SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 5 ASP A 305
HIS A 309
HIS A 353
HIS A 486
ZN  A 602 (-2.1A)
ZN  A 602 (-3.2A)
ZN  A 601 (-3.2A)
ZN  A 602 (-3.3A)
0.37A 1ei6A-5tj3A:
25.6
1ei6A-5tj3A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 8 ASP A  38
ASP A 305
HIS A 309
HIS A 353
HIS A 486
ZN  A 601 (-2.2A)
ZN  A 602 (-2.1A)
ZN  A 602 (-3.2A)
ZN  A 601 (-3.2A)
ZN  A 602 (-3.3A)
0.41A 1ei6C-5tj3A:
25.7
1ei6C-5tj3A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 7 LEU A  45
SER A  66
SER A 510
ASN A  68
None
1.15A 1ig3A-5tj3A:
2.1
1ig3B-5tj3A:
2.0
1ig3A-5tj3A:
19.02
1ig3B-5tj3A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 8 GLY A  53
ARG A 327
LEU A 323
ASP A 331
None
0.86A 1jg4A-5tj3A:
undetectable
1jg4A-5tj3A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 6 ARG A 406
GLY A 465
ASP A 466
TYR A 459
None
1.13A 1kf6M-5tj3A:
undetectable
1kf6N-5tj3A:
undetectable
1kf6M-5tj3A:
19.94
1kf6N-5tj3A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 THR A 439
LEU A 427
PHE A 372
ALA A 396
ALA A 397
None
1.16A 1q23A-5tj3A:
undetectable
1q23B-5tj3A:
undetectable
1q23A-5tj3A:
15.91
1q23B-5tj3A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 10 ALA A 535
ALA A 520
VAL A  32
LEU A 527
ASP A 144
None
1.30A 1rlbE-5tj3A:
undetectable
1rlbE-5tj3A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 6 PHE A 296
VAL A  32
LEU A 346
PHE A  87
SER A 350
None
1.43A 1wrlB-5tj3A:
undetectable
1wrlB-5tj3A:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 7 ALA A 330
ASP A 326
GLY A  56
GLY A  55
None
0.57A 2c49B-5tj3A:
undetectable
2c49B-5tj3A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 7 PHE A  57
ARG A 324
THR A 273
LEU A 276
None
1.08A 2eikA-5tj3A:
undetectable
2eikJ-5tj3A:
undetectable
2eikA-5tj3A:
22.47
2eikJ-5tj3A:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 ILE A 470
VAL A 455
VAL A 402
ARG A 406
LEU A 416
None
1.14A 2g78A-5tj3A:
undetectable
2g78A-5tj3A:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 6 ARG A  28
SER A 154
LEU A 146
GLY A 147
None
1.03A 2j2pA-5tj3A:
undetectable
2j2pC-5tj3A:
undetectable
2j2pA-5tj3A:
18.48
2j2pC-5tj3A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 8 ALA A 520
THR A 141
PHE A  87
THR A  84
None
1.23A 2kotB-5tj3A:
undetectable
2kotB-5tj3A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
3 / 3 ARG A  47
VAL A  37
THR A 304
None
0.81A 2nmzA-5tj3A:
undetectable
2nmzA-5tj3A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 7 ILE A 540
PRO A  29
GLY A 504
TRP A 503
None
1.05A 2pnjB-5tj3A:
undetectable
2pnjB-5tj3A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 10 ALA A 279
LEU A 329
LEU A 276
ASN A 272
LEU A  35
None
1.20A 2riwA-5tj3A:
undetectable
2riwB-5tj3A:
undetectable
2riwA-5tj3A:
20.72
2riwB-5tj3A:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
3 / 3 TYR A 322
ASP A  43
HIS A 353
None
None
ZN  A 601 (-3.2A)
0.89A 3e23A-5tj3A:
undetectable
3e23A-5tj3A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 8 ASP A 253
ASP A 257
THR A 268
PRO A 269
None
0.62A 3el0A-5tj3A:
undetectable
3el0A-5tj3A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_1
(GLUCOCORTICOID
RECEPTOR)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 10 LEU A 336
ASN A 334
MET A  60
MET A 501
LEU A 349
None
1.48A 3h52B-5tj3A:
undetectable
3h52B-5tj3A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 ILE A  81
VAL A  78
ILE A  72
VAL A  75
PRO A  76
None
TPO  A  79 ( 2.9A)
None
None
None
1.05A 3kpdC-5tj3A:
undetectable
3kpdC-5tj3A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 8 ILE A  86
PHE A 348
THR A 522
VAL A  70
None
0.70A 3me6B-5tj3A:
undetectable
3me6B-5tj3A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
3 / 3 ASP A 253
THR A 268
PRO A 269
None
0.59A 3tkgD-5tj3A:
undetectable
3tkgD-5tj3A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 11 GLY A 289
ASP A 295
SER A 154
PRO A  29
LEU A 527
ZN  A 604 ( 4.9A)
ZN  A 604 (-2.4A)
None
None
None
1.24A 3v8vB-5tj3A:
undetectable
3v8vB-5tj3A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 11 ILE A 167
ALA A 177
GLY A 176
GLY A 123
HIS A 132
None
0.95A 4e47A-5tj3A:
undetectable
4e47A-5tj3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 11 ILE A 167
ALA A 177
GLY A 176
GLY A 123
HIS A 132
None
0.93A 4e47B-5tj3A:
undetectable
4e47B-5tj3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 11 ILE A 167
ALA A 177
GLY A 176
GLY A 123
HIS A 132
None
0.94A 4jdsA-5tj3A:
undetectable
4jdsA-5tj3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 11 ILE A 167
ALA A 177
GLY A 176
GLY A 123
HIS A 132
None
0.95A 4jdsB-5tj3A:
undetectable
4jdsB-5tj3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 ILE A 167
ALA A 177
GLY A 176
GLY A 123
HIS A 132
None
1.01A 4jlgA-5tj3A:
undetectable
4jlgA-5tj3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
3 / 3 ILE A 470
ASP A 473
ARG A 454
None
0.83A 4pstA-5tj3A:
undetectable
4pstA-5tj3A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 GLY A  89
LEU A 168
SER A 533
ILE A  86
ALA A 520
None
1.03A 4qtuB-5tj3A:
undetectable
4qtuB-5tj3A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 7 SER A 315
PHE A 249
GLU A 317
GLU A 238
None
None
ZN  A 603 (-2.3A)
ZN  A 603 (-2.7A)
1.32A 4xzkA-5tj3A:
undetectable
4xzkA-5tj3A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 8 PRO A 169
PHE A  87
SER A  85
TYR A  74
None
1.23A 5amiB-5tj3A:
undetectable
5amiB-5tj3A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 7 THR A 252
TYR A 251
PRO A 250
THR A 248
None
1.26A 5b6iA-5tj3A:
undetectable
5b6iA-5tj3A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 9 GLY A 312
SER A 315
GLU A 317
ASN A 310
ALA A 355
None
None
ZN  A 603 (-2.3A)
None
None
1.42A 5entC-5tj3A:
undetectable
5entC-5tj3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 11 VAL A 318
LEU A 241
TYR A 251
PHE A 249
SER A 315
None
1.50A 5g6sA-5tj3A:
undetectable
5g6sG-5tj3A:
undetectable
5g6sA-5tj3A:
20.55
5g6sG-5tj3A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 ILE A  86
VAL A 523
GLU A 542
VAL A  32
GLY A  64
None
0.99A 5igjA-5tj3A:
undetectable
5igjA-5tj3A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
3 / 3 ASP A 320
ASN A 225
GLN A 226
None
0.61A 5k7uA-5tj3A:
1.4
5k7uA-5tj3A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 ILE A 265
SER A 166
HIS A  83
PHE A 180
GLY A 271
None
None
TPO  A  79 ( 4.1A)
None
None
1.08A 5l6eA-5tj3A:
undetectable
5l6eA-5tj3A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 12 ALA A 520
ILE A 544
ILE A 540
PHE A 500
VAL A  32
None
1.27A 5uanB-5tj3A:
undetectable
5uanB-5tj3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
3 / 3 TYR A 227
ASP A 233
ASP A 320
None
ZN  A 603 (-3.4A)
None
0.85A 5x6yA-5tj3A:
undetectable
5x6yA-5tj3A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 5 GLY A  53
ASP A 326
ARG A 327
GLN A 226
None
1.27A 5zrfB-5tj3A:
undetectable
5zrfB-5tj3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
5 / 11 VAL A 157
ALA A 282
TRP A 200
THR A 275
ALA A 279
None
1.40A 6dk1C-5tj3A:
undetectable
6dk1C-5tj3A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica)
4 / 5 GLY A  89
THR A 517
HIS A  95
SER A  93
None
1.11A 6jmjA-5tj3A:
undetectable
6jmjA-5tj3A:
14.60