SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		4 / 4 VAL A 345
PHE A 393
SER A 390
VAL A 388
 None
 1.45A 1e7cA-5tjtA:
undetectable		 1e7cA-5tjtA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		4 / 8 ILE A 347
MET A 288
THR A 289
LEU A 300
 None
 0.94A 2eikN-5tjtA:
undetectable
2eikW-5tjtA:
undetectable		 2eikN-5tjtA:
21.23
2eikW-5tjtA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		5 / 11 LEU A 271
LEU A 275
ARG A 272
VAL A 421
ILE A 255
 None
 1.26A 2q6hA-5tjtA:
undetectable		 2q6hA-5tjtA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		5 / 11 LEU A 271
LEU A 275
ARG A 272
VAL A 421
ILE A 255
 None
 1.26A 2qeiA-5tjtA:
undetectable		 2qeiA-5tjtA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		4 / 6 ILE A 347
MET A 288
THR A 289
LEU A 300
 None
 0.99A 3wg7N-5tjtA:
undetectable
3wg7W-5tjtA:
undetectable		 3wg7N-5tjtA:
21.23
3wg7W-5tjtA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		3 / 3 GLN A 187
ILE A 283
HIS A 279
 None
 0.66A 5z12B-5tjtA:
undetectable		 5z12B-5tjtA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		4 / 6 ILE A 347
MET A 288
THR A 289
LEU A 300
 None
 0.99A 5z86N-5tjtA:
undetectable
5z86W-5tjtA:
undetectable		 5z86N-5tjtA:
21.23
5z86W-5tjtA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tjt MAJOR CAPSID PROTEIN
(Escherichia
virus
T5) 		4 / 6 ILE A 347
MET A 288
THR A 289
LEU A 300
 None
 0.98A 5zcoN-5tjtA:
undetectable
5zcoW-5tjtA:
undetectable		 5zcoN-5tjtA:
21.23
5zcoW-5tjtA:
13.49