SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tgn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	5tgn	UNCHARACTERIZED PROTEIN (Sphaerobacter thermophilus)	5 / 12	ARG A 97 ALA A 47 ILE A 46 SER A 20 ALA A 24	None	0.99A	2bxpA-5tgnA: undetectable	2bxpA-5tgnA: 8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGP_A_PCFA1213_1 (WNT INHIBITORY FACTOR 1)	5tgn	UNCHARACTERIZED PROTEIN (Sphaerobacter thermophilus)	5 / 9	ILE A 87 ILE A 103 PHE A 49 ILE A 61 PHE A 91	GOL A 202 ( 4.5A) GOL A 202 ( 4.2A) None None None	1.28A	2ygpA-5tgnA: undetectable	2ygpA-5tgnA: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E00_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	5tgn	UNCHARACTERIZED PROTEIN (Sphaerobacter thermophilus)	5 / 12	ALA A 52 PHE A 49 ALA A 48 VAL A 77 ILE A 87	None None None None GOL A 202 ( 4.5A)	1.08A	3e00A-5tgnA: undetectable	3e00A-5tgnA: 12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B7Q_C_ZMRC601_2 (NEURAMINIDASE)	5tgn	UNCHARACTERIZED PROTEIN (Sphaerobacter thermophilus)	3 / 3	ARG A 100 ARG A 99 ILE A 33	None	0.86A	4b7qC-5tgnA: undetectable	4b7qC-5tgnA: 11.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BXP_A_P1ZA3001_1","SERUM ALBUMIN","5tgn","UNCHARACTERIZED PROTEIN","Sphaerobacter thermophilus",5,"ARG A  97;ALA A  47;ILE A  46;SER A  20;ALA A  24","None","0.99A","2bxpA-5tgnA:undetectable","2bxpA-5tgnA:8.78"],["2YGP_A_PCFA1213_1","WNT INHIBITORY FACTOR 1","5tgn","UNCHARACTERIZED PROTEIN","Sphaerobacter thermophilus",5,"ILE A  87;ILE A 103;PHE A  49;ILE A  61;PHE A  91","GOL A 202 ( 4.5A);GOL A 202 ( 4.2A);None;None;None","1.28A","2ygpA-5tgnA:undetectable","2ygpA-5tgnA:19.79"],["3E00_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","5tgn","UNCHARACTERIZED PROTEIN","Sphaerobacter thermophilus",5,"ALA A  52;PHE A  49;ALA A  48;VAL A  77;ILE A  87","None;None;None;None;GOL A 202 ( 4.5A)","1.08A","3e00A-5tgnA:undetectable","3e00A-5tgnA:12.36"],["4B7Q_C_ZMRC601_2","NEURAMINIDASE","5tgn","UNCHARACTERIZED PROTEIN","Sphaerobacter thermophilus",3,"ARG A 100;ARG A  99;ILE A  33","None","0.86A","4b7qC-5tgnA:undetectable","4b7qC-5tgnA:11.32"]]