SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tfq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
LYS A  51
SER A 112
ASN A 114
LYS A 215
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
 0.20A 1ghmA-5tfqA:
30.6		 1ghmA-5tfqA:
27.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		8 / 12 SER A  48
LYS A  51
SER A 112
ASN A 114
GLU A 148
THR A 197
LYS A 215
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
 0.30A 1i2wA-5tfqA:
31.5		 1i2wA-5tfqA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
LYS A  51
SER A 112
ASN A 114
GLU A 148
THR A 197
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.3A)
 0.28A 1i2wB-5tfqA:
31.8		 1i2wB-5tfqA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 GLY A 234
ALA A 233
ASP A 232
ILE A 109
VAL A 167
 None
 0.91A 1k6cB-5tfqA:
undetectable		 1k6cB-5tfqA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		8 / 12 SER A  48
LYS A  51
SER A 112
ASN A 114
GLU A 148
THR A 197
LYS A 215
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
 0.53A 1ymxA-5tfqA:
33.2		 1ymxA-5tfqA:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
LYS A  51
SER A 112
LYS A 215
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
None
 0.75A 1ymxA-5tfqA:
33.2		 1ymxA-5tfqA:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		8 / 12 SER A  48
LYS A  51
SER A 112
ASN A 114
GLU A 148
LYS A 215
GLY A 217
SER A 218
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.45A 1ymxB-5tfqA:
33.2		 1ymxB-5tfqA:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		8 / 12 SER A  48
LYS A  51
SER A 112
GLU A 148
LYS A 215
GLY A 217
SER A 218
ASP A 220
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
None
 0.90A 1ymxB-5tfqA:
33.2		 1ymxB-5tfqA:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 GLY A 234
ALA A 233
ASP A 232
ILE A 109
VAL A 167
 None
 0.81A 2b7zB-5tfqA:
undetectable		 2b7zB-5tfqA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 9 LEU A 179
PHE A 180
LEU A 137
LEU A 170
ALA A  57
 None
 1.35A 2bxeA-5tfqA:
undetectable		 2bxeA-5tfqA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 PHE A 187
LEU A 137
GLY A  55
ILE A 191
PHE A 235
 GOL  A 303 ( 4.7A)
None
None
None
None
 1.20A 2zznB-5tfqA:
undetectable		 2zznB-5tfqA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		8 / 12 LYS A  51
TYR A  85
SER A 112
ASN A 114
THR A 197
LYS A 215
GLY A 217
SER A 218
 None
None
PO4  A 301 (-2.6A)
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.46A 3hlwA-5tfqA:
33.3		 3hlwA-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		8 / 12 TYR A  85
SER A 112
ASN A 114
THR A 197
LYS A 215
THR A 216
GLY A 217
SER A 218
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.46A 3hlwB-5tfqA:
33.2		 3hlwB-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 LYS A  51
ASN A 114
LYS A 215
THR A 216
GLY A 217
SER A 218
 None
None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.38A 3huoA-5tfqA:
33.2		 3huoA-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 LYS A  51
LYS A 215
THR A 216
GLY A 217
SER A 218
ASP A 220
 None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
None
 0.89A 3huoA-5tfqA:
33.2		 3huoA-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 LYS A  51
ASN A 114
LYS A 215
GLY A 217
SER A 218
 None
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.36A 3huoB-5tfqA:
33.0		 3huoB-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 LYS A  51
LYS A 215
GLY A 217
SER A 218
ASP A 220
 None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
None
 0.89A 3huoB-5tfqA:
33.0		 3huoB-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.65A 3ny4A-5tfqA:
30.7		 3ny4A-5tfqA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 LYS A  51
SER A 112
ASN A 114
LYS A 215
GLY A 217
SER A 218
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.54A 3q07A-5tfqA:
33.0		 3q07A-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 LYS A  51
SER A 112
ASN A 114
LYS A 215
GLY A 217
SER A 218
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.39A 3q07B-5tfqA:
32.9		 3q07B-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
TYR A  85
SER A 112
ASN A 114
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.27A 3sh8A-5tfqA:
31.2		 3sh8A-5tfqA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
LYS A  51
SER A 112
ASN A 114
LYS A 215
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
 0.29A 3sh8B-5tfqA:
31.1		 3sh8B-5tfqA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		4 / 6 LYS A   6
ILE A   9
VAL A 271
LEU A 275
 None
 0.87A 4em2A-5tfqA:
undetectable		 4em2A-5tfqA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 LYS A  51
SER A 112
ASN A 114
THR A 197
LYS A 215
THR A 216
GLY A 217
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.37A 4euzA-5tfqA:
32.5		 4euzA-5tfqA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 10 TYR A  85
SER A 112
ASN A 114
LYS A 215
THR A 216
GLY A 217
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.49A 4fh2A-5tfqA:
31.3		 4fh2A-5tfqA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
TYR A  85
SER A 112
ASN A 114
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.28A 4n9kA-5tfqA:
31.7		 4n9kA-5tfqA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
SER A 112
ASN A 114
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.25A 4n9kB-5tfqA:
31.6		 4n9kB-5tfqA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 LEU A  17
ASN A 260
ILE A 263
ILE A 264
VAL A 248
 None
 1.12A 4nkvC-5tfqA:
undetectable		 4nkvC-5tfqA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		8 / 12 TYR A  85
SER A 112
ASN A 114
THR A 197
LYS A 215
THR A 216
GLY A 217
SER A 218
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.61A 4pm5A-5tfqA:
33.0		 4pm5A-5tfqA:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 LYS A  51
TYR A  85
SER A 112
ASN A 114
THR A 197
LYS A 215
GLY A 217
 None
None
PO4  A 301 (-2.6A)
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
 0.62A 4pm7A-5tfqA:
33.0		 4pm7A-5tfqA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 TYR A  85
SER A 112
ASN A 114
THR A 197
LYS A 215
THR A 216
GLY A 217
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.60A 4pm9A-5tfqA:
33.0		 4pm9A-5tfqA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		4 / 7 PHE A  52
ALA A 174
LEU A  59
PHE A 180
 None
 0.89A 4uymA-5tfqA:
undetectable		 4uymA-5tfqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		4 / 7 PHE A  52
ALA A 174
LEU A  59
PHE A 180
 None
 0.81A 4uymB-5tfqA:
undetectable		 4uymB-5tfqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		3 / 3 THR A 256
ASP A 257
ALA A 258
 None
 0.10A 5g5gB-5tfqA:
undetectable		 5g5gB-5tfqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 SER A  48
SER A 112
ASN A 114
LYS A 215
GLY A 217
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
 0.30A 5ghyA-5tfqA:
31.6		 5ghyA-5tfqA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 SER A  48
SER A 112
ASN A 114
LYS A 215
GLY A 217
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
 0.28A 5ghyB-5tfqA:
31.6		 5ghyB-5tfqA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 11 SER A  48
TYR A  85
SER A 112
ASN A 114
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.29A 5ghzA-5tfqA:
31.7		 5ghzA-5tfqA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 10 SER A  48
TYR A  85
SER A 112
ASN A 114
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.27A 5ghzB-5tfqA:
31.7		 5ghzB-5tfqA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		4 / 9 LYS A   8
ILE A   9
ILE A  13
LEU A  16
 None
 0.55A 5vkqB-5tfqA:
undetectable
5vkqC-5tfqA:
undetectable		 5vkqB-5tfqA:
9.83
5vkqC-5tfqA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		3 / 3 TYR A 245
ASP A  32
ASP A 175
 None
 0.72A 5x6yA-5tfqA:
undetectable		 5x6yA-5tfqA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.63A 6b5yB-5tfqA:
31.2		 6b5yB-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.64A 6b5yD-5tfqA:
31.2		 6b5yD-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.53A 6b68B-5tfqA:
31.4		 6b68B-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
None
 0.56A 6b68D-5tfqA:
31.3		 6b68D-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.54A 6b69A-5tfqA:
31.1
6b69B-5tfqA:
31.3		 6b69A-5tfqA:
11.76
6b69B-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.22A 6b69D-5tfqA:
31.3		 6b69D-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.53A 6b6aB-5tfqA:
31.2		 6b6aB-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
SER A 112
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.45A 6b6aD-5tfqA:
31.2		 6b6aD-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		5 / 12 SER A  48
SER A 112
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.38A 6b6cA-5tfqA:
31.2		 6b6cA-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.55A 6b6dA-5tfqA:
31.0		 6b6dA-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
SER A 112
THR A 197
LYS A 215
THR A 216
GLY A 217
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
 0.32A 6b6eA-5tfqA:
31.1		 6b6eA-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		6 / 12 SER A  48
SER A 112
LYS A 215
THR A 216
GLY A 217
ASP A 220
 PO4  A 301 (-3.8A)
PO4  A 301 (-2.6A)
PO4  A 301 (-3.2A)
PO4  A 301 ( 3.6A)
PO4  A 301 (-3.3A)
None
 0.75A 6b6fA-5tfqA:
30.9		 6b6fA-5tfqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 5tfq BETA-LACTAMASE
(Bacteroides
cellulosilyticus) 		7 / 12 TYR A  85
SER A 112
ASN A 114
THR A 197
LYS A 215
GLY A 217
SER A 218
 None
PO4  A 301 (-2.6A)
None
PO4  A 301 ( 3.8A)
PO4  A 301 (-3.2A)
PO4  A 301 (-3.3A)
PO4  A 301 (-2.7A)
 0.34A 6c79A-5tfqA:
33.0		 6c79A-5tfqA:
15.36