SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 5tou PHYCOCYANIN BETA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		5 / 11 ALA D 140
LEU D 105
ASP D 165
GLY D 161
ALA D 168
 None
 1.11A 1b02A-5touD:
undetectable		 1b02A-5touD:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5tou PHYCOCYANIN BETA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		4 / 5 TYR D 163
VAL D  52
ILE D 131
MET D 157
 None
 1.27A 1opjA-5touD:
undetectable		 1opjA-5touD:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5tou PHYCOCYANIN ALPHA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		3 / 3 GLU C   7
ASP C 108
TYR C 156
 None
 0.80A 2yvlB-5touC:
undetectable		 2yvlB-5touC:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5tou PHYCOCYANIN BETA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		5 / 11 ILE D 131
LEU D  90
ALA D  55
CYH D 109
LEU D 105
 None
None
None
CYC  D 202 ( 3.9A)
None
 1.24A 5ji0A-5touD:
undetectable		 5ji0A-5touD:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5tou PHYCOCYANIN BETA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		5 / 11 ALA D 167
ALA D 169
VAL D  93
GLY D 130
GLY D 132
 None
 0.89A 5lf7K-5touD:
undetectable
5lf7L-5touD:
undetectable		 5lf7K-5touD:
26.07
5lf7L-5touD:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5tou PHYCOCYANIN BETA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		5 / 11 ALA D 169
VAL D  93
GLY D 130
GLY D 132
ASP D 165
 None
 0.88A 5lf7K-5touD:
undetectable
5lf7L-5touD:
undetectable		 5lf7K-5touD:
26.07
5lf7L-5touD:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5tou PHYCOCYANIN BETA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		5 / 11 ALA D 167
ALA D 169
VAL D  93
GLY D 130
GLY D 132
 None
 0.91A 5lf7Y-5touD:
undetectable
5lf7Z-5touD:
undetectable		 5lf7Y-5touD:
26.07
5lf7Z-5touD:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5tou PHYCOCYANIN BETA-1
SUBUNIT
(Pseudanabaena
sp.
lw0831) 		5 / 11 ALA D 169
VAL D  93
GLY D 130
GLY D 132
ASP D 165
 None
 0.90A 5lf7Y-5touD:
undetectable
5lf7Z-5touD:
undetectable		 5lf7Y-5touD:
26.07
5lf7Z-5touD:
19.09