SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tfz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 TRP A 110
PHE A 117
TRP A  26
 7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
7BC  A 202 (-3.6A)
 1.25A 1r15C-5tfzA:
undetectable		 1r15C-5tfzA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 TRP A 110
PHE A 117
TRP A  26
 7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
7BC  A 202 (-3.6A)
 1.26A 1r15F-5tfzA:
undetectable		 1r15F-5tfzA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 TRP A 110
PHE A 117
TRP A  26
 7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
7BC  A 202 (-3.6A)
 1.26A 1r15G-5tfzA:
undetectable		 1r15G-5tfzA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 TRP A 110
PHE A 117
TRP A  26
 7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
7BC  A 202 (-3.6A)
 1.26A 1r15H-5tfzA:
undetectable		 1r15H-5tfzA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.74A 1v54A-5tfzA:
undetectable		 1v54A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 1v54N-5tfzA:
undetectable		 1v54N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 1v55A-5tfzA:
undetectable		 1v55A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 1v55N-5tfzA:
undetectable		 1v55N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 2dyrA-5tfzA:
undetectable		 2dyrA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 2dyrN-5tfzA:
undetectable		 2dyrN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 2dysA-5tfzA:
undetectable		 2dysA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 2dysN-5tfzA:
undetectable		 2dysN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 2eijA-5tfzA:
undetectable		 2eijA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 2eijN-5tfzA:
undetectable		 2eijN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.70A 2eikA-5tfzA:
undetectable		 2eikA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 2eikN-5tfzA:
undetectable		 2eikN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 2eilA-5tfzA:
undetectable		 2eilA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.76A 2eilN-5tfzA:
undetectable		 2eilN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 2eimA-5tfzA:
undetectable		 2eimA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 2eimN-5tfzA:
undetectable		 2eimN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 4 LEU A  55
THR A  54
ILE A  90
HIS A  58
 None
None
None
NI  A 201 ( 3.3A)
 1.35A 2jfaB-5tfzA:
undetectable		 2jfaB-5tfzA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 2y69A-5tfzA:
undetectable		 2y69A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 2y69N-5tfzA:
undetectable		 2y69N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.78A 2zxwA-5tfzA:
undetectable		 2zxwA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.77A 2zxwN-5tfzA:
undetectable		 2zxwN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.69A 3abkA-5tfzA:
undetectable		 3abkA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.68A 3abkN-5tfzA:
undetectable		 3abkN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.79A 3ablN-5tfzA:
undetectable		 3ablN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.74A 3abmA-5tfzA:
undetectable		 3abmA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.77A 3abmN-5tfzA:
undetectable		 3abmN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.68A 3ag1A-5tfzA:
undetectable		 3ag1A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.70A 3ag1N-5tfzA:
undetectable		 3ag1N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 3ag2A-5tfzA:
undetectable		 3ag2A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 3ag2N-5tfzA:
undetectable		 3ag2N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.70A 3ag3A-5tfzA:
undetectable		 3ag3A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.70A 3ag3N-5tfzA:
undetectable		 3ag3N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.66A 3ag4A-5tfzA:
undetectable		 3ag4A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.69A 3ag4N-5tfzA:
undetectable		 3ag4N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 3asnA-5tfzA:
undetectable		 3asnA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.74A 3asnN-5tfzA:
undetectable		 3asnN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 3asoA-5tfzA:
undetectable		 3asoA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.74A 3asoN-5tfzA:
undetectable		 3asoN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.74A 3dtuA-5tfzA:
undetectable		 3dtuA-5tfzA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 3dtuC-5tfzA:
undetectable		 3dtuC-5tfzA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		5 / 12 LEU A  53
TYR A  21
HIS A  56
PHE A 117
PHE A 112
 7BC  A 202 (-4.9A)
None
NI  A 201 ( 3.8A)
7BC  A 202 ( 4.9A)
None
 1.39A 3r43A-5tfzA:
undetectable		 3r43A-5tfzA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		5 / 12 TYR A  21
HIS A  56
TRP A 110
PHE A 117
PHE A 112
 None
NI  A 201 ( 3.8A)
7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
None
 1.24A 3r43A-5tfzA:
undetectable		 3r43A-5tfzA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6I_A_JMSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		6 / 12 LEU A  53
TYR A  21
HIS A  56
TRP A 110
PHE A 117
PHE A 112
 7BC  A 202 (-4.9A)
None
NI  A 201 ( 3.8A)
7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
None
 1.40A 3r6iA-5tfzA:
undetectable		 3r6iA-5tfzA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R7M_A_SUZA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		6 / 10 LEU A  53
TYR A  21
HIS A  56
TRP A 110
PHE A 117
PHE A 112
 7BC  A 202 (-4.9A)
None
NI  A 201 ( 3.8A)
7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
None
 1.39A 3r7mA-5tfzA:
undetectable		 3r7mA-5tfzA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		5 / 12 TYR A  21
HIS A  56
TRP A 110
PHE A 117
PHE A 112
 None
NI  A 201 ( 3.8A)
7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
None
 1.31A 3r94A-5tfzA:
undetectable		 3r94A-5tfzA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 3x2qA-5tfzA:
undetectable		 3x2qA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 3x2qN-5tfzA:
undetectable		 3x2qN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 6 HIS A  58
HIS A  96
TYR A  64
GLU A  62
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
7BC  A 202 (-4.6A)
7BC  A 202 ( 2.4A)
 0.97A 4pahA-5tfzA:
undetectable		 4pahA-5tfzA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		5 / 12 LEU A  53
PHE A 112
HIS A  58
HIS A  96
LEU A  98
 7BC  A 202 (-4.9A)
None
NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
None
 1.38A 4r88A-5tfzA:
undetectable		 4r88A-5tfzA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 HIS A  58
TRP A  26
PHE A  28
THR A  54
 NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
None
 1.28A 4tzuB-5tfzA:
undetectable
4tzuC-5tfzA:
undetectable		 4tzuB-5tfzA:
21.15
4tzuC-5tfzA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_C_Y70C504_1
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 THR A  54
HIS A  58
TRP A  26
PHE A  28
 None
NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
 1.29A 4tzuB-5tfzA:
undetectable
4tzuC-5tfzA:
undetectable		 4tzuB-5tfzA:
21.15
4tzuC-5tfzA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 TYR A 122
ILE A 111
HIS A  56
LEU A  53
 7BC  A 202 (-4.7A)
None
NI  A 201 ( 3.8A)
7BC  A 202 (-4.9A)
 1.22A 4xo7B-5tfzA:
undetectable		 4xo7B-5tfzA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 5b1aA-5tfzA:
undetectable		 5b1aA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.76A 5b1aN-5tfzA:
undetectable		 5b1aN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.70A 5b1bA-5tfzA:
undetectable		 5b1bA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 5b1bN-5tfzA:
undetectable		 5b1bN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 5b3sA-5tfzA:
undetectable		 5b3sA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 5b3sN-5tfzA:
undetectable		 5b3sN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 5iy5A-5tfzA:
undetectable		 5iy5A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 5iy5N-5tfzA:
undetectable		 5iy5N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 4 HIS A  58
HIS A  96
TYR A  64
GLU A  62
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
7BC  A 202 (-4.6A)
7BC  A 202 ( 2.4A)
 0.98A 5pahA-5tfzA:
undetectable		 5pahA-5tfzA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 5w97a-5tfzA:
undetectable		 5w97a-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.71A 5waua-5tfzA:
undetectable		 5waua-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.67A 5x19A-5tfzA:
undetectable		 5x19A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.68A 5x19N-5tfzA:
undetectable		 5x19N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.70A 5x1bA-5tfzA:
undetectable		 5x1bA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.67A 5x1bN-5tfzA:
undetectable		 5x1bN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.67A 5x1fA-5tfzA:
undetectable		 5x1fA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.67A 5x1fN-5tfzA:
undetectable		 5x1fN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 5xdqA-5tfzA:
undetectable		 5xdqA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 5xdqN-5tfzA:
undetectable		 5xdqN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 5xdxA-5tfzA:
undetectable		 5xdxA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 5xdxN-5tfzA:
undetectable		 5xdxN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_G_EF2G501_1
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 HIS A  58
TRP A  26
PHE A  28
THR A  54
 NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
None
 1.28A 5yizG-5tfzA:
undetectable
5yizY-5tfzA:
undetectable		 5yizG-5tfzA:
20.67
5yizY-5tfzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_T_EF2T501_1
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 THR A  54
HIS A  58
TRP A  26
PHE A  28
 None
NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
 1.30A 5yizk-5tfzA:
undetectable
5yizt-5tfzA:
undetectable		 5yizk-5tfzA:
20.67
5yizt-5tfzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_G_EF2G501_1
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 HIS A  58
TRP A  26
PHE A  28
THR A  54
 NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
None
 1.31A 5yj0G-5tfzA:
undetectable
5yj0Y-5tfzA:
undetectable		 5yj0G-5tfzA:
20.67
5yj0Y-5tfzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_K_EF2K501_1
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 HIS A  58
TRP A  26
PHE A  28
THR A  54
 NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
None
 1.31A 5yj0k-5tfzA:
undetectable
5yj0t-5tfzA:
undetectable		 5yj0k-5tfzA:
20.67
5yj0t-5tfzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_T_EF2T501_1
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 THR A  54
HIS A  58
TRP A  26
PHE A  28
 None
NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
 1.32A 5yj0k-5tfzA:
undetectable
5yj0t-5tfzA:
undetectable		 5yj0k-5tfzA:
20.67
5yj0t-5tfzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 8 HIS A  58
TRP A  26
PHE A  28
THR A  54
 NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
None
 1.26A 5yj1G-5tfzA:
undetectable
5yj1Y-5tfzA:
undetectable		 5yj1G-5tfzA:
20.51
5yj1Y-5tfzA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_K_6ELK501_0
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 HIS A  58
TRP A  26
PHE A  28
THR A  54
 NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
None
 1.33A 5yj1k-5tfzA:
undetectable
5yj1t-5tfzA:
undetectable		 5yj1k-5tfzA:
20.51
5yj1t-5tfzA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 8 THR A  54
HIS A  58
TRP A  26
PHE A  28
 None
NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
 1.28A 5yj1k-5tfzA:
undetectable
5yj1t-5tfzA:
undetectable		 5yj1k-5tfzA:
20.51
5yj1t-5tfzA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 7 THR A  54
HIS A  58
TRP A  26
PHE A  28
 None
NI  A 201 ( 3.3A)
7BC  A 202 (-3.6A)
None
 1.29A 5yj1G-5tfzA:
undetectable
5yj1Y-5tfzA:
undetectable		 5yj1G-5tfzA:
20.51
5yj1Y-5tfzA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.76A 5z84A-5tfzA:
undetectable		 5z84A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.77A 5z85A-5tfzA:
undetectable		 5z85A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 5z86A-5tfzA:
undetectable		 5z86A-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.78A 5z86N-5tfzA:
undetectable		 5z86N-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 5zcoA-5tfzA:
undetectable		 5zcoA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.74A 5zcpA-5tfzA:
undetectable		 5zcpA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.79A 5zcpN-5tfzA:
undetectable		 5zcpN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.75A 5zcqA-5tfzA:
undetectable		 5zcqA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.77A 5zcqN-5tfzA:
undetectable		 5zcqN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 6giqa-5tfzA:
undetectable		 6giqa-5tfzA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.76A 6nknA-5tfzA:
undetectable		 6nknA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.76A 6nknN-5tfzA:
undetectable		 6nknN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.69A 6nmfA-5tfzA:
undetectable		 6nmfA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.69A 6nmfN-5tfzA:
undetectable		 6nmfN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.72A 6nmpA-5tfzA:
undetectable		 6nmpA-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		3 / 3 HIS A  58
HIS A  96
HIS A  56
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
NI  A 201 ( 3.8A)
 0.73A 6nmpN-5tfzA:
undetectable		 6nmpN-5tfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK
(Candidatus
Pelagibacter
ubique) 		4 / 6 HIS A  58
HIS A  96
TYR A  64
GLU A  62
 NI  A 201 ( 3.3A)
NI  A 201 ( 3.5A)
7BC  A 202 (-4.6A)
7BC  A 202 ( 2.4A)
 0.96A 6pahA-5tfzA:
undetectable		 6pahA-5tfzA:
18.33