SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KNY_B_KANB559_1 (KANAMYCIN NUCLEOTIDYLTRANSFERA SE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	4 / 8	GLU D 44 SER D 62 ASP D 61 GLU D 46	None	1.05A	1knyA-5tokD: undetectable 1knyB-5tokD: undetectable	1knyA-5tokD: 17.00 1knyB-5tokD: 17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_A_SAMA601_0 (NS5 METHYLTRANSFERASE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	5 / 12	GLY D 100 GLY D 35 GLY D 100 VAL D 78 ILE D 51	None	1.00A	5wz1A-5tokD: undetectable	5wz1A-5tokD: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_C_SAMC601_0 (NS5 METHYLTRANSFERASE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	5 / 12	GLY D 100 GLY D 35 GLY D 100 VAL D 78 ILE D 51	None	1.01A	5wz1C-5tokD: undetectable	5wz1C-5tokD: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_D_SAMD601_0 (NS5 METHYLTRANSFERASE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	5 / 12	GLY D 100 GLY D 35 GLY D 100 VAL D 78 ILE D 51	None	1.03A	5wz1D-5tokD: undetectable	5wz1D-5tokD: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_E_SAME601_0 (NS5 METHYLTRANSFERASE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	5 / 12	GLY D 100 GLY D 35 GLY D 100 VAL D 78 ILE D 51	None	1.00A	5wz1E-5tokD: undetectable	5wz1E-5tokD: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_F_SAMF601_0 (NS5 METHYLTRANSFERASE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	5 / 12	GLY D 100 GLY D 35 GLY D 100 VAL D 78 ILE D 51	None	1.01A	5wz1F-5tokD: undetectable	5wz1F-5tokD: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_G_SAMG601_0 (NS5 METHYLTRANSFERASE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	5 / 12	GLY D 100 GLY D 35 GLY D 100 VAL D 78 ILE D 51	None	1.03A	5wz1G-5tokD: undetectable	5wz1G-5tokD: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_H_SAMH601_0 (NS5 METHYLTRANSFERASE)	5tok	SINGLE-DOMAIN ANTIBODY F-VHH-L66 (Lama glama)	5 / 12	GLY D 100 GLY D 35 GLY D 100 VAL D 78 ILE D 51	None	1.02A	5wz1H-5tokD: undetectable	5wz1H-5tokD: 17.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KNY_B_KANB559_1","KANAMYCIN NUCLEOTIDYLTRANSFERASE;KANAMYCIN NUCLEOTIDYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",4,"GLU D  44;SER D  62;ASP D  61;GLU D  46","None","1.05A","1knyA-5tokD:undetectable;1knyB-5tokD:undetectable","1knyA-5tokD:17.00;1knyB-5tokD:17.00"],["5WZ1_A_SAMA601_0","NS5 METHYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",5,"GLY D 100;GLY D  35;GLY D 100;VAL D  78;ILE D  51","None","1.00A","5wz1A-5tokD:undetectable","5wz1A-5tokD:17.75"],["5WZ1_C_SAMC601_0","NS5 METHYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",5,"GLY D 100;GLY D  35;GLY D 100;VAL D  78;ILE D  51","None","1.01A","5wz1C-5tokD:undetectable","5wz1C-5tokD:17.75"],["5WZ1_D_SAMD601_0","NS5 METHYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",5,"GLY D 100;GLY D  35;GLY D 100;VAL D  78;ILE D  51","None","1.03A","5wz1D-5tokD:undetectable","5wz1D-5tokD:17.75"],["5WZ1_E_SAME601_0","NS5 METHYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",5,"GLY D 100;GLY D  35;GLY D 100;VAL D  78;ILE D  51","None","1.00A","5wz1E-5tokD:undetectable","5wz1E-5tokD:17.75"],["5WZ1_F_SAMF601_0","NS5 METHYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",5,"GLY D 100;GLY D  35;GLY D 100;VAL D  78;ILE D  51","None","1.01A","5wz1F-5tokD:undetectable","5wz1F-5tokD:17.75"],["5WZ1_G_SAMG601_0","NS5 METHYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",5,"GLY D 100;GLY D  35;GLY D 100;VAL D  78;ILE D  51","None","1.03A","5wz1G-5tokD:undetectable","5wz1G-5tokD:17.75"],["5WZ1_H_SAMH601_0","NS5 METHYLTRANSFERASE","5tok","SINGLE-DOMAIN ANTIBODY F-VHH-L66","Lama glama",5,"GLY D 100;GLY D  35;GLY D 100;VAL D  78;ILE D  51","None","1.02A","5wz1H-5tokD:undetectable","5wz1H-5tokD:17.75"]]