SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tfl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)
5tfl CADHERIN-23
(Mus
musculus)
5 / 12 ALA A 779
ILE A 810
SER A 836
VAL A 835
ILE A 833
None
0.98A 4ax8A-5tflA:
undetectable
4ax8A-5tflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)
5tfl CADHERIN-23
(Mus
musculus)
4 / 6 TYR A 760
VAL A 855
VAL A 774
THR A 775
None
1.37A 6f32B-5tflA:
undetectable
6f32B-5tflA:
undetectable