SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ti1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.19A 1q23B-5ti1A:
undetectable		 1q23B-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.17A 1q23C-5ti1A:
undetectable		 1q23C-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 10 SER A  70
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.40A 1q23E-5ti1A:
undetectable		 1q23E-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 10 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.14A 1q23E-5ti1A:
undetectable		 1q23E-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 SER A  70
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.35A 1q23F-5ti1A:
undetectable		 1q23F-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.13A 1q23F-5ti1A:
undetectable		 1q23F-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.21A 1q23I-5ti1A:
undetectable		 1q23I-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.16A 1q23J-5ti1A:
undetectable		 1q23J-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 10 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.13A 1q23K-5ti1A:
undetectable		 1q23K-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.12A 1q23L-5ti1A:
undetectable		 1q23L-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 6 LEU A 250
LEU A 364
PRO A 137
VAL A 138
 None
 1.16A 2dqyC-5ti1A:
undetectable		 2dqyC-5ti1A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 6 ILE A 333
ARG A 400
LEU A 392
LEU A 409
ASP A 407
 None
 1.29A 2rlfA-5ti1A:
undetectable
2rlfD-5ti1A:
undetectable		 2rlfA-5ti1A:
7.21
2rlfD-5ti1A:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 8 ASP A 252
LYS A 272
GLY A 368
GLU A 220
 NA  A 502 ( 3.3A)
MG  A 501 ( 3.3A)
MG  A 501 ( 4.7A)
MG  A 501 (-2.9A)
 0.86A 2ys6A-5ti1A:
undetectable		 2ys6A-5ti1A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 ALA A  62
ASP A  59
PRO A  35
LEU A  86
PRO A 137
 None
 1.33A 3cl9A-5ti1A:
undetectable		 3cl9A-5ti1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 GLY A 368
ASP A 252
ILE A 217
THR A 334
THR A 336
 MG  A 501 ( 4.7A)
NA  A 502 ( 3.3A)
None
None
None
 0.90A 3el4A-5ti1A:
undetectable		 3el4A-5ti1A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 LEU A 115
THR A 114
GLY A  67
ALA A  66
LEU A  69
 None
 1.06A 3p5nA-5ti1A:
undetectable		 3p5nA-5ti1A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 LEU A 115
THR A 114
GLY A  67
ALA A  66
LEU A  69
 None
 1.06A 3p5nB-5ti1A:
undetectable		 3p5nB-5ti1A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 8 TYR A 263
GLN A 259
TYR A 147
TYR A 178
 None
 0.90A 3po7A-5ti1A:
undetectable		 3po7A-5ti1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 PHE A 146
GLY A 177
GLY A 368
SER A 148
ALA A 153
 None
None
MG  A 501 ( 4.7A)
None
None
 1.24A 3sueD-5ti1A:
undetectable		 3sueD-5ti1A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 10 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.16A 3u9fE-5ti1A:
undetectable		 3u9fE-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.14A 3u9fH-5ti1A:
undetectable
3u9fI-5ti1A:
undetectable		 3u9fH-5ti1A:
18.45
3u9fI-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 10 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.16A 3u9fI-5ti1A:
undetectable		 3u9fI-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 10 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.18A 3u9fK-5ti1A:
undetectable		 3u9fK-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.18A 3u9fN-5ti1A:
undetectable
3u9fO-5ti1A:
undetectable		 3u9fN-5ti1A:
18.45
3u9fO-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 9 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.14A 3u9fP-5ti1A:
undetectable		 3u9fP-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 10 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.18A 3u9fR-5ti1A:
undetectable		 3u9fR-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 SER A  79
LEU A 104
VAL A  51
PHE A  36
VAL A 100
 None
 1.24A 3u9fP-5ti1A:
undetectable
3u9fS-5ti1A:
undetectable		 3u9fP-5ti1A:
18.45
3u9fS-5ti1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 4 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.17A 4f3tA-5ti1A:
undetectable		 4f3tA-5ti1A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 12 THR A 144
GLY A 142
ASP A 363
ILE A 225
ASN A 179
 None
 1.33A 4pooB-5ti1A:
undetectable		 4pooB-5ti1A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 4 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.15A 4w5qA-5ti1A:
undetectable		 4w5qA-5ti1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 4 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.19A 4w5rA-5ti1A:
undetectable		 4w5rA-5ti1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 4 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.21A 4w5tA-5ti1A:
undetectable		 4w5tA-5ti1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		3 / 3 VAL A  58
PHE A  36
ARG A 101
 None
 0.95A 4xr4B-5ti1A:
undetectable		 4xr4B-5ti1A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 5 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.20A 4z4cA-5ti1A:
undetectable		 4z4cA-5ti1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 4 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.18A 4z4gA-5ti1A:
undetectable		 4z4gA-5ti1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 8 PHE A  29
GLY A  54
TRP A 281
PHE A  36
 None
 1.00A 5flcB-5ti1A:
undetectable		 5flcB-5ti1A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 6 ARG A 256
ASP A 145
GLY A 368
ASP A 252
 None
MG  A 501 (-2.9A)
MG  A 501 ( 4.7A)
NA  A 502 ( 3.3A)
 1.23A 5hp1C-5ti1A:
undetectable		 5hp1C-5ti1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 4 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.18A 5ki6A-5ti1A:
undetectable		 5ki6A-5ti1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		4 / 6 PHE A  81
VAL A  49
ALA A  61
PHE A  39
 None
 1.17A 5t7bA-5ti1A:
undetectable		 5t7bA-5ti1A:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 LEU A 249
GLY A 368
ILE A 370
PHE A 424
ILE A 316
 None
MG  A 501 ( 4.7A)
None
None
None
 0.97A 6ebzA-5ti1A:
undetectable		 6ebzA-5ti1A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 LEU A 249
GLY A 368
ILE A 370
PHE A 424
ILE A 316
 None
MG  A 501 ( 4.7A)
None
None
None
 0.98A 6ebzB-5ti1A:
undetectable		 6ebzB-5ti1A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 LEU A 249
GLY A 368
ILE A 370
PHE A 424
ILE A 316
 None
MG  A 501 ( 4.7A)
None
None
None
 1.01A 6ebzC-5ti1A:
undetectable		 6ebzC-5ti1A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 LEU A 249
GLY A 368
ILE A 370
PHE A 424
ILE A 316
 None
MG  A 501 ( 4.7A)
None
None
None
 0.96A 6ebzD-5ti1A:
undetectable		 6ebzD-5ti1A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 LEU A 249
GLY A 368
ILE A 370
PHE A 424
ILE A 316
 None
MG  A 501 ( 4.7A)
None
None
None
 0.97A 6gp2A-5ti1A:
undetectable		 6gp2A-5ti1A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5ti1 FUMARYLACETOACETATE
HYDROLASE
(Paraburkholderia
xenovorans) 		5 / 11 LEU A 249
GLY A 368
ILE A 370
PHE A 424
ILE A 316
 None
MG  A 501 ( 4.7A)
None
None
None
 1.04A 6gp2B-5ti1A:
undetectable		 6gp2B-5ti1A:
11.88