SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KNY_A_KANA558_1 (KANAMYCIN NUCLEOTIDYLTRANSFERA SE)	5tp3	F-VHH-4 (Lama glama)	4 / 7	SER A 62 ASP A 61 GLU A 46 GLU A 44	None	0.83A	1knyA-5tp3A: undetectable 1knyB-5tp3A: undetectable	1knyA-5tp3A: 17.67 1knyB-5tp3A: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KNY_B_KANB559_1 (KANAMYCIN NUCLEOTIDYLTRANSFERA SE)	5tp3	F-VHH-4 (Lama glama)	4 / 8	GLU A 44 SER A 62 ASP A 61 GLU A 46	None	0.92A	1knyA-5tp3A: undetectable 1knyB-5tp3A: undetectable	1knyA-5tp3A: 17.67 1knyB-5tp3A: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1424_0 (FPRA)	5tp3	F-VHH-4 (Lama glama)	4 / 4	ALA A 88 ARG A 38 GLN A 39 GLU A 46	None	1.34A	1lquB-5tp3A: undetectable	1lquB-5tp3A: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5tp3	F-VHH-4 (Lama glama)	4 / 7	ALA A 88 THR A 87 VAL A 109 GLU A 85	None	0.76A	5ecmD-5tp3A: undetectable	5ecmD-5tp3A: 12.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KNY_A_KANA558_1","KANAMYCIN NUCLEOTIDYLTRANSFERASE;KANAMYCIN NUCLEOTIDYLTRANSFERASE","5tp3","F-VHH-4","Lama glama",4,"SER A  62;ASP A  61;GLU A  46;GLU A  44","None","0.83A","1knyA-5tp3A:undetectable;1knyB-5tp3A:undetectable","1knyA-5tp3A:17.67;1knyB-5tp3A:17.67"],["1KNY_B_KANB559_1","KANAMYCIN NUCLEOTIDYLTRANSFERASE;KANAMYCIN NUCLEOTIDYLTRANSFERASE","5tp3","F-VHH-4","Lama glama",4,"GLU A  44;SER A  62;ASP A  61;GLU A  46","None","0.92A","1knyA-5tp3A:undetectable;1knyB-5tp3A:undetectable","1knyA-5tp3A:17.67;1knyB-5tp3A:17.67"],["1LQU_B_ACTB1424_0","FPRA","5tp3","F-VHH-4","Lama glama",4,"ALA A  88;ARG A  38;GLN A  39;GLU A  46","None","1.34A","1lquB-5tp3A:undetectable","1lquB-5tp3A:13.23"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5tp3","F-VHH-4","Lama glama",4,"ALA A  88;THR A  87;VAL A 109;GLU A  85","None","0.76A","5ecmD-5tp3A:undetectable","5ecmD-5tp3A:12.61"]]