SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tgf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		4 / 6 PHE A 167
LYS A  61
ALA A  64
MET A 152
 None
GOL  A 401 ( 4.3A)
None
None
 1.20A 1hk2A-5tgfA:
undetectable		 1hk2A-5tgfA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 GLY A  69
ALA A  70
ASP A  73
GLY A 221
ILE A 217
 None
 0.85A 1k6cB-5tgfA:
undetectable		 1k6cB-5tgfA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 GLY A 156
THR A  75
VAL A  72
LEU A 104
LEU A 103
 None
 1.05A 1mx1C-5tgfA:
undetectable		 1mx1C-5tgfA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		4 / 7 PHE A  10
VAL A 302
GLY A 301
ILE A 336
 None
 0.58A 1p2yA-5tgfA:
undetectable		 1p2yA-5tgfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 9 LEU A 329
TYR A  26
TRP A  20
GLY A  29
ALA A  30
 None
 1.28A 1pxxB-5tgfA:
undetectable		 1pxxB-5tgfA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		3 / 3 SER A 184
VAL A  56
LEU A 203
 None
 0.70A 1yajG-5tgfA:
undetectable		 1yajG-5tgfA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 LEU A 104
ILE A 154
ALA A 155
ALA A 159
THR A  75
 None
 1.08A 2fr3A-5tgfA:
undetectable		 2fr3A-5tgfA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 10 GLY A  69
ALA A  70
ASP A  73
GLY A 221
ILE A 217
 None
 0.94A 2r5qD-5tgfA:
undetectable		 2r5qD-5tgfA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 10 GLY A  69
ALA A  70
ASP A  73
GLY A 221
ILE A 217
 None
 0.87A 3ekvA-5tgfA:
undetectable		 3ekvA-5tgfA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		6 / 11 LEU A 329
TYR A  26
TRP A  20
ILE A  31
GLY A  29
ALA A  30
 None
 1.48A 3n8yA-5tgfA:
undetectable		 3n8yA-5tgfA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 9 GLY A  69
ALA A  70
ASP A  73
GLY A 221
ILE A 217
 None
 0.80A 3ogpA-5tgfA:
undetectable		 3ogpA-5tgfA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 9 GLY A  69
ALA A  70
ASP A  73
GLY A 221
ILE A 217
 None
 0.85A 3ogpB-5tgfA:
undetectable		 3ogpB-5tgfA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 11 VAL A  56
ALA A  57
GLY A 201
TYR A 147
TYR A 252
 None
GOL  A 401 ( 4.7A)
GOL  A 401 (-3.4A)
GOL  A 402 ( 4.1A)
None
 1.38A 3qxyB-5tgfA:
undetectable
3qxyQ-5tgfA:
undetectable		 3qxyB-5tgfA:
22.50
3qxyQ-5tgfA:
3.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		6 / 12 ILE A 228
LEU A 170
LYS A 165
MET A 163
ALA A  66
PRO A 178
 None
 1.44A 3vrmA-5tgfA:
undetectable		 3vrmA-5tgfA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		4 / 5 LEU A 207
ILE A  17
ALA A 308
PHE A 306
 None
 1.07A 4dc3B-5tgfA:
undetectable		 4dc3B-5tgfA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_2
(SUGAR KINASE PROTEIN)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		4 / 4 SER A 322
TYR A  26
GLY A 288
PRO A 287
 None
 1.28A 4e3aA-5tgfA:
undetectable		 4e3aA-5tgfA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		4 / 8 ASN A  36
ASP A  37
HIS A 219
TYR A 218
 None
 1.07A 4f5zA-5tgfA:
undetectable		 4f5zA-5tgfA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 LEU A 199
GLY A 200
SER A 108
TYR A 113
LEU A 125
 None
GOL  A 401 ( 4.5A)
None
GOL  A 401 (-4.8A)
None
 1.29A 5czyA-5tgfA:
undetectable		 5czyA-5tgfA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 GLY A 201
VAL A 189
TYR A 210
ILE A 307
VAL A  54
 GOL  A 401 (-3.4A)
None
None
None
None
 1.07A 5n0sA-5tgfA:
undetectable		 5n0sA-5tgfA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 GLY A 201
VAL A 189
TYR A 210
ILE A 307
VAL A  54
 GOL  A 401 (-3.4A)
None
None
None
None
 1.09A 5n0wB-5tgfA:
undetectable		 5n0wB-5tgfA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 GLY A 201
VAL A 189
TYR A 210
ILE A 307
VAL A  54
 GOL  A 401 (-3.4A)
None
None
None
None
 1.09A 5n0xA-5tgfA:
undetectable		 5n0xA-5tgfA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 12 GLY A 201
VAL A 189
TYR A 210
ILE A 307
VAL A  54
 GOL  A 401 (-3.4A)
None
None
None
None
 1.08A 5n4iA-5tgfA:
undetectable		 5n4iA-5tgfA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		4 / 5 GLY A 301
ASP A 300
ARG A 299
GLN A 238
 None
 1.10A 5zrfB-5tgfA:
undetectable		 5zrfB-5tgfA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		5 / 9 ALA A  57
SER A  58
GLY A  60
ALA A 196
GLY A 202
 GOL  A 401 ( 4.7A)
GOL  A 401 ( 4.1A)
None
None
None
 1.02A 6bklE-5tgfA:
undetectable
6bklF-5tgfA:
undetectable
6bklG-5tgfA:
undetectable
6bklH-5tgfA:
undetectable		 6bklE-5tgfA:
6.06
6bklF-5tgfA:
6.06
6bklG-5tgfA:
6.06
6bklH-5tgfA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5tgf UNCHARACTERIZED
PROTEIN
(Bacteroides
dorei) 		3 / 3 GLN A 283
TYR A 282
ASN A 297
 None
 1.00A 6dwdC-5tgfA:
undetectable		 6dwdC-5tgfA:
19.24