SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tky'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A29_A_TFPA154_1 (CALMODULIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 10	GLU A 121 ALA A 124 LEU A 515 GLU A 519 GLU A 521	None	1.38A	1a29A-5tkyA: undetectable	1a29A-5tkyA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4S_A_TPVA201_1 (PROTEIN (HIV-1 PROTEASE))	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 10	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.84A	1d4sA-5tkyA: undetectable	1d4sA-5tkyA: 11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXG_A_ACRA442_1 (ALPHA AMYLASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 11	GLY A 207 GLY A 234 GLN A 235 GLY A 342 ASP A 203	ATP A 700 (-3.6A) ATP A 700 ( 4.4A) None ATP A 700 (-3.3A) MG A 701 ( 4.5A)	1.08A	1mxgA-5tkyA: undetectable	1mxgA-5tkyA: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_A_CHDA501_0 (FERROCHELATASE, MITOCHONDRIAL)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 267 PHE A 297 LEU A 257 ILE A 301 SER A 258	None	1.07A	2po5A-5tkyA: undetectable	2po5A-5tkyA: 19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6O_B_SAMB500_0 (HYPOTHETICAL PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 6	ASP A 203 VAL A 341 PRO A 150 THR A 148	MG A 701 ( 4.5A) None None None	1.38A	2q6oB-5tkyA: undetectable	2q6oB-5tkyA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R2V_D_ACTD37_0 (GCN4 LEUCINE ZIPPER)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	3 / 3	LYS A 604 ARG A 553 VAL A 554	None	1.01A	2r2vC-5tkyA: undetectable 2r2vD-5tkyA: undetectable	2r2vC-5tkyA: 4.35 2r2vD-5tkyA: 4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3K_A_SAMA1254_0 (ESSENTIAL FOR MITOTIC GROWTH 1)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 10	LEU A 257 GLY A 259 LEU A 291 SER A 290 ALA A 263	None	0.71A	2v3kA-5tkyA: undetectable	2v3kA-5tkyA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRZ_A_ACTA1470_0 (DEOXYRIBODIPYRIMIDIN E PHOTOLYASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 349 ALA A 311 ASP A 308 GLU A 307	None	1.37A	2xrzA-5tkyA: undetectable	2xrzA-5tkyA: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CYW_A_017A201_1 (HIV-1 PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.78A	3cywA-5tkyA: undetectable	3cywA-5tkyA: 10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D20_A_017A201_2 (HIV-1 PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.89A	3d20B-5tkyA: undetectable	3d20B-5tkyA: 9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKT_D_017D200_2 (PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 11	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.86A	3ektD-5tkyA: undetectable	3ektD-5tkyA: 10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3006_1 (TRANSCRIPTIONAL REGULATOR TCAR)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 6	ASN A 454 ILE A 414 GLU A 456 ASN A 458	None	1.38A	3kp6A-5tkyA: 0.3 3kp6B-5tkyA: undetectable	3kp6A-5tkyA: 14.29 3kp6B-5tkyA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LZS_A_017A200_2 (HIV-1 PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.90A	3lzsB-5tkyA: undetectable	3lzsB-5tkyA: 11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LZU_A_017A200_1 (HIV-1 PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.87A	3lzuA-5tkyA: undetectable	3lzuA-5tkyA: 12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_A_DR7A100_1 (HIV-1 PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.86A	3oxxA-5tkyA: undetectable	3oxxA-5tkyA: 12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9S_C_BEZC264_0 (CARNITINYL-COA DEHYDRATASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 6	ALA A 582 ILE A 551 LEU A 547 ALA A 602	None	0.81A	3r9sC-5tkyA: undetectable	3r9sC-5tkyA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3M_A_DLUA398_1 (PFV INTEGRASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 8	ASP A 210 GLY A 228 TYR A 202 GLU A 178	None None None MG A 701 ( 3.7A)	0.90A	3s3mA-5tkyA: 3.5	3s3mA-5tkyA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3N_A_DLUA398_1 (PFV INTEGRASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 8	ASP A 210 GLY A 228 TYR A 202 GLU A 178	None None None MG A 701 ( 3.7A)	0.91A	3s3nA-5tkyA: 3.2	3s3nA-5tkyA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_B_TPVB100_2 (HIV-1 PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.95A	3spkB-5tkyA: undetectable	3spkB-5tkyA: 11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_A_CHDA1502_0 (FERROCHELATASE, MITOCHONDRIAL)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 267 PHE A 297 LEU A 257 ILE A 301 SER A 258	None	1.15A	3w1wA-5tkyA: undetectable	3w1wA-5tkyA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJU_A_TPVA500_1 (PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.86A	4njuA-5tkyA: undetectable	4njuA-5tkyA: 10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJU_C_TPVC500_1 (PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.86A	4njuC-5tkyA: undetectable	4njuC-5tkyA: 10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGH_B_SAMB401_0 (CAFFEIC ACID O-METHYLTRANSFERASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	SER A 92 ASP A 236 GLY A 233 THR A 239 ASP A 203	None None None None MG A 701 ( 4.5A)	1.40A	4pghB-5tkyA: undetectable	4pghB-5tkyA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB307_1 (CHITOSANASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 7	GLU A 178 THR A 16 GLY A 15 THR A 17	MG A 701 ( 3.7A) ATP A 700 (-3.7A) ATP A 700 (-3.1A) ATP A 700 (-3.5A)	0.90A	4qwpB-5tkyA: undetectable	4qwpB-5tkyA: 17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNW_B_RTZB602_1 (CYTOCHROME P450 2D6)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 200 GLY A 342 LEU A 204 VAL A 321 PHE A 209	None ATP A 700 (-3.3A) None None None	1.13A	4wnwB-5tkyA: 0.0	4wnwB-5tkyA: 23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XPB_A_COCA702_1 (TRANSPORTER)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 10	ASP A 392 VAL A 29 TYR A 24 GLY A 187 GLY A 376	None	1.43A	4xpbA-5tkyA: 2.2	4xpbA-5tkyA: 21.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_A_ADNA1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	7 / 10	GLY A 205 LYS A 275 SER A 279 GLY A 343 SER A 344 ARG A 346 ILE A 347	ATP A 700 (-3.5A) ATP A 700 (-2.3A) ATP A 700 (-2.6A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A) ATP A 700 (-4.8A)	1.14A	5aqfA-5tkyA: 48.1	5aqfA-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_A_ADNA1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	10 / 10	GLY A 206 GLY A 234 GLU A 272 LYS A 275 ARG A 276 SER A 279 GLY A 343 SER A 344 ARG A 346 ILE A 347	ATP A 700 (-3.5A) ATP A 700 ( 4.4A) ATP A 700 (-4.1A) ATP A 700 (-2.3A) ATP A 700 (-3.4A) ATP A 700 (-2.6A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A) ATP A 700 (-4.8A)	0.62A	5aqfA-5tkyA: 48.1	5aqfA-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_A_ADNA1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	6 / 10	GLY A 233 GLY A 234 LYS A 275 SER A 279 SER A 344 ILE A 347	None ATP A 700 ( 4.4A) ATP A 700 (-2.3A) ATP A 700 (-2.6A) None ATP A 700 (-4.8A)	1.38A	5aqfA-5tkyA: 48.1	5aqfA-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_A_ADNA1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	6 / 10	GLY A 234 GLU A 272 ARG A 276 GLY A 343 SER A 344 ARG A 346	ATP A 700 ( 4.4A) ATP A 700 (-4.1A) ATP A 700 (-3.4A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A)	1.25A	5aqfA-5tkyA: 48.1	5aqfA-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_C_ADNC1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	7 / 10	GLY A 205 LYS A 275 SER A 279 GLY A 343 SER A 344 ARG A 346 ILE A 347	ATP A 700 (-3.5A) ATP A 700 (-2.3A) ATP A 700 (-2.6A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A) ATP A 700 (-4.8A)	1.16A	5aqfC-5tkyA: 48.0	5aqfC-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_C_ADNC1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	10 / 10	GLY A 206 GLY A 234 GLU A 272 LYS A 275 ARG A 276 SER A 279 GLY A 343 SER A 344 ARG A 346 ILE A 347	ATP A 700 (-3.5A) ATP A 700 ( 4.4A) ATP A 700 (-4.1A) ATP A 700 (-2.3A) ATP A 700 (-3.4A) ATP A 700 (-2.6A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A) ATP A 700 (-4.8A)	0.64A	5aqfC-5tkyA: 48.0	5aqfC-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_C_ADNC1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	6 / 10	GLY A 233 GLY A 234 LYS A 275 SER A 279 SER A 344 ILE A 347	None ATP A 700 ( 4.4A) ATP A 700 (-2.3A) ATP A 700 (-2.6A) None ATP A 700 (-4.8A)	1.38A	5aqfC-5tkyA: 48.0	5aqfC-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQF_C_ADNC1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	6 / 10	GLY A 234 GLU A 272 ARG A 276 GLY A 343 SER A 344 ARG A 346	ATP A 700 ( 4.4A) ATP A 700 (-4.1A) ATP A 700 (-3.4A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A)	1.27A	5aqfC-5tkyA: 48.0	5aqfC-5tkyA: 68.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQY_A_ADNA1389_1 (HEAT SHOCK 70 KDA PROTEIN 1A)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	8 / 10	GLY A 205 LYS A 275 ARG A 276 SER A 279 GLY A 343 SER A 344 ARG A 346 ILE A 347	ATP A 700 (-3.5A) ATP A 700 (-2.3A) ATP A 700 (-3.4A) ATP A 700 (-2.6A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A) ATP A 700 (-4.8A)	1.15A	5aqyA-5tkyA: 50.3	5aqyA-5tkyA: 43.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQY_A_ADNA1389_1 (HEAT SHOCK 70 KDA PROTEIN 1A)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	10 / 10	GLY A 206 GLY A 234 GLU A 272 LYS A 275 ARG A 276 SER A 279 GLY A 343 SER A 344 ARG A 346 ILE A 347	ATP A 700 (-3.5A) ATP A 700 ( 4.4A) ATP A 700 (-4.1A) ATP A 700 (-2.3A) ATP A 700 (-3.4A) ATP A 700 (-2.6A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A) ATP A 700 (-4.8A)	0.57A	5aqyA-5tkyA: 50.3	5aqyA-5tkyA: 43.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQY_A_ADNA1389_1 (HEAT SHOCK 70 KDA PROTEIN 1A)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	6 / 10	GLY A 233 GLY A 234 LYS A 275 SER A 279 SER A 344 ILE A 347	None ATP A 700 ( 4.4A) ATP A 700 (-2.3A) ATP A 700 (-2.6A) None ATP A 700 (-4.8A)	1.39A	5aqyA-5tkyA: 50.3	5aqyA-5tkyA: 43.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AQY_A_ADNA1389_1 (HEAT SHOCK 70 KDA PROTEIN 1A)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	6 / 10	GLY A 234 GLU A 272 ARG A 276 GLY A 343 SER A 344 ARG A 346	ATP A 700 ( 4.4A) ATP A 700 (-4.1A) ATP A 700 (-3.4A) ATP A 700 (-3.3A) None ATP A 700 (-4.5A)	1.25A	5aqyA-5tkyA: 50.3	5aqyA-5tkyA: 43.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_D_PAUD601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 8	ALA A 416 GLY A 407 SER A 405 GLY A 450	None	0.84A	5e26C-5tkyA: 13.0 5e26D-5tkyA: 13.0	5e26C-5tkyA: 21.95 5e26D-5tkyA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JCN_B_ASCB502_0 (OS09G0567300 PROTEIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 6	GLU A 319 PRO A 320 GLY A 316 PHE A 209	None	1.30A	5jcnB-5tkyA: undetectable	5jcnB-5tkyA: 23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M50_B_TA1B502_1 (TUBULIN BETA-2B CHAIN)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	VAL A 324 ASP A 327 SER A 212 PRO A 403 ARG A 421	None	1.46A	5m50B-5tkyA: undetectable	5m50B-5tkyA: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AWO_A_SREA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 9	ASP A 155 ALA A 509 ILE A 508 GLY A 513 GLY A 462	None	1.26A	6awoA-5tkyA: undetectable	6awoA-5tkyA: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AWQ_A_SREA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 9	ASP A 155 ALA A 509 ILE A 508 GLY A 513 GLY A 462	None	1.27A	6awqA-5tkyA: undetectable	6awqA-5tkyA: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BM5_A_SAMA1301_0 (METHIONINE SYNTHASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 11	PRO A 84 PRO A 403 PRO A 150 ALA A 151 TYR A 152	None	1.31A	6bm5A-5tkyA: undetectable	6bm5A-5tkyA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DIL_B_TPVB201_0 (HIV-1 PROTEASE)	5tky	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 14 ASP A 370 VAL A 373 GLY A 205 PRO A 150	None None None ATP A 700 (-3.5A) None	0.82A	6dilA-5tkyA: undetectable	6dilA-5tkyA: 10.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A29_A_TFPA154_1","CALMODULIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"GLU A 121;ALA A 124;LEU A 515;GLU A 519;GLU A 521","None","1.38A","1a29A-5tkyA:undetectable","1a29A-5tkyA:14.93"],["1D4S_A_TPVA201_1","PROTEIN (HIV-1 PROTEASE)","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.84A","1d4sA-5tkyA:undetectable","1d4sA-5tkyA:11.19"],["1MXG_A_ACRA442_1","ALPHA AMYLASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"GLY A 207;GLY A 234;GLN A 235;GLY A 342;ASP A 203","ATP A 700 (-3.6A);ATP A 700 ( 4.4A);None;ATP A 700 (-3.3A); MG A 701 ( 4.5A)","1.08A","1mxgA-5tkyA:undetectable","1mxgA-5tkyA:21.87"],["2PO5_A_CHDA501_0","FERROCHELATASE, MITOCHONDRIAL","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A 267;PHE A 297;LEU A 257;ILE A 301;SER A 258","None","1.07A","2po5A-5tkyA:undetectable","2po5A-5tkyA:19.65"],["2Q6O_B_SAMB500_0","HYPOTHETICAL PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"ASP A 203;VAL A 341;PRO A 150;THR A 148"," MG A 701 ( 4.5A);None;None;None","1.38A","2q6oB-5tkyA:undetectable","2q6oB-5tkyA:19.55"],["2R2V_D_ACTD37_0","GCN4 LEUCINE ZIPPER","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",3,"LYS A 604;ARG A 553;VAL A 554","None","1.01A","2r2vC-5tkyA:undetectable;2r2vD-5tkyA:undetectable","2r2vC-5tkyA:4.35;2r2vD-5tkyA:4.35"],["2V3K_A_SAMA1254_0","ESSENTIAL FOR MITOTIC GROWTH 1","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A 257;GLY A 259;LEU A 291;SER A 290;ALA A 263","None","0.71A","2v3kA-5tkyA:undetectable","2v3kA-5tkyA:17.82"],["2XRZ_A_ACTA1470_0","DEOXYRIBODIPYRIMIDINE PHOTOLYASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"ARG A 349;ALA A 311;ASP A 308;GLU A 307","None","1.37A","2xrzA-5tkyA:undetectable","2xrzA-5tkyA:21.97"],["3CYW_A_017A201_1","HIV-1 PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.78A","3cywA-5tkyA:undetectable","3cywA-5tkyA:10.45"],["3D20_A_017A201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.89A","3d20B-5tkyA:undetectable","3d20B-5tkyA:9.34"],["3EKT_D_017D200_2","PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.86A","3ektD-5tkyA:undetectable","3ektD-5tkyA:10.14"],["3KP6_B_SALB3006_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"ASN A 454;ILE A 414;GLU A 456;ASN A 458","None","1.38A","3kp6A-5tkyA:0.3;3kp6B-5tkyA:undetectable","3kp6A-5tkyA:14.29;3kp6B-5tkyA:14.29"],["3LZS_A_017A200_2","HIV-1 PROTEASE;HIV-1 PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.90A","3lzsB-5tkyA:undetectable","3lzsB-5tkyA:11.83"],["3LZU_A_017A200_1","HIV-1 PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.87A","3lzuA-5tkyA:undetectable","3lzuA-5tkyA:12.02"],["3OXX_A_DR7A100_1","HIV-1 PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.86A","3oxxA-5tkyA:undetectable","3oxxA-5tkyA:12.21"],["3R9S_C_BEZC264_0","CARNITINYL-COA DEHYDRATASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"ALA A 582;ILE A 551;LEU A 547;ALA A 602","None","0.81A","3r9sC-5tkyA:undetectable","3r9sC-5tkyA:19.55"],["3S3M_A_DLUA398_1","PFV INTEGRASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"ASP A 210;GLY A 228;TYR A 202;GLU A 178","None;None;None; MG A 701 ( 3.7A)","0.90A","3s3mA-5tkyA:3.5","3s3mA-5tkyA:20.16"],["3S3N_A_DLUA398_1","PFV INTEGRASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"ASP A 210;GLY A 228;TYR A 202;GLU A 178","None;None;None; MG A 701 ( 3.7A)","0.91A","3s3nA-5tkyA:3.2","3s3nA-5tkyA:20.16"],["3SPK_B_TPVB100_2","HIV-1 PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.95A","3spkB-5tkyA:undetectable","3spkB-5tkyA:11.01"],["3W1W_A_CHDA1502_0","FERROCHELATASE, MITOCHONDRIAL","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A 267;PHE A 297;LEU A 257;ILE A 301;SER A 258","None","1.15A","3w1wA-5tkyA:undetectable","3w1wA-5tkyA:20.75"],["4NJU_A_TPVA500_1","PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.86A","4njuA-5tkyA:undetectable","4njuA-5tkyA:10.66"],["4NJU_C_TPVC500_1","PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.86A","4njuC-5tkyA:undetectable","4njuC-5tkyA:10.66"],["4PGH_B_SAMB401_0","CAFFEIC ACID O-METHYLTRANSFERASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"SER A  92;ASP A 236;GLY A 233;THR A 239;ASP A 203","None;None;None;None; MG A 701 ( 4.5A)","1.40A","4pghB-5tkyA:undetectable","4pghB-5tkyA:21.38"],["4QWP_B_GCSB307_1","CHITOSANASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"GLU A 178;THR A  16;GLY A  15;THR A  17"," MG A 701 ( 3.7A);ATP A 700 (-3.7A);ATP A 700 (-3.1A);ATP A 700 (-3.5A)","0.90A","4qwpB-5tkyA:undetectable","4qwpB-5tkyA:17.63"],["4WNW_B_RTZB602_1","CYTOCHROME P450 2D6","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A 200;GLY A 342;LEU A 204;VAL A 321;PHE A 209","None;ATP A 700 (-3.3A);None;None;None","1.13A","4wnwB-5tkyA:0.0","4wnwB-5tkyA:23.48"],["4XPB_A_COCA702_1","TRANSPORTER","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"ASP A 392;VAL A  29;TYR A  24;GLY A 187;GLY A 376","None","1.43A","4xpbA-5tkyA:2.2","4xpbA-5tkyA:21.81"],["5AQF_A_ADNA1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",7,"GLY A 205;LYS A 275;SER A 279;GLY A 343;SER A 344;ARG A 346;ILE A 347","ATP A 700 (-3.5A);ATP A 700 (-2.3A);ATP A 700 (-2.6A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A);ATP A 700 (-4.8A)","1.14A","5aqfA-5tkyA:48.1","5aqfA-5tkyA:68.03"],["5AQF_A_ADNA1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",10,"GLY A 206;GLY A 234;GLU A 272;LYS A 275;ARG A 276;SER A 279;GLY A 343;SER A 344;ARG A 346;ILE A 347","ATP A 700 (-3.5A);ATP A 700 ( 4.4A);ATP A 700 (-4.1A);ATP A 700 (-2.3A);ATP A 700 (-3.4A);ATP A 700 (-2.6A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A);ATP A 700 (-4.8A)","0.62A","5aqfA-5tkyA:48.1","5aqfA-5tkyA:68.03"],["5AQF_A_ADNA1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",6,"GLY A 233;GLY A 234;LYS A 275;SER A 279;SER A 344;ILE A 347","None;ATP A 700 ( 4.4A);ATP A 700 (-2.3A);ATP A 700 (-2.6A);None;ATP A 700 (-4.8A)","1.38A","5aqfA-5tkyA:48.1","5aqfA-5tkyA:68.03"],["5AQF_A_ADNA1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",6,"GLY A 234;GLU A 272;ARG A 276;GLY A 343;SER A 344;ARG A 346","ATP A 700 ( 4.4A);ATP A 700 (-4.1A);ATP A 700 (-3.4A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A)","1.25A","5aqfA-5tkyA:48.1","5aqfA-5tkyA:68.03"],["5AQF_C_ADNC1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",7,"GLY A 205;LYS A 275;SER A 279;GLY A 343;SER A 344;ARG A 346;ILE A 347","ATP A 700 (-3.5A);ATP A 700 (-2.3A);ATP A 700 (-2.6A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A);ATP A 700 (-4.8A)","1.16A","5aqfC-5tkyA:48.0","5aqfC-5tkyA:68.03"],["5AQF_C_ADNC1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",10,"GLY A 206;GLY A 234;GLU A 272;LYS A 275;ARG A 276;SER A 279;GLY A 343;SER A 344;ARG A 346;ILE A 347","ATP A 700 (-3.5A);ATP A 700 ( 4.4A);ATP A 700 (-4.1A);ATP A 700 (-2.3A);ATP A 700 (-3.4A);ATP A 700 (-2.6A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A);ATP A 700 (-4.8A)","0.64A","5aqfC-5tkyA:48.0","5aqfC-5tkyA:68.03"],["5AQF_C_ADNC1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",6,"GLY A 233;GLY A 234;LYS A 275;SER A 279;SER A 344;ILE A 347","None;ATP A 700 ( 4.4A);ATP A 700 (-2.3A);ATP A 700 (-2.6A);None;ATP A 700 (-4.8A)","1.38A","5aqfC-5tkyA:48.0","5aqfC-5tkyA:68.03"],["5AQF_C_ADNC1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",6,"GLY A 234;GLU A 272;ARG A 276;GLY A 343;SER A 344;ARG A 346","ATP A 700 ( 4.4A);ATP A 700 (-4.1A);ATP A 700 (-3.4A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A)","1.27A","5aqfC-5tkyA:48.0","5aqfC-5tkyA:68.03"],["5AQY_A_ADNA1389_1","HEAT SHOCK 70 KDA PROTEIN 1A","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",8,"GLY A 205;LYS A 275;ARG A 276;SER A 279;GLY A 343;SER A 344;ARG A 346;ILE A 347","ATP A 700 (-3.5A);ATP A 700 (-2.3A);ATP A 700 (-3.4A);ATP A 700 (-2.6A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A);ATP A 700 (-4.8A)","1.15A","5aqyA-5tkyA:50.3","5aqyA-5tkyA:43.32"],["5AQY_A_ADNA1389_1","HEAT SHOCK 70 KDA PROTEIN 1A","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",10,"GLY A 206;GLY A 234;GLU A 272;LYS A 275;ARG A 276;SER A 279;GLY A 343;SER A 344;ARG A 346;ILE A 347","ATP A 700 (-3.5A);ATP A 700 ( 4.4A);ATP A 700 (-4.1A);ATP A 700 (-2.3A);ATP A 700 (-3.4A);ATP A 700 (-2.6A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A);ATP A 700 (-4.8A)","0.57A","5aqyA-5tkyA:50.3","5aqyA-5tkyA:43.32"],["5AQY_A_ADNA1389_1","HEAT SHOCK 70 KDA PROTEIN 1A","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",6,"GLY A 233;GLY A 234;LYS A 275;SER A 279;SER A 344;ILE A 347","None;ATP A 700 ( 4.4A);ATP A 700 (-2.3A);ATP A 700 (-2.6A);None;ATP A 700 (-4.8A)","1.39A","5aqyA-5tkyA:50.3","5aqyA-5tkyA:43.32"],["5AQY_A_ADNA1389_1","HEAT SHOCK 70 KDA PROTEIN 1A","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",6,"GLY A 234;GLU A 272;ARG A 276;GLY A 343;SER A 344;ARG A 346","ATP A 700 ( 4.4A);ATP A 700 (-4.1A);ATP A 700 (-3.4A);ATP A 700 (-3.3A);None;ATP A 700 (-4.5A)","1.25A","5aqyA-5tkyA:50.3","5aqyA-5tkyA:43.32"],["5E26_D_PAUD601_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"ALA A 416;GLY A 407;SER A 405;GLY A 450","None","0.84A","5e26C-5tkyA:13.0;5e26D-5tkyA:13.0","5e26C-5tkyA:21.95;5e26D-5tkyA:21.95"],["5JCN_B_ASCB502_0","OS09G0567300 PROTEIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"GLU A 319;PRO A 320;GLY A 316;PHE A 209","None","1.30A","5jcnB-5tkyA:undetectable","5jcnB-5tkyA:23.70"],["5M50_B_TA1B502_1","TUBULIN BETA-2B CHAIN","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"VAL A 324;ASP A 327;SER A 212;PRO A 403;ARG A 421","None","1.46A","5m50B-5tkyA:undetectable","5m50B-5tkyA:21.34"],["6AWO_A_SREA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"ASP A 155;ALA A 509;ILE A 508;GLY A 513;GLY A 462","None","1.26A","6awoA-5tkyA:undetectable","6awoA-5tkyA:21.83"],["6AWQ_A_SREA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"ASP A 155;ALA A 509;ILE A 508;GLY A 513;GLY A 462","None","1.27A","6awqA-5tkyA:undetectable","6awqA-5tkyA:21.83"],["6BM5_A_SAMA1301_0","METHIONINE SYNTHASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"PRO A  84;PRO A 403;PRO A 150;ALA A 151;TYR A 152","None","1.31A","6bm5A-5tkyA:undetectable","6bm5A-5tkyA:19.90"],["6DIL_B_TPVB201_0","HIV-1 PROTEASE","5tky","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU A  14;ASP A 370;VAL A 373;GLY A 205;PRO A 150","None;None;None;ATP A 700 (-3.5A);None","0.82A","6dilA-5tkyA:undetectable","6dilA-5tkyA:10.34"]]