SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 5tge PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		3 / 3 GLU A 404
HIS A 427
ASP A 294
 None
 0.76A 1i9gA-5tgeA:
undetectable		 1i9gA-5tgeA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 5tge PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 4 SER A 382
ILE A 381
VAL A 371
THR A 367
 None
 1.07A 1u70A-5tgeA:
undetectable		 1u70A-5tgeA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5tge PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		3 / 3 TYR A 301
HIS A 427
ARG A 319
 None
 1.20A 4e7bC-5tgeA:
undetectable		 4e7bC-5tgeA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5tge PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		3 / 3 GLU A 404
HIS A 427
ASP A 294
 None
 0.87A 5c0oG-5tgeA:
undetectable		 5c0oG-5tgeA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5tge PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 6 ASP A 310
ASP A 445
ASN A 383
GLN A 440
 None
 1.15A 5l6eA-5tgeA:
undetectable		 5l6eA-5tgeA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 5tge PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 8 TYR A 271
ASP A 398
THR A 400
VAL A 303
 None
 1.25A 5ov9B-5tgeA:
undetectable		 5ov9B-5tgeA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5tge PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		3 / 3 ARG A 425
HIS A 427
ARG A 319
 None
 1.19A 6dwdD-5tgeA:
undetectable		 6dwdD-5tgeA:
17.63