SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tjj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		4 / 4 ARG A 145
ALA A 191
ALA A 203
GLU A 196
 None
 1.24A 1e7bA-5tjjA:
undetectable		 1e7bA-5tjjA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		4 / 6 SER A  56
VAL A  55
GLY A  67
LEU A  70
 None
 1.01A 1fduD-5tjjA:
undetectable		 1fduD-5tjjA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		3 / 3 ALA A 245
VAL A 247
TRP A 250
 None
 0.85A 1nt5A-5tjjA:
undetectable		 1nt5A-5tjjA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		3 / 3 ALA A 245
VAL A 247
TRP A 250
 None
 0.85A 1nt5B-5tjjA:
undetectable		 1nt5B-5tjjA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		5 / 12 SER A  56
ARG A  20
LEU A  35
ILE A  31
SER A  26
 None
 1.25A 2fj1A-5tjjA:
2.1		 2fj1A-5tjjA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		4 / 8 VAL A  37
ARG A  13
TYR A  64
VAL A  14
 None
 1.30A 2y05A-5tjjA:
undetectable
2y05B-5tjjA:
undetectable		 2y05A-5tjjA:
22.19
2y05B-5tjjA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		5 / 12 VAL A 218
CYH A 221
SER A 220
ALA A 236
THR A  98
 None
 1.05A 3a35B-5tjjA:
undetectable		 3a35B-5tjjA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		5 / 12 VAL A 218
CYH A 221
SER A 220
ALA A 236
THR A  98
 None
 1.05A 3a3bA-5tjjA:
undetectable		 3a3bA-5tjjA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		3 / 3 TYR A  69
LEU A  17
LYS A  16
 None
 0.56A 3sueD-5tjjA:
undetectable		 3sueD-5tjjA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Alicyclobacillus
acidocaldarius) 		5 / 11 LEU A 222
VAL A 130
PHE A 136
SER A 220
PHE A 143
 None
 1.31A 4evrA-5tjjA:
undetectable		 4evrA-5tjjA:
22.91