SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tkw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_B_SVRB501_1 (PHOSPHOLIPASE A2)	5tkw	TYPE II SECRETION SYSTEM PROTEIN L (Klebsiella pneumoniae)	4 / 4	SER A 47 PRO A 48 PHE A 49 PRO A 50	None	1.15A	3bjwA-5tkwA: undetectable	3bjwA-5tkwA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF502_2 (PHOSPHOLIPASE A2)	5tkw	TYPE II SECRETION SYSTEM PROTEIN L (Klebsiella pneumoniae)	4 / 5	SER A 47 PRO A 48 PHE A 49 PRO A 50	None	1.17A	3bjwC-5tkwA: undetectable	3bjwC-5tkwA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_H_SVRH504_1 (PHOSPHOLIPASE A2)	5tkw	TYPE II SECRETION SYSTEM PROTEIN L (Klebsiella pneumoniae)	4 / 4	SER A 47 PRO A 48 PHE A 49 PRO A 50	None	1.14A	3bjwD-5tkwA: undetectable	3bjwD-5tkwA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_B_CELB602_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5tkw	TYPE II SECRETION SYSTEM PROTEIN L (Klebsiella pneumoniae)	5 / 12	LEU A 52 LEU A 135 ALA A 29 GLY A 39 LEU A 23	None	1.08A	5jw1B-5tkwA: undetectable	5jw1B-5tkwA: 16.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJW_B_SVRB501_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","5tkw","TYPE II SECRETION SYSTEM PROTEIN L","Klebsiella pneumoniae",4,"SER A  47;PRO A  48;PHE A  49;PRO A  50","None","1.15A","3bjwA-5tkwA:undetectable","3bjwA-5tkwA:17.75"],["3BJW_F_SVRF502_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","5tkw","TYPE II SECRETION SYSTEM PROTEIN L","Klebsiella pneumoniae",4,"SER A  47;PRO A  48;PHE A  49;PRO A  50","None","1.17A","3bjwC-5tkwA:undetectable","3bjwC-5tkwA:17.75"],["3BJW_H_SVRH504_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","5tkw","TYPE II SECRETION SYSTEM PROTEIN L","Klebsiella pneumoniae",4,"SER A  47;PRO A  48;PHE A  49;PRO A  50","None","1.14A","3bjwD-5tkwA:undetectable","3bjwD-5tkwA:17.75"],["5JW1_B_CELB602_1","PROSTAGLANDIN G\/H SYNTHASE 2","5tkw","TYPE II SECRETION SYSTEM PROTEIN L","Klebsiella pneumoniae",5,"LEU A  52;LEU A 135;ALA A  29;GLY A  39;LEU A  23","None","1.08A","5jw1B-5tkwA:undetectable","5jw1B-5tkwA:16.20"]]