SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tir'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 PHE A 205
GLU A  83
LEU A  80
LYS A 209
 None
 1.05A 1rmtB-5tirA:
undetectable		 1rmtB-5tirA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 1v54A-5tirA:
undetectable
1v54C-5tirA:
undetectable		 1v54A-5tirA:
19.46
1v54C-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 1v54N-5tirA:
undetectable
1v54P-5tirA:
undetectable		 1v54N-5tirA:
19.46
1v54P-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 1v55A-5tirA:
undetectable
1v55C-5tirA:
undetectable		 1v55A-5tirA:
19.46
1v55C-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		6 / 12 SER A 129
GLN A 149
LEU A  85
HIS A  78
ILE A  26
ALA A 168
 None
MN  A 301 ( 4.8A)
None
MN  A 301 (-3.4A)
None
None
 1.15A 2bxcA-5tirA:
undetectable		 2bxcA-5tirA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2dyrA-5tirA:
undetectable
2dyrC-5tirA:
undetectable		 2dyrA-5tirA:
19.46
2dyrC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 2dyrN-5tirA:
undetectable
2dyrP-5tirA:
undetectable		 2dyrN-5tirA:
19.46
2dyrP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2dysA-5tirA:
undetectable
2dysC-5tirA:
undetectable		 2dysA-5tirA:
19.46
2dysC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.40A 2dysN-5tirA:
undetectable
2dysP-5tirA:
undetectable		 2dysN-5tirA:
19.46
2dysP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2eijA-5tirA:
undetectable
2eijC-5tirA:
undetectable		 2eijA-5tirA:
19.46
2eijC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2eijN-5tirA:
undetectable
2eijP-5tirA:
undetectable		 2eijN-5tirA:
19.46
2eijP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2eikA-5tirA:
undetectable
2eikC-5tirA:
undetectable		 2eikA-5tirA:
19.46
2eikC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 2eikN-5tirA:
undetectable
2eikP-5tirA:
undetectable		 2eikN-5tirA:
19.46
2eikP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2eilA-5tirA:
undetectable
2eilC-5tirA:
undetectable		 2eilA-5tirA:
19.46
2eilC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2eilN-5tirA:
undetectable
2eilP-5tirA:
undetectable		 2eilN-5tirA:
19.46
2eilP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.39A 2eimA-5tirA:
undetectable
2eimC-5tirA:
undetectable		 2eimA-5tirA:
19.46
2eimC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2eimN-5tirA:
undetectable
2eimP-5tirA:
undetectable		 2eimN-5tirA:
19.46
2eimP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.41A 2einA-5tirA:
undetectable
2einC-5tirA:
2.1		 2einA-5tirA:
19.46
2einC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2einN-5tirA:
undetectable
2einP-5tirA:
undetectable		 2einN-5tirA:
19.46
2einP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		5 / 12 GLY A  73
GLN A 149
HIS A  34
LEU A   8
HIS A  30
 None
MN  A 301 ( 4.8A)
None
None
MN  A 301 (-3.4A)
 1.33A 2prgA-5tirA:
undetectable		 2prgA-5tirA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 2y69A-5tirA:
undetectable
2y69C-5tirA:
undetectable		 2y69A-5tirA:
19.46
2y69C-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 2zxwA-5tirA:
1.8
2zxwC-5tirA:
2.2		 2zxwA-5tirA:
19.46
2zxwC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.41A 2zxwN-5tirA:
2.3
2zxwP-5tirA:
undetectable		 2zxwN-5tirA:
19.46
2zxwP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.45A 3abkA-5tirA:
undetectable
3abkC-5tirA:
undetectable		 3abkA-5tirA:
19.46
3abkC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 3abkN-5tirA:
undetectable
3abkP-5tirA:
undetectable		 3abkN-5tirA:
19.46
3abkP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 3abmN-5tirA:
undetectable
3abmP-5tirA:
undetectable		 3abmN-5tirA:
19.46
3abmP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 3ag1A-5tirA:
1.8
3ag1C-5tirA:
2.2		 3ag1A-5tirA:
19.46
3ag1C-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 3ag1N-5tirA:
undetectable
3ag1P-5tirA:
2.2		 3ag1N-5tirA:
19.46
3ag1P-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 3ag2A-5tirA:
undetectable
3ag2C-5tirA:
2.1		 3ag2A-5tirA:
19.46
3ag2C-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 3ag2N-5tirA:
2.0
3ag2P-5tirA:
undetectable		 3ag2N-5tirA:
19.46
3ag2P-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 3ag3A-5tirA:
2.0
3ag3C-5tirA:
undetectable		 3ag3A-5tirA:
19.46
3ag3C-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 3ag3N-5tirA:
undetectable
3ag3P-5tirA:
undetectable		 3ag3N-5tirA:
19.46
3ag3P-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 3ag4A-5tirA:
undetectable
3ag4C-5tirA:
undetectable		 3ag4A-5tirA:
19.46
3ag4C-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 3ag4N-5tirA:
1.9
3ag4P-5tirA:
2.1		 3ag4N-5tirA:
19.46
3ag4P-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 3asnA-5tirA:
1.8
3asnC-5tirA:
undetectable		 3asnA-5tirA:
19.46
3asnC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		3 / 3 GLN A 195
THR A 192
LEU A 208
 None
 0.52A 3ondA-5tirA:
undetectable		 3ondA-5tirA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		3 / 3 GLN A 195
THR A 192
LEU A 208
 None
 0.52A 3ondB-5tirA:
undetectable		 3ondB-5tirA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 5 ALA A 103
GLU A 194
GLU A 100
ALA A  98
 None
 1.06A 3r9tC-5tirA:
undetectable		 3r9tC-5tirA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 5 PHE A 115
LEU A 123
GLY A 132
VAL A 135
 None
 1.03A 3wrkD-5tirA:
1.3		 3wrkD-5tirA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 ILE A  22
TYR A 180
PHE A  81
ASN A  84
 None
 1.50A 4o7gB-5tirA:
undetectable		 4o7gB-5tirA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 8 PHE A   6
ALA A  45
LEU A  46
GLY A   4
 None
 0.94A 4xk8a-5tirA:
undetectable		 4xk8a-5tirA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 5b1aN-5tirA:
undetectable
5b1aP-5tirA:
2.0		 5b1aN-5tirA:
19.46
5b1aP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 5b1bN-5tirA:
undetectable
5b1bP-5tirA:
2.0		 5b1bN-5tirA:
19.46
5b1bP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 5b3sN-5tirA:
undetectable
5b3sP-5tirA:
undetectable		 5b3sN-5tirA:
19.46
5b3sP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		5 / 10 LEU A 208
GLU A  83
LEU A  80
ARG A 196
LEU A   8
 None
 1.48A 5dxeB-5tirA:
undetectable		 5dxeB-5tirA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 5iy5A-5tirA:
undetectable
5iy5C-5tirA:
undetectable		 5iy5A-5tirA:
19.46
5iy5C-5tirA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 GLU A 156
PRO A 158
GLY A 155
PHE A 205
 None
 0.99A 5jcnB-5tirA:
undetectable		 5jcnB-5tirA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.42A 5x19N-5tirA:
1.2
5x19P-5tirA:
2.2		 5x19N-5tirA:
19.46
5x19P-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.45A 5x1bN-5tirA:
undetectable
5x1bP-5tirA:
2.1		 5x1bN-5tirA:
19.46
5x1bP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 5x1fN-5tirA:
undetectable
5x1fP-5tirA:
undetectable		 5x1fN-5tirA:
19.46
5x1fP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.45A 5zcqN-5tirA:
undetectable
5zcqP-5tirA:
undetectable		 5zcqN-5tirA:
19.46
5zcqP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.43A 6nknA-5tirA:
undetectable
6nknC-5tirA:
2.2		 6nknA-5tirA:
19.46
6nknC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.46A 6nmfN-5tirA:
1.1
6nmfP-5tirA:
undetectable		 6nmfN-5tirA:
19.46
6nmfP-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 6 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.47A 6nmpA-5tirA:
undetectable
6nmpC-5tirA:
undetectable		 6nmpA-5tirA:
19.46
6nmpC-5tirA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tir SUPEROXIDE DISMUTASE
(Trichoderma
reesei) 		4 / 7 HIS A  30
ASP A  16
TYR A  13
HIS A  34
 MN  A 301 (-3.4A)
None
None
None
 1.44A 6nmpN-5tirA:
undetectable
6nmpP-5tirA:
undetectable		 6nmpN-5tirA:
19.46
6nmpP-5tirA:
21.69