SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tiw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 ILE A 158
PHE A 162
LEU A 255
LEU A 249
MET A 242
 None
OAQ  A 302 (-4.6A)
None
None
OAQ  A 302 ( 4.0A)
 1.20A 1dtlA-5tiwA:
undetectable		 1dtlA-5tiwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 THR A  98
TYR A  51
ILE A  56
ILE A  57
ALA A 173
 None
None
None
OAQ  A 302 ( 4.9A)
None
 1.15A 1jtxA-5tiwA:
undetectable		 1jtxA-5tiwA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 4 ASP A 184
LEU A 133
LEU A 138
LEU A 130
 None
 1.31A 1u18A-5tiwA:
undetectable		 1u18A-5tiwA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.05A 1v54A-5tiwA:
undetectable
1v54J-5tiwA:
undetectable		 1v54A-5tiwA:
16.34
1v54J-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		3 / 3 SER A 132
ASP A 100
CYH A 104
 A3P  A 301 (-2.5A)
OAQ  A 302 (-2.5A)
None
 1.16A 2br4E-5tiwA:
undetectable		 2br4E-5tiwA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.04A 2dyrA-5tiwA:
undetectable
2dyrJ-5tiwA:
undetectable		 2dyrA-5tiwA:
16.34
2dyrJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.05A 2dysA-5tiwA:
undetectable
2dysJ-5tiwA:
undetectable		 2dysA-5tiwA:
16.34
2dysJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.06A 2dysN-5tiwA:
undetectable
2dysW-5tiwA:
undetectable		 2dysN-5tiwA:
16.34
2dysW-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.05A 2eilA-5tiwA:
undetectable
2eilJ-5tiwA:
undetectable		 2eilA-5tiwA:
16.34
2eilJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.03A 2zxwA-5tiwA:
undetectable
2zxwJ-5tiwA:
undetectable		 2zxwA-5tiwA:
16.34
2zxwJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 7 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.02A 2zxwN-5tiwA:
undetectable
2zxwW-5tiwA:
undetectable		 2zxwN-5tiwA:
16.34
2zxwW-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 7 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.03A 3ablA-5tiwA:
undetectable
3ablJ-5tiwA:
undetectable		 3ablA-5tiwA:
16.34
3ablJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.06A 3abmA-5tiwA:
undetectable
3abmJ-5tiwA:
undetectable		 3abmA-5tiwA:
16.34
3abmJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 1.05A 3asoA-5tiwA:
undetectable
3asoJ-5tiwA:
undetectable		 3asoA-5tiwA:
16.34
3asoJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 CYH A 220
SER A 218
HIS A 210
TYR A 233
LEU A 208
 None
 1.23A 3g9eA-5tiwA:
undetectable		 3g9eA-5tiwA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 ILE A  23
LEU A 120
LYS A 118
ILE A  45
ILE A  96
 None
 1.21A 3ql3A-5tiwA:
undetectable		 3ql3A-5tiwA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_A_VK3A202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 5 TYR A  51
TYR A  95
LEU A  92
TRP A  67
 None
 1.32A 4f8yA-5tiwA:
undetectable
4f8yB-5tiwA:
undetectable		 4f8yA-5tiwA:
20.68
4f8yB-5tiwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 TRP A  67
ASN A  93
TYR A  51
TYR A  95
 None
 1.37A 4f8yA-5tiwA:
undetectable
4f8yB-5tiwA:
undetectable		 4f8yA-5tiwA:
20.68
4f8yB-5tiwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 TRP A  67
TYR A  51
TYR A  95
LEU A  92
 None
 1.40A 4f8yA-5tiwA:
undetectable
4f8yB-5tiwA:
undetectable		 4f8yA-5tiwA:
20.68
4f8yB-5tiwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 7 TYR A  51
TYR A  95
LEU A  92
TRP A  67
 None
 1.34A 4f8yC-5tiwA:
undetectable
4f8yD-5tiwA:
undetectable		 4f8yC-5tiwA:
20.68
4f8yD-5tiwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 5 TRP A  67
TYR A  51
TYR A  95
LEU A  92
 None
 1.38A 4f8yC-5tiwA:
undetectable
4f8yD-5tiwA:
undetectable		 4f8yC-5tiwA:
20.68
4f8yD-5tiwA:
20.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
HIS A  52
LEU A 101
VAL A 137
THR A 243
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
 1.18A 4mubA-5tiwA:
39.6		 4mubA-5tiwA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 12 PRO A  31
HIS A  52
MET A  53
LEU A 101
VAL A 137
GLY A 152
ASP A 153
PHE A 162
MET A 242
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.5A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.38A 4mubA-5tiwA:
39.6		 4mubA-5tiwA:
75.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 SER A 254
LEU A 255
ASP A 256
LEU A 249
 None
 0.88A 4wozA-5tiwA:
undetectable
4wozB-5tiwA:
undetectable		 4wozA-5tiwA:
22.05
4wozB-5tiwA:
22.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 12 HIS A  52
MET A  53
ILE A  57
LEU A 101
VAL A 137
GLY A 152
PHE A 162
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.5A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.48A 5byjA-5tiwA:
39.7		 5byjA-5tiwA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
HIS A  52
LEU A 101
VAL A 137
THR A 243
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
 1.16A 5bykA-5tiwA:
39.8		 5bykA-5tiwA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		11 / 12 PRO A  31
HIS A  52
MET A  53
ILE A  57
LEU A 101
VAL A 136
VAL A 137
LEU A 156
PHE A 162
MET A 242
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.37A 5bykA-5tiwA:
39.8		 5bykA-5tiwA:
75.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 11 LEU A 208
ILE A  45
TYR A  46
GLN A  24
ILE A  96
 None
 1.16A 5d75A-5tiwA:
undetectable		 5d75A-5tiwA:
18.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		12 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
VAL A 136
VAL A 137
ILE A 149
LEU A 156
PHE A 162
LEU A 245
THR A 246
LEU A 249
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
None
 0.01A 5tiwA-5tiwA:
45.7		 5tiwA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 12 MET A  53
ILE A  57
ASP A 100
VAL A 137
ILE A 149
ASP A 153
PHE A 162
SER A 166
LEU A 245
THR A 246
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.56A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
ASP A 100
LEU A 101
SER A 169
LEU A 156
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
None
None
 1.30A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
ILE A  56
ASP A 100
LEU A 101
SER A 169
 OAQ  A 302 (-4.7A)
None
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
None
 1.19A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
LEU A 170
VAL A 137
ILE A 149
LEU A 156
 OAQ  A 302 (-4.7A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
None
 1.33A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		11 / 12 PRO A  31
MET A  53
ILE A  57
ASP A 100
LEU A 101
VAL A 137
ILE A 149
ASP A 153
PHE A 162
LEU A 245
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.32A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
LEU A 265
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
 1.31A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		9 / 9 PRO A  31
MET A  53
LEU A 101
VAL A 137
LEU A 138
ILE A 149
ASP A 153
PHE A 162
SER A 166
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
 0.31A 5tixA-5tiwA:
42.9		 5tixA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 10 PRO A  31
MET A  53
ILE A  57
LEU A 101
VAL A 137
LEU A 138
ASP A 153
PHE A 162
SER A 166
GLU A 167
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
None
 0.31A 5tixB-5tiwA:
43.0		 5tixB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 11 MET A  53
ILE A  57
ASP A 100
VAL A 137
ASP A 153
PHE A 162
SER A 166
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.50A 5tiyA-5tiwA:
43.0		 5tiyA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 11 PRO A  31
MET A  53
ILE A  57
ASP A 100
VAL A 137
ASP A 153
PHE A 162
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.22A 5tiyA-5tiwA:
43.0		 5tiyA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		9 / 10 MET A  53
ILE A  57
ASP A 100
LEU A 101
VAL A 137
ASP A 153
PHE A 162
MET A 242
THR A 246
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.46A 6b4yA-5tiwA:
39.5		 6b4yA-5tiwA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		6 / 12 PRO A  31
HIS A  52
ASP A 100
LEU A 101
VAL A 137
THR A 243
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
 1.10A 6b50A-5tiwA:
39.7		 6b50A-5tiwA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		12 / 12 PRO A  31
HIS A  52
MET A  53
ASP A 100
LEU A 101
VAL A 136
VAL A 137
ASP A 153
PHE A 162
SER A 166
MET A 242
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.51A 6b50A-5tiwA:
39.7		 6b50A-5tiwA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		6 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
SER A 166
LEU A 265
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-3.5A)
None
 1.44A 6b52A-5tiwA:
42.9		 6b52A-5tiwA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		12 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
VAL A 136
VAL A 137
LEU A 156
PHE A 162
SER A 166
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.29A 6b52A-5tiwA:
42.9		 6b52A-5tiwA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		11 / 12 MET A  53
ILE A  57
ASP A 100
LEU A 101
VAL A 137
ASP A 153
LEU A 156
PHE A 162
MET A 242
THR A 246
LEU A 249
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
None
 0.36A 6b54A-5tiwA:
42.6		 6b54A-5tiwA:
99.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		3 / 3 ILE A  57
ASN A  36
CYH A  50
 OAQ  A 302 ( 4.9A)
None
None
 0.82A 6bp4A-5tiwA:
undetectable		 6bp4A-5tiwA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 8 TYR A 233
THR A  35
CYH A  50
LEU A 120
 None
A3P  A 301 (-2.8A)
None
None
 1.21A 6cnjD-5tiwA:
undetectable
6cnjE-5tiwA:
undetectable		 6cnjD-5tiwA:
13.44
6cnjE-5tiwA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 6 PHE A 174
LEU A 170
ALA A 173
THR A  33
 None
 0.97A 6f88A-5tiwA:
undetectable		 6f88A-5tiwA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 7 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 0.95A 6nmfA-5tiwA:
undetectable
6nmfJ-5tiwA:
undetectable		 6nmfA-5tiwA:
16.34
6nmfJ-5tiwA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		4 / 7 LEU A  92
ARG A  82
MET A 113
THR A 112
 None
 0.96A 6nmpA-5tiwA:
undetectable
6nmpJ-5tiwA:
undetectable		 6nmpA-5tiwA:
16.34
6nmpJ-5tiwA:
12.65