SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tk6 OXSA PROTEIN
(Bacillus
megaterium) 		4 / 6 LEU A   5
TYR A  65
THR A 112
LEU A 109
 None
 1.05A 2dyrA-5tk6A:
undetectable
2dyrJ-5tk6A:
undetectable		 2dyrA-5tk6A:
15.89
2dyrJ-5tk6A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5tk6 OXSA PROTEIN
(Bacillus
megaterium) 		4 / 6 ASN A  55
ILE A 127
ILE A 124
VAL A 128
 None
 0.99A 4olmA-5tk6A:
2.2		 4olmA-5tk6A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tk6 OXSA PROTEIN
(Bacillus
megaterium) 		4 / 6 LEU A   5
TYR A  65
THR A 112
LEU A 109
 None
 1.09A 5x1fA-5tk6A:
undetectable
5x1fJ-5tk6A:
undetectable		 5x1fA-5tk6A:
15.89
5x1fJ-5tk6A:
16.27