SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5the'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 7 SER A1143
ASN A1175
CYH A1174
TYR A1156
 None
 0.96A 1dssG-5theA:
2.4		 1dssG-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 8 SER A1143
ASN A1175
CYH A1174
TYR A1156
 None
 0.95A 1dssR-5theA:
2.0		 1dssR-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 6 GLY A 832
SER A 870
LEU A 905
ILE A 828
 None
 0.84A 1yajF-5theA:
undetectable		 1yajF-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		3 / 3 THR A 869
PRO A 871
PRO A 834
 None
 0.69A 2d55C-5theA:
undetectable		 2d55C-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		3 / 3 PRO A 834
THR A 869
PRO A 871
 None
 0.78A 2d55C-5theA:
undetectable		 2d55C-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		5 / 9 LEU A 880
LEU A 879
ILE A 828
LEU A 905
ILE A 908
 None
 1.21A 2f78B-5theA:
undetectable		 2f78B-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 6 GLY A 832
PHE A 831
PRO A 871
THR A 869
 None
 1.19A 2m2oB-5theA:
undetectable		 2m2oB-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		5 / 12 ILE A 786
LEU A 877
LEU A 905
ILE A 908
LEU A 879
 None
 1.26A 3a50E-5theA:
undetectable		 3a50E-5theA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		5 / 12 GLY A 832
GLY A 872
LEU A 876
CYH A1206
ASN A 788
 None
 1.05A 3av6A-5theA:
undetectable		 3av6A-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 8 SER A1143
ASN A1175
CYH A1174
TYR A1156
 None
 0.95A 3dmtC-5theA:
3.9		 3dmtC-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		5 / 11 VAL A 729
ILE A1131
ILE A1141
VAL A 237
ILE A 239
 None
 0.92A 3ekxB-5theA:
undetectable		 3ekxB-5theA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 7 LEU A1237
ARG A1203
SER A1020
GLY A1002
 None
U  B   1 ( 4.0A)
None
None
 0.92A 3hcrB-5theA:
5.5		 3hcrB-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 7 SER A1020
LEU A1037
ARG A1025
ILE A1064
 None
 1.09A 3ln1C-5theA:
undetectable		 3ln1C-5theA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		3 / 3 GLY A 832
PRO A 833
ALA A1210
 None
 0.54A 4qn9B-5theA:
undetectable		 4qn9B-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		3 / 3 ASN A1163
TYR A1169
CYH A1158
 None
 1.08A 5lsuB-5theA:
undetectable		 5lsuB-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5the UNCHARACTERIZED
PROTEIN
(Vanderwaltozyma
polyspora) 		4 / 7 ASP A1003
ARG A1025
GLN A1239
TYR A1250
 None
 1.44A 6g31G-5theA:
undetectable		 6g31G-5theA:
20.48