SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tjf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 5tjf ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		6 / 12 THR B  33
GLY B  29
ARG B  28
ALA B   4
GLY B  99
ILE B   5
 None
 1.41A 1bx4A-5tjfB:
undetectable		 1bx4A-5tjfB:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		3 / 3 ASP B 100
THR B   6
GLU A 106
 None
 0.77A 1pj7A-5tjfB:
undetectable		 1pj7A-5tjfB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5tjf ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 12 THR B 126
ILE B 156
TYR B 116
ILE B 123
LEU B 112
 CYC  B 201 (-2.8A)
None
CYC  B 201 ( 4.1A)
PEG  B 203 (-3.1A)
CYC  B 201 (-4.4A)
 1.01A 1z9hD-5tjfB:
undetectable		 1z9hD-5tjfB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
(Gracilaria
chilensis) 		4 / 6 LEU A 141
ILE A  96
ARG A  38
ILE A  42
 None
 0.96A 2q8hA-5tjfA:
undetectable		 2q8hA-5tjfA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		3 / 3 LYS A  27
ARG B  39
VAL B  38
 None
PEG  B 202 (-2.4A)
None
 1.00A 2r2vC-5tjfA:
undetectable
2r2vD-5tjfA:
undetectable		 2r2vC-5tjfA:
13.89
2r2vD-5tjfA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		4 / 6 LEU A  18
SER B  41
TYR A  17
ALA B  40
 None
 1.12A 3rd0A-5tjfA:
2.4		 3rd0A-5tjfA:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
(Gracilaria
chilensis) 		5 / 11 ASP A 145
ILE A  96
GLY A  33
ILE A  42
ILE A  39
 None
 1.15A 3s53B-5tjfA:
undetectable		 3s53B-5tjfA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
(Gracilaria
chilensis) 		4 / 8 GLN A 161
ILE A 123
GLY A 129
GLU A 128
 None
None
CYC  A 201 ( 4.6A)
None
 0.96A 4fgjA-5tjfA:
undetectable
4fgjB-5tjfA:
undetectable		 4fgjA-5tjfA:
20.85
4fgjB-5tjfA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 11 LEU B  97
ARG B  37
SER B  41
VAL A  30
LEU A  23
 None
NA  B 213 (-3.0A)
None
None
None
 1.31A 4or0B-5tjfB:
undetectable		 4or0B-5tjfB:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5tjf ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 7 THR B 137
ALA B  40
THR B  43
ALA B  42
THR B  93
 None
None
NA  B 209 (-3.8A)
NA  B 209 ( 3.7A)
None
 1.29A 4qw0K-5tjfB:
undetectable		 4qw0K-5tjfB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5tjf ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 7 THR B 137
ALA B  40
THR B  43
ALA B  42
THR B  93
 None
None
NA  B 209 (-3.8A)
NA  B 209 ( 3.7A)
None
 1.29A 4qw0Y-5tjfB:
undetectable		 4qw0Y-5tjfB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 12 ILE B   9
PRO A 103
ASP A 100
ALA A  98
SER B  23
 None
 1.29A 4uroC-5tjfB:
undetectable		 4uroC-5tjfB:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
(Gracilaria
chilensis) 		4 / 4 TYR A 116
THR A 121
GLY A 125
LEU A  85
 CYC  A 201 (-4.6A)
CYC  A 201 (-3.7A)
CYC  A 201 (-3.0A)
CYC  A 201 ( 3.6A)
 1.25A 4w5nA-5tjfA:
undetectable		 4w5nA-5tjfA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 12 ALA B  98
GLY B  34
SER A   7
ASP A  12
ARG B 107
 None
NA  B 208 ( 4.4A)
None
CL  B 216 ( 4.7A)
CL  B 216 ( 3.1A)
 1.31A 5zvgA-5tjfB:
undetectable		 5zvgA-5tjfB:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 12 ALA B  98
GLY B  34
SER A   7
ASP A  12
ARG B 107
 None
NA  B 208 ( 4.4A)
None
CL  B 216 ( 4.7A)
CL  B 216 ( 3.1A)
 1.30A 5zvgB-5tjfB:
undetectable		 5zvgB-5tjfB:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 10 GLY A  95
ASP B   3
TYR B  30
VAL B  38
GLU B  35
 None
None
None
None
PEG  B 202 ( 2.8A)
 1.32A 6cgdA-5tjfA:
1.6		 6cgdA-5tjfA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 10 LEU B  19
LEU A  89
ASP A  86
ILE B   9
PRO A 103
 None
 1.37A 6dlzB-5tjfB:
2.1
6dlzC-5tjfB:
undetectable		 6dlzB-5tjfB:
19.15
6dlzC-5tjfB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 11 ILE B   9
PRO A 103
LEU B  19
LEU A  89
ASP A  86
 None
 1.38A 6dlzA-5tjfB:
undetectable
6dlzD-5tjfB:
2.1		 6dlzA-5tjfB:
19.15
6dlzD-5tjfB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 10 LEU B  19
LEU A  89
ASP A  86
ILE B   9
PRO A 103
 None
 1.37A 6dm1B-5tjfB:
2.1
6dm1C-5tjfB:
undetectable		 6dm1B-5tjfB:
19.15
6dm1C-5tjfB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 11 ILE B   9
PRO A 103
LEU B  19
LEU A  89
ASP A  86
 None
 1.38A 6dm1A-5tjfB:
undetectable
6dm1D-5tjfB:
2.1		 6dm1A-5tjfB:
19.15
6dm1D-5tjfB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 10 LEU B  19
LEU A  89
ASP A  86
ILE B   9
PRO A 103
 None
 1.34A 6dm2B-5tjfB:
undetectable
6dm2C-5tjfB:
undetectable		 6dm2B-5tjfB:
19.15
6dm2C-5tjfB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 10 ILE B   9
PRO A 103
LEU B  19
LEU A  89
ASP A  86
 None
 1.35A 6dm2A-5tjfB:
undetectable
6dm2D-5tjfB:
undetectable		 6dm2A-5tjfB:
19.15
6dm2D-5tjfB:
19.15