SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		4 / 7 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.87A 1th6A-5tfvA:
20.9		 1th6A-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		4 / 7 HIS A  48
TYR A  52
PRO A  68
LYS A  69
 None
 0.65A 1th6A-5tfvA:
20.9		 1th6A-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 11 LEU A   2
GLY A  32
HIS A  48
TYR A  52
LYS A  69
 None
 1.09A 1y4lB-5tfvA:
20.7		 1y4lB-5tfvA:
59.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 11 LEU A   2
GLY A  33
HIS A  48
TYR A  52
LYS A  69
 None
 1.00A 1y4lB-5tfvA:
20.7		 1y4lB-5tfvA:
59.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		4 / 7 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.88A 2armA-5tfvA:
20.8		 2armA-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		4 / 7 HIS A  48
TYR A  52
PRO A  68
LYS A  69
 None
 0.63A 2armA-5tfvA:
20.8		 2armA-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 10 LEU A   2
HIS A  48
ASP A  49
LYS A  69
PHE A 106
 None
 0.99A 2b17A-5tfvA:
21.0		 2b17A-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
 0.83A 2dpzA-5tfvA:
21.0		 2dpzA-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		3 / 3 ASP A  49
TYR A  52
LYS A  69
 None
 0.82A 2othA-5tfvA:
21.0		 2othA-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 10 GLU A   4
LYS A   7
PRO A  18
THR A  23
ARG A  72
 None
 1.10A 3bjwD-5tfvA:
20.9		 3bjwD-5tfvA:
59.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 10 GLU A   4
LYS A   7
PRO A  18
THR A  23
LYS A  69
 None
 0.66A 3bjwD-5tfvA:
20.9		 3bjwD-5tfvA:
59.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 12 PRO A  18
PHE A  19
PRO A  20
THR A  23
LYS A 115
 None
None
None
None
TRS  A 201 (-3.3A)
 0.71A 3bjwF-5tfvA:
20.8		 3bjwF-5tfvA:
59.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
LYS A  69
 None
 0.89A 3fo7A-5tfvA:
20.9		 3fo7A-5tfvA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.76A 3h1xA-5tfvA:
20.9		 3h1xA-5tfvA:
68.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 12 GLY A  85
GLY A  87
ARG A  77
SER A  74
GLU A  12
 None
 1.40A 3tkaA-5tfvA:
undetectable		 3tkaA-5tfvA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III
(Bothrops
asper) 		5 / 9 VAL A  47
ALA A 102
PHE A 106
TYR A 113
TYR A  25
 None
 1.38A 4lb2B-5tfvA:
undetectable		 4lb2B-5tfvA:
12.27