SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5thz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)
5thz CURJ
(Moorea
producens)
5 / 12 ILE B 204
GLY B 205
GLY B 207
THR B 229
ASN B 277
None
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
None
GOL  B 502 (-4.3A)
0.96A 1nv8A-5thzB:
10.9
1nv8A-5thzB:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
6 / 12 GLU B 203
GLY B 205
GLY B 207
ILE B 231
ASP B 255
ILE B 256
None
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-3.7A)
SAH  B 501 (-3.9A)
SAH  B 501 (-4.3A)
0.65A 1qaoA-5thzB:
9.6
1qaoA-5thzB:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
6 / 12 GLY B 205
GLY B 207
ILE B 231
ASP B 255
ILE B 256
ASN B 277
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-3.7A)
SAH  B 501 (-3.9A)
SAH  B 501 (-4.3A)
GOL  B 502 (-4.3A)
0.91A 1qaoA-5thzB:
9.6
1qaoA-5thzB:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5thz CURJ
(Moorea
producens)
5 / 12 LEU B 121
LEU B  42
GLU B  40
GLY B  36
ALA B 173
None
1.18A 2bm9B-5thzB:
7.8
2bm9B-5thzB:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_1
(HYPOTHETICAL PROTEIN
LMO1582)
5thz CURJ
(Moorea
producens)
4 / 4 THR B 212
THR B 208
ASP B 230
ASP B 255
None
None
SAH  B 501 (-2.7A)
SAH  B 501 (-3.9A)
1.44A 2f8lA-5thzB:
12.0
2f8lA-5thzB:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)
5thz CURJ
(Moorea
producens)
5 / 11 LEU B  90
LEU B  87
ILE B  47
LEU B 316
ASP B 315
None
1.11A 2q6hA-5thzB:
undetectable
2q6hA-5thzB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)
5thz CURJ
(Moorea
producens)
5 / 11 LEU B  90
LEU B  87
ILE B  47
LEU B 316
ASP B 315
None
1.11A 2q72A-5thzB:
undetectable
2q72A-5thzB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)
5thz CURJ
(Moorea
producens)
5 / 12 LEU B  90
LEU B  87
ILE B  47
LEU B 316
ASP B 315
None
1.13A 2qb4A-5thzB:
undetectable
2qb4A-5thzB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)
5thz CURJ
(Moorea
producens)
5 / 11 LEU B  90
LEU B  87
ILE B  47
LEU B 316
ASP B 315
None
1.13A 2qeiA-5thzB:
undetectable
2qeiA-5thzB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)
5thz CURJ
(Moorea
producens)
4 / 6 ILE B 204
LEU B 279
LEU B 254
ASP B 255
None
None
None
SAH  B 501 (-3.9A)
0.96A 2rlfA-5thzB:
undetectable
2rlfD-5thzB:
undetectable
2rlfA-5thzB:
9.14
2rlfD-5thzB:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_1
(HYPOTHETICAL PROTEIN
TTHA0223)
5thz CURJ
(Moorea
producens)
4 / 5 TYR B 169
GLU B 203
ASP B 230
ASP B 255
SAH  B 501 ( 4.1A)
None
SAH  B 501 (-2.7A)
SAH  B 501 (-3.9A)
1.32A 2yqzA-5thzB:
16.4
2yqzA-5thzB:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_1
(HYPOTHETICAL PROTEIN
TTHA0223)
5thz CURJ
(Moorea
producens)
4 / 5 TYR B 169
GLU B 203
ASP B 230
ASP B 255
SAH  B 501 ( 4.1A)
None
SAH  B 501 (-2.7A)
SAH  B 501 (-3.9A)
1.36A 2yqzB-5thzB:
16.3
2yqzB-5thzB:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)
5thz CURJ
(Moorea
producens)
5 / 12 GLU B 203
GLY B 205
TYR B 305
ILE B 231
GLN B 263
None
SAH  B 501 (-3.5A)
None
SAH  B 501 (-3.7A)
None
1.43A 3bwyA-5thzB:
13.1
3bwyA-5thzB:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
5thz CURJ
(Moorea
producens)
4 / 4 GLU B  34
GLY B  36
THR B  37
GLU B  40
None
1.22A 3e9xA-5thzB:
undetectable
3e9xA-5thzB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
5thz CURJ
(Moorea
producens)
5 / 12 SER B 172
TYR B 305
ALA B 173
VAL B  24
MET B 178
None
0.99A 3f8wA-5thzB:
undetectable
3f8wA-5thzB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
5thz CURJ
(Moorea
producens)
5 / 12 SER B 172
TYR B 305
ALA B 173
VAL B  24
MET B 178
None
1.00A 3f8wC-5thzB:
undetectable
3f8wC-5thzB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))
5thz CURJ
(Moorea
producens)
5 / 10 ALA B  69
LEU B  87
VAL B  75
ILE B  47
LEU B 142
None
1.17A 3fl9F-5thzB:
undetectable
3fl9F-5thzB:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
5thz CURJ
(Moorea
producens)
5 / 11 GLY B 205
GLY B 207
ASP B 230
GLU B 257
ALA B 276
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 ( 4.5A)
SAH  B 501 (-3.6A)
1.08A 3g88A-5thzB:
13.4
3g88A-5thzB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
5thz CURJ
(Moorea
producens)
5 / 11 GLY B 205
GLY B 207
ASP B 230
GLU B 257
ALA B 276
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 ( 4.5A)
SAH  B 501 (-3.6A)
1.08A 3g88B-5thzB:
13.3
3g88B-5thzB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
ASP B 230
GLU B 257
ALA B 276
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 ( 4.5A)
SAH  B 501 (-3.6A)
1.07A 3g8bA-5thzB:
13.1
3g8bA-5thzB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
ASP B 230
GLU B 257
ALA B 276
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 ( 4.5A)
SAH  B 501 (-3.6A)
1.09A 3g8bB-5thzB:
12.3
3g8bB-5thzB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)
5thz CURJ
(Moorea
producens)
5 / 12 GLU B  40
LEU B  39
ILE B 317
LEU B 168
TYR B 336
None
1.37A 3ia4A-5thzB:
undetectable
3ia4A-5thzB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)
5thz CURJ
(Moorea
producens)
5 / 10 ALA B  69
LEU B  87
VAL B  75
ILE B  47
LEU B 142
None
1.20A 3jw5B-5thzB:
undetectable
3jw5B-5thzB:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)
5thz CURJ
(Moorea
producens)
5 / 10 SER B  43
LEU B 316
ASP B 315
SER B 311
GLY B  36
None
1.40A 3lsfB-5thzB:
undetectable
3lsfE-5thzB:
undetectable
3lsfB-5thzB:
20.31
3lsfE-5thzB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
3 / 3 GLY B 207
ASP B 230
ASP B 255
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 (-3.9A)
0.29A 3ou7C-5thzB:
15.5
3ou7C-5thzB:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)
5thz CURJ
(Moorea
producens)
5 / 12 GLU B 203
GLY B 205
GLY B 207
THR B 208
ASP B 255
None
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
None
SAH  B 501 (-3.9A)
0.78A 3sglA-5thzB:
11.2
3sglA-5thzB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 209
GLY B 210
ASP B 230
ASP B 255
SAH  B 501 (-3.5A)
SAH  B 501 ( 4.6A)
SAH  B 501 (-3.4A)
SAH  B 501 (-2.7A)
SAH  B 501 (-3.9A)
0.68A 4b17A-5thzB:
8.8
4b17A-5thzB:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
ILE B 204
ASN B 277
VAL B 278
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
None
GOL  B 502 (-4.3A)
SAH  B 501 (-4.1A)
1.03A 4fr0A-5thzB:
14.5
4fr0A-5thzB:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
5thz CURJ
(Moorea
producens)
4 / 7 THR B 164
LEU B 122
GLN B 117
LEU B  42
None
0.95A 4ib4A-5thzB:
undetectable
4ib4A-5thzB:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
ILE B 231
ASP B 255
ILE B 256
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-3.7A)
SAH  B 501 (-3.9A)
SAH  B 501 (-4.3A)
0.77A 4iv0B-5thzB:
15.6
4iv0B-5thzB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
5thz CURJ
(Moorea
producens)
6 / 12 GLY B 205
GLY B 207
ASP B 230
ILE B 231
ASP B 255
ILE B 256
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 (-3.7A)
SAH  B 501 (-3.9A)
SAH  B 501 (-4.3A)
0.79A 4iv8A-5thzB:
16.0
4iv8A-5thzB:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
5thz CURJ
(Moorea
producens)
6 / 12 GLY B 205
GLY B 207
ASP B 230
ILE B 231
ASP B 255
ILE B 256
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 (-3.7A)
SAH  B 501 (-3.9A)
SAH  B 501 (-4.3A)
0.80A 4iv8B-5thzB:
16.0
4iv8B-5thzB:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
ASP B 230
ALA B 276
GLU B 257
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-2.7A)
SAH  B 501 (-3.6A)
SAH  B 501 ( 4.5A)
0.90A 4lg1A-5thzB:
12.2
4lg1A-5thzB:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)
5thz CURJ
(Moorea
producens)
3 / 3 LEU B  42
ASP B  45
TYR B  46
None
0.46A 4qc6B-5thzB:
undetectable
4qc6B-5thzB:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)
5thz CURJ
(Moorea
producens)
3 / 3 GLU B 225
ARG B 200
GLN B 252
None
0.96A 4rtbA-5thzB:
undetectable
4rtbA-5thzB:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 323
LEU B 321
ASP B 230
VAL B 153
PHE B 318
None
None
SAH  B 501 (-2.7A)
None
GOL  B 502 (-3.6A)
1.04A 4wnwA-5thzB:
undetectable
4wnwA-5thzB:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
5 / 9 LEU B  39
GLY B  36
ILE B 317
LEU B 168
THR B 131
None
1.20A 4x3mB-5thzB:
undetectable
4x3mB-5thzB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
THR B 211
ASP B 230
ILE B 256
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-4.8A)
SAH  B 501 (-2.7A)
SAH  B 501 (-4.3A)
0.88A 5bw4A-5thzB:
11.9
5bw4A-5thzB:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
THR B 212
ASP B 230
ILE B 256
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
None
SAH  B 501 (-2.7A)
SAH  B 501 (-4.3A)
1.10A 5bw4A-5thzB:
11.9
5bw4A-5thzB:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
5thz CURJ
(Moorea
producens)
5 / 12 GLY B 205
GLY B 207
THR B 212
ILE B 256
GLU B 257
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
None
SAH  B 501 (-4.3A)
SAH  B 501 ( 4.5A)
1.18A 5bw4A-5thzB:
11.9
5bw4A-5thzB:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)
5thz CURJ
(Moorea
producens)
3 / 3 TYR B 214
LYS B 176
LYS B 170
None
1.23A 5dbyA-5thzB:
undetectable
5dbyA-5thzB:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)
5thz CURJ
(Moorea
producens)
5 / 12 LEU B 134
GLY B 209
PHE B 157
GLY B 205
ASP B 230
None
SAH  B 501 ( 4.6A)
None
SAH  B 501 (-3.5A)
SAH  B 501 (-2.7A)
0.85A 5kb5A-5thzB:
2.9
5kb5A-5thzB:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)
5thz CURJ
(Moorea
producens)
5 / 10 ALA B 239
THR B 208
ALA B 233
GLY B 232
THR B 253
None
1.04A 5lf3H-5thzB:
undetectable
5lf3I-5thzB:
undetectable
5lf3H-5thzB:
18.18
5lf3I-5thzB:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)
5thz CURJ
(Moorea
producens)
5 / 10 ALA B 239
THR B 208
ALA B 233
GLY B 232
THR B 253
None
1.04A 5lf3V-5thzB:
undetectable
5lf3W-5thzB:
undetectable
5lf3V-5thzB:
18.18
5lf3W-5thzB:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
5thz CURJ
(Moorea
producens)
5 / 11 ALA B 239
THR B 208
ALA B 233
GLY B 232
THR B 253
None
0.99A 5lf7H-5thzB:
undetectable
5lf7I-5thzB:
undetectable
5lf7H-5thzB:
18.18
5lf7I-5thzB:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
5thz CURJ
(Moorea
producens)
5 / 11 ALA B 239
THR B 208
ALA B 233
GLY B 232
THR B 253
None
0.98A 5lf7V-5thzB:
undetectable
5lf7W-5thzB:
undetectable
5lf7V-5thzB:
18.18
5lf7W-5thzB:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)
5thz CURJ
(Moorea
producens)
4 / 8 HIS B 280
LEU B 321
GLY B 319
VAL B 314
GOL  B 502 ( 4.7A)
None
None
None
0.96A 5m8rC-5thzB:
undetectable
5m8rC-5thzB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
5thz CURJ
(Moorea
producens)
4 / 5 ASP B 315
PRO B 152
GLU B 322
ARG B  81
None
1.35A 5uxcA-5thzB:
undetectable
5uxcA-5thzB:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)
5thz CURJ
(Moorea
producens)
5 / 10 GLY B 299
GLY B 300
ALA B 297
PRO B   2
HIS B 268
None
1.03A 6e5zA-5thzB:
3.4
6e5zA-5thzB:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)
5thz CURJ
(Moorea
producens)
5 / 12 GLU B 203
ILE B 204
GLY B 205
GLY B 207
ILE B 231
None
None
SAH  B 501 (-3.5A)
SAH  B 501 (-3.3A)
SAH  B 501 (-3.7A)
0.55A 6iftA-5thzB:
9.5
6iftA-5thzB:
21.58