SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tfy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 5tfy FLAGELLIN
(Methanospirillum
hungatei) 		5 / 12 THR I 121
LEU I 102
TRP I  92
LEU I 138
PRO I 125
 None
 1.27A 4xi3D-5tfyI:
undetectable		 4xi3D-5tfyI:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5tfy FLAGELLIN
(Methanospirillum
hungatei) 		4 / 6 ILE I 122
ILE I 131
LEU I 154
PHE I 136
 None
 1.04A 5vkqA-5tfyI:
undetectable
5vkqB-5tfyI:
undetectable		 5vkqA-5tfyI:
6.85
5vkqB-5tfyI:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5tfy FLAGELLIN
(Methanospirillum
hungatei) 		4 / 6 ILE I 122
ILE I 131
LEU I 154
PHE I 136
 None
 1.02A 5vkqA-5tfyI:
undetectable
5vkqD-5tfyI:
undetectable		 5vkqA-5tfyI:
6.85
5vkqD-5tfyI:
6.85