SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 TRP A 566
ARG A 560
THR A 565
None
0.95A 1df7A-5tf0A:
1.3
1df7A-5tf0A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 4 VAL A 171
TRP A 437
TRP A 168
None
1.30A 1gmkA-5tf0A:
undetectable
1gmkB-5tf0A:
undetectable
1gmkA-5tf0A:
1.58
1gmkB-5tf0A:
1.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 4 VAL A 171
TRP A 437
TRP A 168
None
1.27A 1gmkC-5tf0A:
undetectable
1gmkD-5tf0A:
undetectable
1gmkC-5tf0A:
1.58
1gmkD-5tf0A:
1.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 169
GLY A 176
LEU A 125
SER A 163
GLY A 174
None
1.12A 1jhoA-5tf0A:
2.4
1jhoA-5tf0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 169
GLY A 176
LEU A 125
SER A 163
GLY A 174
None
1.16A 1jhrA-5tf0A:
2.1
1jhrA-5tf0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 7 LEU A 107
LEU A  84
LEU A  96
GLN A  94
None
1.10A 1kt3A-5tf0A:
undetectable
1kt3A-5tf0A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 169
GLY A 176
LEU A 125
SER A 163
GLY A 174
None
1.14A 1l5kA-5tf0A:
undetectable
1l5kA-5tf0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 169
GLY A 176
LEU A 125
SER A 163
GLY A 174
None
1.13A 1l5lA-5tf0A:
undetectable
1l5lA-5tf0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 169
GLY A 176
LEU A 125
SER A 163
GLY A 174
None
1.14A 1l5mA-5tf0A:
0.5
1l5mA-5tf0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 6 LEU A  51
ASP A 320
GLY A 287
ARG A 280
None
0.77A 1mt1G-5tf0A:
undetectable
1mt1J-5tf0A:
undetectable
1mt1G-5tf0A:
6.25
1mt1J-5tf0A:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 6 ARG A 280
LEU A  51
ASP A 320
GLY A 287
None
0.80A 1n13H-5tf0A:
undetectable
1n13K-5tf0A:
undetectable
1n13H-5tf0A:
9.31
1n13K-5tf0A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 7 LEU A  51
ASP A 320
GLY A 287
ARG A 280
None
0.81A 1n13G-5tf0A:
undetectable
1n13J-5tf0A:
undetectable
1n13G-5tf0A:
6.25
1n13J-5tf0A:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 ARG A 708
ASP A 178
ASN A 175
None
0.95A 1nbhA-5tf0A:
undetectable
1nbhA-5tf0A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 ARG A 708
ASP A 178
ASN A 175
None
0.94A 1nbhD-5tf0A:
undetectable
1nbhD-5tf0A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLU A 355
ASP A 320
GLY A 287
ARG A 280
ASP A 286
None
1.38A 1oltA-5tf0A:
undetectable
1oltA-5tf0A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 TYR A 698
ILE A 758
GLY A 759
GLY A 651
VAL A 681
None
1.08A 1vptA-5tf0A:
undetectable
1vptA-5tf0A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 8 THR A 229
SER A 528
ARG A 167
GLU A 173
None
1.35A 1xr2B-5tf0A:
undetectable
1xr2B-5tf0A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ILE A 208
LEU A 202
ALA A 144
GLY A 192
SER A 191
None
1.08A 2a58A-5tf0A:
3.9
2a58B-5tf0A:
4.1
2a58A-5tf0A:
12.52
2a58B-5tf0A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ILE A 208
LEU A 202
ALA A 144
GLY A 192
SER A 191
None
1.09A 2a58B-5tf0A:
4.1
2a58C-5tf0A:
4.1
2a58B-5tf0A:
12.52
2a58C-5tf0A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ILE A 208
LEU A 202
ALA A 144
GLY A 192
SER A 191
None
1.08A 2a58D-5tf0A:
4.2
2a58E-5tf0A:
4.1
2a58D-5tf0A:
12.52
2a58E-5tf0A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 4 GLN A  94
GLU A  99
ILE A  98
PRO A 106
None
1.44A 2fcnA-5tf0A:
undetectable
2fcnA-5tf0A:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ALA A 144
LEU A 202
LYS A 203
ILE A 108
LEU A 362
None
0.80A 2oipE-5tf0A:
undetectable
2oipE-5tf0A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ILE A 152
GLY A  80
GLY A 110
PRO A 106
PHE A 363
None
1.18A 2okcB-5tf0A:
undetectable
2okcB-5tf0A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 ARG A 529
GLN A 538
PRO A 535
None
0.89A 2qhfA-5tf0A:
undetectable
2qhfA-5tf0A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 LEU A 516
LEU A 592
LEU A 541
ILE A 463
VAL A 511
None
1.18A 2uxoB-5tf0A:
undetectable
2uxoB-5tf0A:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ILE A 105
GLY A  49
GLY A  76
ALA A  97
PHE A 328
None
1.14A 2yvlB-5tf0A:
undetectable
2yvlB-5tf0A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 PRO A 709
PHE A 650
LYS A 711
None
1.21A 3bjwG-5tf0A:
undetectable
3bjwG-5tf0A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 4 SER A 163
GLY A 219
GLY A 176
GLY A 174
None
0.88A 3bogB-5tf0A:
undetectable
3bogD-5tf0A:
undetectable
3bogB-5tf0A:
undetectable
3bogD-5tf0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.00A 3eeyA-5tf0A:
undetectable
3eeyA-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.00A 3eeyB-5tf0A:
undetectable
3eeyB-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.00A 3eeyC-5tf0A:
3.2
3eeyC-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.01A 3eeyD-5tf0A:
undetectable
3eeyD-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.02A 3eeyE-5tf0A:
undetectable
3eeyE-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.03A 3eeyF-5tf0A:
2.5
3eeyF-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.03A 3eeyH-5tf0A:
undetectable
3eeyH-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.01A 3eeyI-5tf0A:
undetectable
3eeyI-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 169
ASP A 165
ILE A 123
GLY A 126
THR A 558
None
1.03A 3eeyJ-5tf0A:
undetectable
3eeyJ-5tf0A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ALA A 144
LEU A 202
LYS A 203
ILE A 108
LEU A 362
None
0.92A 3hj3B-5tf0A:
undetectable
3hj3B-5tf0A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 ASP A 322
ASN A  52
SER A 297
None
0.75A 3lslA-5tf0A:
undetectable
3lslD-5tf0A:
undetectable
3lslA-5tf0A:
17.03
3lslD-5tf0A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 SER A 297
ASP A 322
ASN A  52
None
0.84A 3lslA-5tf0A:
undetectable
3lslD-5tf0A:
undetectable
3lslA-5tf0A:
17.03
3lslD-5tf0A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 PRO A 572
SER A 404
ASN A 401
None
0.82A 3lslG-5tf0A:
undetectable
3lslG-5tf0A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 452
VAL A 461
GLY A 589
ILE A 588
ILE A 463
None
0.87A 3nuoB-5tf0A:
undetectable
3nuoB-5tf0A:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 GLN A 612
THR A 563
ASN A 609
None
0.85A 3v4tE-5tf0A:
undetectable
3v4tE-5tf0A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 5 LEU A 592
ALA A 587
THR A 555
PHE A 396
None
1.03A 3vasB-5tf0A:
undetectable
3vasB-5tf0A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 5 ARG A 529
VAL A 171
LEU A 125
SER A 172
None
1.38A 4e1gA-5tf0A:
undetectable
4e1gA-5tf0A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 GLY A 221
ASN A 261
ALA A 268
VAL A 230
MET A 232
None
1.37A 4j4vA-5tf0A:
undetectable
4j4vA-5tf0A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_B_SVRB301_1
(NUCLEOCAPSID PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 10 GLY A 221
ASN A 261
ALA A 268
VAL A 230
MET A 232
None
1.38A 4j4vB-5tf0A:
0.0
4j4vB-5tf0A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 GLY A 221
ASN A 261
ALA A 268
VAL A 230
MET A 232
None
1.37A 4j4vD-5tf0A:
undetectable
4j4vE-5tf0A:
undetectable
4j4vD-5tf0A:
15.58
4j4vE-5tf0A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_E_SVRE301_1
(NUCLEOCAPSID PROTEIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 10 GLY A 221
ASN A 261
ALA A 268
VAL A 230
MET A 232
None
1.42A 4j4vA-5tf0A:
0.0
4j4vE-5tf0A:
undetectable
4j4vA-5tf0A:
15.58
4j4vE-5tf0A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 8 HIS A 115
PRO A 124
ALA A 143
TYR A 193
None
0.99A 4k0bB-5tf0A:
undetectable
4k0bB-5tf0A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 169
GLY A 176
LEU A 125
SER A 163
GLY A 174
None
1.22A 4kqiA-5tf0A:
undetectable
4kqiA-5tf0A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ALA A 144
LEU A 202
LYS A 203
ILE A 108
LEU A 362
None
1.02A 4ky8B-5tf0A:
undetectable
4ky8B-5tf0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ALA A 144
LEU A 202
LYS A 203
ILE A 108
LEU A 362
None
1.00A 4ky8C-5tf0A:
undetectable
4ky8C-5tf0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ALA A 144
LEU A 202
LYS A 203
ILE A 108
LEU A 362
None
1.00A 4ky8D-5tf0A:
undetectable
4ky8D-5tf0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 8 HIS A 115
PRO A 124
ALA A 143
TYR A 193
None
0.95A 4l7iB-5tf0A:
undetectable
4l7iB-5tf0A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 LEU A 499
GLY A 468
LEU A 516
ILE A 512
VAL A 552
None
1.13A 4ok1A-5tf0A:
undetectable
4ok1A-5tf0A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 8 LEU A  77
ASN A  52
MET A 343
ILE A 296
None
0.97A 4ok1A-5tf0A:
undetectable
4ok1A-5tf0A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.03A 4qvlK-5tf0A:
undetectable
4qvlL-5tf0A:
undetectable
4qvlK-5tf0A:
13.67
4qvlL-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.03A 4qvlY-5tf0A:
undetectable
4qvlZ-5tf0A:
undetectable
4qvlY-5tf0A:
13.67
4qvlZ-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.03A 4qvmK-5tf0A:
undetectable
4qvmL-5tf0A:
undetectable
4qvmK-5tf0A:
13.98
4qvmL-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 10 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.03A 4qvmY-5tf0A:
undetectable
4qvmZ-5tf0A:
undetectable
4qvmY-5tf0A:
13.98
4qvmZ-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.03A 4qw1K-5tf0A:
undetectable
4qw1L-5tf0A:
undetectable
4qw1K-5tf0A:
13.67
4qw1L-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 10 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.03A 4qw1Y-5tf0A:
undetectable
4qw1Z-5tf0A:
undetectable
4qw1Y-5tf0A:
13.67
4qw1Z-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 10 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.02A 4qw3K-5tf0A:
undetectable
4qw3L-5tf0A:
undetectable
4qw3K-5tf0A:
13.84
4qw3L-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 10 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.02A 4qw3Y-5tf0A:
undetectable
4qw3Z-5tf0A:
undetectable
4qw3Y-5tf0A:
13.84
4qw3Z-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 452
VAL A 461
GLY A 589
ILE A 588
ILE A 463
None
0.88A 4rvjB-5tf0A:
undetectable
4rvjB-5tf0A:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 GLY A 452
VAL A 461
GLY A 589
ILE A 588
ILE A 463
None
0.88A 4rvjD-5tf0A:
undetectable
4rvjD-5tf0A:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 MET A 680
GLN A 696
TYR A 698
None
1.00A 4udcA-5tf0A:
undetectable
4udcA-5tf0A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 7 VAL A 577
ILE A 513
ALA A 427
ILE A 512
None
0.75A 4uxqA-5tf0A:
undetectable
4uxqA-5tf0A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 ASN A 508
THR A 419
ALA A 421
ALA A 466
ILE A 512
None
1.14A 4x1kD-5tf0A:
undetectable
4x1kD-5tf0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 ASN A 239
ILE A 706
SER A 705
GLY A 704
GLU A 750
None
None
None
MG  A 800 ( 4.1A)
None
1.42A 4xt7A-5tf0A:
undetectable
4xt7A-5tf0A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 VAL A 537
LEU A 545
GLY A 424
SER A 469
LEU A 499
None
1.35A 4zbqA-5tf0A:
undetectable
4zbqA-5tf0A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 435
ILE A  90
GLY A 110
HIS A 115
THR A 436
None
1.10A 4zdyA-5tf0A:
undetectable
4zdyA-5tf0A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 7 ASP A 226
ARG A 170
GLY A 524
GLU A 173
None
0.84A 5btaA-5tf0A:
undetectable
5btaC-5tf0A:
undetectable
5btaD-5tf0A:
undetectable
5btaA-5tf0A:
22.51
5btaC-5tf0A:
22.51
5btaD-5tf0A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 7 ASP A 226
ARG A 170
GLY A 524
GLU A 173
None
0.89A 5btfA-5tf0A:
undetectable
5btfB-5tf0A:
2.9
5btfC-5tf0A:
undetectable
5btfA-5tf0A:
22.51
5btfB-5tf0A:
16.92
5btfC-5tf0A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.02A 5bxnK-5tf0A:
undetectable
5bxnL-5tf0A:
undetectable
5bxnK-5tf0A:
13.67
5bxnL-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 11 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.03A 5bxnY-5tf0A:
undetectable
5bxnZ-5tf0A:
undetectable
5bxnY-5tf0A:
13.67
5bxnZ-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.01A 5d0xK-5tf0A:
undetectable
5d0xL-5tf0A:
undetectable
5d0xK-5tf0A:
13.80
5d0xL-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 9 ALA A 421
ALA A 509
GLY A 424
GLY A 468
ALA A 466
None
1.02A 5d0xY-5tf0A:
undetectable
5d0xZ-5tf0A:
undetectable
5d0xY-5tf0A:
13.80
5d0xZ-5tf0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 435
ILE A  90
GLY A 110
HIS A 115
THR A 436
None
1.13A 5eslA-5tf0A:
undetectable
5eslA-5tf0A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 ARG A 708
ASN A 239
ASP A 178
None
0.87A 5gwxA-5tf0A:
undetectable
5gwxA-5tf0A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 LEU A 534
LEU A 564
THR A 565
PRO A 166
ARG A 167
None
1.38A 5hnxB-5tf0A:
1.5
5hnxB-5tf0A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 5 SER A 191
VAL A 190
GLY A 252
ALA A 251
None
0.75A 5k50A-5tf0A:
undetectable
5k50A-5tf0A:
17.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
10 / 12 LEU A  82
ASP A 112
PHE A 156
ARG A 170
LYS A 213
HIS A 214
MET A 257
MET A 323
TRP A 437
GLU A 525
None
EDO  A 802 (-2.9A)
EDO  A 802 (-4.0A)
None
EDO  A 802 ( 3.8A)
None
EDO  A 802 (-3.5A)
EDO  A 802 (-3.6A)
None
None
0.45A 5m6gA-5tf0A:
38.4
5m6gA-5tf0A:
32.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 7 VAL A 397
VAL A 694
GLY A 651
TYR A 652
None
1.00A 5x80C-5tf0A:
undetectable
5x80D-5tf0A:
undetectable
5x80C-5tf0A:
15.48
5x80D-5tf0A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
3 / 3 TYR A 648
ASN A 576
LEU A 399
None
0.80A 6b58A-5tf0A:
undetectable
6b58A-5tf0A:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
5 / 12 GLY A 435
ILE A  90
GLY A 110
HIS A 115
THR A 436
None
1.13A 6e8qA-5tf0A:
undetectable
6e8qA-5tf0A:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis)
4 / 4 LEU A 532
ASP A 165
PRO A 166
ARG A 167
None
0.93A 6fgdA-5tf0A:
3.2
6fgdA-5tf0A:
21.16