SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tg8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.07A 1jhoA-5tg8A:
undetectable		 1jhoA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.02A 1jhrA-5tg8A:
undetectable		 1jhrA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.04A 1jhyA-5tg8A:
undetectable		 1jhyA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.03A 1l4nA-5tg8A:
undetectable		 1l4nA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.06A 1l5kA-5tg8A:
undetectable		 1l5kA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.04A 1l5lA-5tg8A:
undetectable		 1l5lA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.04A 1l5mA-5tg8A:
undetectable		 1l5mA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ARG A  91
ASP A 298
ASN A 296
 None
 0.64A 1nbhA-5tg8A:
undetectable		 1nbhA-5tg8A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ARG A  91
ASP A 298
ASN A 296
 None
 0.62A 1nbhD-5tg8A:
undetectable		 1nbhD-5tg8A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ALA A 257
VAL A 179
TRP A 234
 None
 0.83A 1tkqB-5tg8A:
undetectable		 1tkqB-5tg8A:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 VAL A 243
THR A 244
PHE A 245
THR A 246
 None
 1.10A 2kotA-5tg8A:
undetectable		 2kotA-5tg8A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 PHE A  82
SER A 265
SER A 115
 None
 0.94A 3ufgB-5tg8A:
undetectable		 3ufgB-5tg8A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 6 THR A 287
GLY A  47
ARG A 300
ILE A 297
 None
 1.07A 4acbC-5tg8A:
undetectable		 4acbC-5tg8A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.91A 4eq4A-5tg8A:
undetectable		 4eq4A-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.92A 4eqlA-5tg8A:
undetectable		 4eqlA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.93A 4eqlB-5tg8A:
undetectable		 4eqlB-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 GLU A 261
TYR A 261
GLY A 116
ARG A 261
 None
 1.02A 4fgzA-5tg8A:
undetectable		 4fgzA-5tg8A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 8 GLU A 261
TYR A 261
GLY A 116
ARG A 261
 None
 0.99A 4fgzA-5tg8A:
undetectable
4fgzB-5tg8A:
undetectable		 4fgzA-5tg8A:
21.94
4fgzB-5tg8A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ASP A 298
ARG A 300
ASP A 271
 None
 0.89A 4fzvA-5tg8A:
undetectable		 4fzvA-5tg8A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 9 GLY A 116
LEU A 260
SER A 265
GLU A 114
ARG A 113
 None
 1.04A 4kqiA-5tg8A:
undetectable		 4kqiA-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 6 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.94A 4l39A-5tg8A:
undetectable		 4l39A-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.93A 4l39B-5tg8A:
undetectable		 4l39B-5tg8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 12 GLY A 134
ALA A 135
SER A 146
ILE A 130
GLN A 166
 None
 1.15A 4rtpA-5tg8A:
undetectable		 4rtpA-5tg8A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 12 GLY A 205
TYR A 127
PHE A 161
PHE A 125
THR A 203
 None
 1.07A 5eskA-5tg8A:
undetectable		 5eskA-5tg8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 12 PRO A 215
ALA A 250
THR A 136
PHE A 147
ILE A 252
 None
 1.34A 5hgcA-5tg8A:
undetectable		 5hgcA-5tg8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 12 PHE A 102
ILE A  66
GLN A 110
LEU A 260
ILE A  70
 None
 1.22A 5y2tB-5tg8A:
undetectable		 5y2tB-5tg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ASP A 298
ARG A 300
ASP A 271
 None
 0.65A 5zvgA-5tg8A:
undetectable		 5zvgA-5tg8A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ASP A 298
ARG A 300
ASP A 271
 None
 0.71A 5zvgB-5tg8A:
undetectable		 5zvgB-5tg8A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5tg8 HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 12 GLY A 205
TYR A 127
PHE A 161
PHE A 125
THR A 203
 None
 1.02A 6e8qA-5tg8A:
undetectable		 6e8qA-5tg8A:
12.35