SAH A 601 ( 4.7A) SAH A 601 (-4.3A) None SAH A 601 (-4.9A) SAH A 601 ( 4.9A) SAH A 601 (-4.7A) SAH A 601 (-3.7A) SAH A 601 (-4.0A) SAH A 601 (-3.1A) SAH A 601 ( 3.8A)	0.42A	5k7uA-5teyA: 32.5	5k7uA-5teyA: 37.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K7U_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5tey	N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	6 / 12	ASP B 173 ILE B 174 PRO B 194 LYS B 326 PHE B 347 GLY B 361	None UNX B 407 ( 4.2A) None None None None	1.16A	5k7uA-5teyB: 19.8	5k7uA-5teyB: 21.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5K7U_A_SAMA601_1 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ASP A 395 ASN A 549 GLN A 550	SAH A 601 (-3.8A) SAH A 601 (-3.1A) SAH A 601 (-3.7A)	0.14A	5k7uA-5teyA: 32.5	5k7uA-5teyA: 37.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KXI_A_NCTA402_1 (NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4 NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	4 / 8	THR A 410 CYH A 443 TRP A 398 LEU A 439	None	1.32A	5kxiA-5teyA: undetectable 5kxiB-5teyA: undetectable	5kxiA-5teyA: 20.87 5kxiB-5teyA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KXI_D_NCTD402_1 (NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4 NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	4 / 8	THR A 410 CYH A 443 TRP A 398 LEU A 439	None	1.31A	5kxiD-5teyA: undetectable 5kxiE-5teyA: undetectable	5kxiD-5teyA: 20.87 5kxiE-5teyA: 19.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L6E_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	12 / 12	ILE A 378 ARG A 379 PRO A 397 LEU A 409 SER A 511 HIS A 512 LYS A 513 GLU A 532 PHE A 534 GLY A 535 HIS A 538 GLY A 548	SAH A 601 (-3.9A) SAH A 601 ( 4.7A) SAH A 601 (-4.3A) None SAH A 601 (-4.6A) SAH A 601 (-4.6A) SAH A 601 (-4.9A) SAH A 601 ( 4.9A) SAH A 601 (-4.7A) SAH A 601 ( 4.6A) SAH A 601 (-4.0A) SAH A 601 ( 3.8A)	0.06A	5l6eA-5teyA: 36.0	5l6eA-5teyA: 99.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L6E_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5tey	N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	6 / 12	ILE B 174 PRO B 194 LYS B 326 PHE B 347 GLY B 348 GLY B 361	UNX B 407 ( 4.2A) None None None None None	0.79A	5l6eA-5teyB: 19.9	5l6eA-5teyB: 21.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L6E_A_SAMA601_1 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	6 / 6	ASP A 377 ASP A 395 ARG A 536 ASN A 539 ASN A 549 GLN A 550	SAH A 601 (-3.2A) SAH A 601 (-3.8A) SAH A 601 (-3.7A) SAH A 601 (-3.1A) SAH A 601 (-3.1A) SAH A 601 (-3.7A)	0.14A	5l6eA-5teyA: 36.0	5l6eA-5teyA: 99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L6E_B_ACTB401_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens; Homo sapiens)	5 / 6	GLU A 438 ARG B 245 LEU B 248 ARG B 249 ARG B 255	UNX B 405 ( 4.5A) None None UNX B 405 ( 4.8A) None	0.22A	5l6eA-5teyA: 36.0 5l6eB-5teyA: 20.7	5l6eA-5teyA: 99.56 5l6eB-5teyA: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVM_A_PFLA511_1 (PROTON-GATED ION CHANNEL)	5tey	N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	4 / 8	ILE B 189 ALA B 225 ILE B 224 TYR B 253	None	0.77A	5mvmA-5teyB: undetectable 5mvmB-5teyB: undetectable	5mvmA-5teyB: 11.03 5mvmB-5teyB: 11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NY7_A_NCAA303_0 (AMIDASE)	5tey	N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	4 / 6	ARG B 354 GLY B 356 PRO B 355 GLU B 335	UNX B 404 ( 4.0A) None None None	0.78A	5ny7A-5teyB: undetectable	5ny7A-5teyB: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5tey	N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT (Homo sapiens)	3 / 3	ARG A 441 LEU A 484 PHE A 429	None	0.68A	6nknP-5teyA: undetectable	6nknP-5teyA: 16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5tey	N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14 (Homo sapiens)	3 / 3	ARG B 245 LEU B 289 PHE B 232	None	0.71A	6nknP-5teyB: undetectable	6nknP-5teyB: 19.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D4F_B_ADNB602_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",5,"HIS B 287;GLU B 197;HIS A 482;LEU B 241;GLY B 238","None","1.23A","1d4fB-5teyB:undetectable","1d4fB-5teyB:22.67"],["1M4I_A_KANA500_1","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",5,"ASP A 453;GLU B 197;GLY B 236;THR B 272;ASP B 276","None","1.39A","1m4iA-5teyA:undetectable","1m4iA-5teyA:14.89"],["1M8E_B_H4BB903_1","INDUCIBLE NITRIC OXIDE SYNTHASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","1.04A","1m8eB-5teyA:undetectable","1m8eB-5teyA:20.42"],["1NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","0.95A","1nodB-5teyA:undetectable","1nodB-5teyA:20.75"],["1PJ7_A_FFOA2887_1","N,N-DIMETHYLGLYCINE OXIDASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",3,"ASP B 350;THR B 352;GLU B 192","None;UNX B 406 ( 4.6A);None","0.87A","1pj7A-5teyB:undetectable","1pj7A-5teyB:18.23"],["1QOM_A_H4BA902_1","NITRIC OXIDE SYNTHASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","0.83A","1qomA-5teyA:undetectable","1qomA-5teyA:20.42"],["2HMY_B_SAMB328_0","PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI)","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",5,"PHE A 534;ASP A 377;ILE A 378;PRO A 397;LEU A 409","SAH A 601 (-4.7A);SAH A 601 (-3.2A);SAH A 601 (-3.9A);SAH A 601 (-4.3A);None","1.06A","2hmyB-5teyA:5.2","2hmyB-5teyA:19.17"],["2NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","0.98A","2nodB-5teyA:undetectable","2nodB-5teyA:20.75"],["2XRH_A_NIOA200_1","PROTEIN HP0721","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",4,"GLY A 387;ILE A 545;ARG A 529;LEU A 422","None","0.88A","2xrhA-5teyA:undetectable","2xrhA-5teyA:13.96"],["3E68_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","1.10A","3e68A-5teyA:undetectable","3e68A-5teyA:20.77"],["3E6T_B_H4BB902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","1.02A","3e6tB-5teyA:undetectable","3e6tB-5teyA:20.77"],["3E7I_B_H4BB2902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","0.89A","3e7iB-5teyA:undetectable","3e7iB-5teyA:20.77"],["3EEO_A_SAMA328_0","MODIFICATION METHYLASE HHAI","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",5,"PHE A 534;ASP A 377;ILE A 378;PRO A 397;LEU A 409","SAH A 601 (-4.7A);SAH A 601 (-3.2A);SAH A 601 (-3.9A);SAH A 601 (-4.3A);None","0.99A","3eeoA-5teyA:5.1","3eeoA-5teyA:19.17"],["3H52_C_486C4_2","GLUCOCORTICOID RECEPTOR","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"MET A 520;CYH A 483;PRO A 514","None","0.62A","3h52C-5teyA:undetectable","3h52C-5teyA:18.17"],["3NW2_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","0.96A","3nw2A-5teyA:undetectable","3nw2A-5teyA:20.75"],["3NW2_B_H4BB902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 508;ILE A 503;TRP A 457","None","0.90A","3nw2B-5teyA:undetectable","3nw2B-5teyA:20.75"],["3P5N_B_RBFB190_2","RIBOFLAVIN UPTAKE PROTEIN","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",4,"LYS B 278;TYR A 449;ASN A 490;PHE A 427","None","1.30A","3p5nB-5teyB:undetectable","3p5nB-5teyB:17.29"],["3UJ6_A_SAMA300_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",5,"TYR A 518;ILE A 517;ILE A 521;ASP A 395;LEU A 547","None;None;None;SAH A 601 (-3.8A);None","0.95A","3uj6A-5teyA:undetectable","3uj6A-5teyA:19.10"],["5FUK_A_SNPA1236_1","MROUPO;MROUPO","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",4,"ILE A 456;ILE B 315;THR A 460;ILE A 466","None","0.65A","5fukA-5teyA:undetectable;5fukB-5teyA:undetectable","5fukA-5teyA:17.54;5fukB-5teyA:17.54"],["5HFJ_A_SAMA301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",5,"ASP A 377;ASP A 395;PRO A 397;PHE A 534;GLY A 535","SAH A 601 (-3.2A);SAH A 601 (-3.8A);SAH A 601 (-4.3A);SAH A 601 (-4.7A);SAH A 601 ( 4.6A)","0.88A","5hfjA-5teyA:13.7","5hfjA-5teyA:16.76"],["5HFJ_H_SAMH301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",5,"ASP A 377;ASP A 395;PRO A 397;LYS A 513;GLY A 535","SAH A 601 (-3.2A);SAH A 601 (-3.8A);SAH A 601 (-4.3A);SAH A 601 (-4.9A);SAH A 601 ( 4.6A)","0.91A","5hfjH-5teyA:14.0","5hfjH-5teyA:16.76"],["5HFJ_H_SAMH301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",5,"ASP A 377;ASP A 395;PRO A 397;LYS A 513;PHE A 534","SAH A 601 (-3.2A);SAH A 601 (-3.8A);SAH A 601 (-4.3A);SAH A 601 (-4.9A);SAH A 601 (-4.7A)","0.59A","5hfjH-5teyA:14.0","5hfjH-5teyA:16.76"],["5IL1_A_SAMA601_0","METTL3","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",10,"ASP A 377;ILE A 378;ARG A 379;PRO A 397;LEU A 409;LYS A 513;GLU A 532;PHE A 534;ASN A 539;GLY A 548","SAH A 601 (-3.2A);SAH A 601 (-3.9A);SAH A 601 ( 4.7A);SAH A 601 (-4.3A);None;SAH A 601 (-4.9A);SAH A 601 ( 4.9A);SAH A 601 (-4.7A);SAH A 601 (-3.1A);SAH A 601 ( 3.8A)","0.16A","5il1A-5teyA:32.0","5il1A-5teyA:99.53"],["5IL1_A_SAMA601_0","METTL3","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",10,"ASP A 377;ILE A 378;ARG A 379;PRO A 397;LEU A 409;SER A 511;LYS A 513;GLU A 532;PHE A 534;GLY A 548","SAH A 601 (-3.2A);SAH A 601 (-3.9A);SAH A 601 ( 4.7A);SAH A 601 (-4.3A);None;SAH A 601 (-4.6A);SAH A 601 (-4.9A);SAH A 601 ( 4.9A);SAH A 601 (-4.7A);SAH A 601 ( 3.8A)","0.52A","5il1A-5teyA:32.0","5il1A-5teyA:99.53"],["5IL1_A_SAMA601_0","METTL3","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",7,"ILE A 378;PRO A 397;LEU A 409;GLU A 532;PHE A 534;ARG A 536;ASN A 539","SAH A 601 (-3.9A);SAH A 601 (-4.3A);None;SAH A 601 ( 4.9A);SAH A 601 (-4.7A);SAH A 601 (-3.7A);SAH A 601 (-3.1A)","0.96A","5il1A-5teyA:32.0","5il1A-5teyA:99.53"],["5IL1_A_SAMA601_0","METTL3","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",7,"ILE A 378;PRO A 397;LEU A 409;SER A 511;GLU A 532;PHE A 534;ARG A 536","SAH A 601 (-3.9A);SAH A 601 (-4.3A);None;SAH A 601 (-4.6A);SAH A 601 ( 4.9A);SAH A 601 (-4.7A);SAH A 601 (-3.7A)","1.16A","5il1A-5teyA:32.0","5il1A-5teyA:99.53"],["5IL1_A_SAMA601_0","METTL3","5tey","N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",6,"ASP B 173;ILE B 174;PRO B 194;LYS B 326;PHE B 347;GLY B 361","None;UNX B 407 ( 4.2A);None;None;None;None","1.16A","5il1A-5teyB:19.9","5il1A-5teyB:20.76"],["5K7U_A_SAMA601_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",12,"ASP A 377;ILE A 378;ARG A 379;PRO A 397;LEU A 409;LYS A 513;GLU A 532;PHE A 534;ARG A 536;HIS A 538;ASN A 539;GLY A 548","SAH A 601 (-3.2A);SAH A 601 (-3.9A);SAH A 601 ( 4.7A);SAH A 601 (-4.3A);None;SAH A 601 (-4.9A);SAH A 601 ( 4.9A);SAH A 601 (-4.7A);SAH A 601 (-3.7A);SAH A 601 (-4.0A);SAH A 601 (-3.1A);SAH A 601 ( 3.8A)","0.42A","5k7uA-5teyA:32.5","5k7uA-5teyA:37.46"],["5K7U_A_SAMA601_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5tey","N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",6,"ASP B 173;ILE B 174;PRO B 194;LYS B 326;PHE B 347;GLY B 361","None;UNX B 407 ( 4.2A);None;None;None;None","1.16A","5k7uA-5teyB:19.8","5k7uA-5teyB:21.01"],["5K7U_A_SAMA601_1","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ASP A 395;ASN A 549;GLN A 550","SAH A 601 (-3.8A);SAH A 601 (-3.1A);SAH A 601 (-3.7A)","0.14A","5k7uA-5teyA:32.5","5k7uA-5teyA:37.46"],["5KXI_A_NCTA402_1","NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4;NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",4,"THR A 410;CYH A 443;TRP A 398;LEU A 439","None","1.32A","5kxiA-5teyA:undetectable;5kxiB-5teyA:undetectable","5kxiA-5teyA:20.87;5kxiB-5teyA:19.67"],["5KXI_D_NCTD402_1","NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4;NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",4,"THR A 410;CYH A 443;TRP A 398;LEU A 439","None","1.31A","5kxiD-5teyA:undetectable;5kxiE-5teyA:undetectable","5kxiD-5teyA:20.87;5kxiE-5teyA:19.67"],["5L6E_A_SAMA601_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",12,"ILE A 378;ARG A 379;PRO A 397;LEU A 409;SER A 511;HIS A 512;LYS A 513;GLU A 532;PHE A 534;GLY A 535;HIS A 538;GLY A 548","SAH A 601 (-3.9A);SAH A 601 ( 4.7A);SAH A 601 (-4.3A);None;SAH A 601 (-4.6A);SAH A 601 (-4.6A);SAH A 601 (-4.9A);SAH A 601 ( 4.9A);SAH A 601 (-4.7A);SAH A 601 ( 4.6A);SAH A 601 (-4.0A);SAH A 601 ( 3.8A)","0.06A","5l6eA-5teyA:36.0","5l6eA-5teyA:99.56"],["5L6E_A_SAMA601_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5tey","N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",6,"ILE B 174;PRO B 194;LYS B 326;PHE B 347;GLY B 348;GLY B 361","UNX B 407 ( 4.2A);None;None;None;None;None","0.79A","5l6eA-5teyB:19.9","5l6eA-5teyB:21.52"],["5L6E_A_SAMA601_1","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",6,"ASP A 377;ASP A 395;ARG A 536;ASN A 539;ASN A 549;GLN A 550","SAH A 601 (-3.2A);SAH A 601 (-3.8A);SAH A 601 (-3.7A);SAH A 601 (-3.1A);SAH A 601 (-3.1A);SAH A 601 (-3.7A)","0.14A","5l6eA-5teyA:36.0","5l6eA-5teyA:99.56"],["5L6E_B_ACTB401_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens;Homo sapiens",5,"GLU A 438;ARG B 245;LEU B 248;ARG B 249;ARG B 255","UNX B 405 ( 4.5A);None;None;UNX B 405 ( 4.8A);None","0.22A","5l6eA-5teyA:36.0;5l6eB-5teyA:20.7","5l6eA-5teyA:99.56;5l6eB-5teyA:18.23"],["5MVM_A_PFLA511_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","5tey","N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",4,"ILE B 189;ALA B 225;ILE B 224;TYR B 253","None","0.77A","5mvmA-5teyB:undetectable;5mvmB-5teyB:undetectable","5mvmA-5teyB:11.03;5mvmB-5teyB:11.03"],["5NY7_A_NCAA303_0","AMIDASE","5tey","N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",4,"ARG B 354;GLY B 356;PRO B 355;GLU B 335","UNX B 404 ( 4.0A);None;None;None","0.78A","5ny7A-5teyB:undetectable","5ny7A-5teyB:20.88"],["6NKN_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5tey","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","Homo sapiens",3,"ARG A 441;LEU A 484;PHE A 429","None","0.68A","6nknP-5teyA:undetectable","6nknP-5teyA:16.23"],["6NKN_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5tey","N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","Homo sapiens",3,"ARG B 245;LEU B 289;PHE B 232","None","0.71A","6nknP-5teyB:undetectable","6nknP-5teyB:19.75"]]