SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ALA A 356
GLY A 355
HIS A 358
HIS A 190
ASP A  95
 MES  A 503 (-3.7A)
None
None
ZN  A 501 (-3.6A)
ZN  A 502 ( 4.1A)
 1.47A 1a4lD-5tp4A:
undetectable		 1a4lD-5tp4A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 9 GLY A  96
TYR A 186
ILE A 361
HIS A 358
GLY A 357
 ZN  A 501 (-3.9A)
None
EDO  A 504 ( 4.2A)
None
MES  A 503 (-3.9A)
 1.29A 1acjA-5tp4A:
2.2		 1acjA-5tp4A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.01A 1cqeA-5tp4A:
undetectable		 1cqeA-5tp4A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.02A 1cqeB-5tp4A:
undetectable		 1cqeB-5tp4A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 11 ALA A  47
VAL A  57
MET A  55
VAL A 107
LEU A  80
 None
 1.09A 1n4hA-5tp4A:
undetectable		 1n4hA-5tp4A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 7 ARG A  93
VAL A  97
LEU A 101
ALA A  20
 EDO  A 506 (-3.6A)
None
None
EDO  A 506 ( 4.9A)
 0.88A 1pthA-5tp4A:
undetectable		 1pthA-5tp4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 7 ARG A  93
VAL A  97
LEU A 101
ALA A  20
 EDO  A 506 (-3.6A)
None
None
EDO  A 506 ( 4.9A)
 0.87A 1pthB-5tp4A:
undetectable		 1pthB-5tp4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 6 LEU A 139
PHE A 134
ALA A 135
LEU A 148
 None
None
FMT  A 511 ( 4.5A)
None
 0.97A 1ukbA-5tp4A:
2.7		 1ukbA-5tp4A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 8 ASP A 184
LYS A 119
GLY A  71
THR A  56
 None
None
None
EDO  A 507 (-4.2A)
 0.93A 2aouA-5tp4A:
undetectable		 2aouA-5tp4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.10A 2aylA-5tp4A:
0.5		 2aylA-5tp4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 THR A 117
VAL A 183
ALA A 185
ALA A  76
ILE A  81
 None
 1.28A 3dl9B-5tp4A:
undetectable		 3dl9B-5tp4A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 5 THR A 117
VAL A 410
GLY A 409
LYS A 119
 None
 0.89A 3elzA-5tp4A:
undetectable		 3elzA-5tp4A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		6 / 12 GLY A  63
ASN A  64
GLY A 146
ALA A 147
GLY A 140
LEU A 139
 None
 1.09A 3hs6B-5tp4A:
undetectable		 3hs6B-5tp4A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.00A 3n8zA-5tp4A:
undetectable		 3n8zA-5tp4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 0.95A 3n8zB-5tp4A:
undetectable		 3n8zB-5tp4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.08A 3nt1A-5tp4A:
0.5		 3nt1A-5tp4A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.08A 3nt1B-5tp4A:
undetectable		 3nt1B-5tp4A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 11 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 0.98A 3pghB-5tp4A:
undetectable		 3pghB-5tp4A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 0.98A 3pghD-5tp4A:
undetectable		 3pghD-5tp4A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		3 / 3 GLU A 192
PHE A 373
GLN A 193
 None
None
ZN  A 502 (-4.3A)
 1.00A 3r55A-5tp4A:
undetectable		 3r55A-5tp4A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 8 PHE A 144
GLU A 188
TYR A 186
LEU A  80
 EDO  A 505 ( 4.9A)
None
None
None
 0.95A 3rqwC-5tp4A:
2.1
3rqwD-5tp4A:
undetectable		 3rqwC-5tp4A:
22.17
3rqwD-5tp4A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 8 PHE A 144
GLU A 188
TYR A 186
LEU A  80
 EDO  A 505 ( 4.9A)
None
None
None
 0.93A 3rqwI-5tp4A:
undetectable
3rqwJ-5tp4A:
undetectable		 3rqwI-5tp4A:
22.17
3rqwJ-5tp4A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 8 GLU A 188
TYR A 186
LEU A  80
PHE A 144
 None
None
None
EDO  A 505 ( 4.9A)
 0.90A 3rqwF-5tp4A:
undetectable
3rqwJ-5tp4A:
undetectable		 3rqwF-5tp4A:
22.17
3rqwJ-5tp4A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.10A 3rr3C-5tp4A:
undetectable		 3rr3C-5tp4A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.09A 3rr3D-5tp4A:
undetectable		 3rr3D-5tp4A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 9 GLY A  54
ALA A  53
ASP A  52
LEU A 121
VAL A 107
 None
 0.98A 3u7sB-5tp4A:
undetectable		 3u7sB-5tp4A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ASN A  64
GLY A 146
ALA A 147
GLY A 140
LEU A 139
 None
 1.05A 4e1gA-5tp4A:
undetectable		 4e1gA-5tp4A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.02A 4m11A-5tp4A:
undetectable		 4m11A-5tp4A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.07A 4m11D-5tp4A:
undetectable		 4m11D-5tp4A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		3 / 3 GLU A 122
ALA A  67
PHE A  66
 EDO  A 505 (-2.7A)
None
EDO  A 505 ( 4.3A)
 0.66A 4v1fA-5tp4A:
undetectable		 4v1fA-5tp4A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		3 / 3 GLU A 122
ALA A  67
PHE A  66
 EDO  A 505 (-2.7A)
None
EDO  A 505 ( 4.3A)
 0.67A 4v1fC-5tp4A:
undetectable		 4v1fC-5tp4A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 10 ASP A  60
ASN A  64
VAL A  62
LEU A  35
ALA A  34
 None
 1.48A 4yhaB-5tp4A:
undetectable		 4yhaB-5tp4A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 4 LEU A 363
LEU A  80
GLY A  82
GLU A 188
 None
 1.04A 5hhjA-5tp4A:
undetectable		 5hhjA-5tp4A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.09A 5ikqA-5tp4A:
undetectable		 5ikqA-5tp4A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.12A 5ikqB-5tp4A:
undetectable		 5ikqB-5tp4A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.11A 5ikrA-5tp4A:
undetectable		 5ikrA-5tp4A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.09A 5jvzA-5tp4A:
undetectable		 5jvzA-5tp4A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ARG A  93
VAL A  97
LEU A 101
TRP A  49
ALA A  20
 EDO  A 506 (-3.6A)
None
None
None
EDO  A 506 ( 4.9A)
 1.11A 5jvzB-5tp4A:
undetectable		 5jvzB-5tp4A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		4 / 4 THR A  36
ASP A  39
ARG A  32
LEU A  33
 None
 1.37A 5tdmA-5tp4A:
1.8		 5tdmA-5tp4A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ILE A  81
VAL A 399
ILE A   7
LEU A 110
THR A 109
 None
 1.18A 5tiwB-5tp4A:
undetectable		 5tiwB-5tp4A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Burkholderia
ambifaria) 		5 / 12 ALA A  72
GLY A 114
ALA A 113
LEU A 401
LEU A 405
 None
 1.17A 5x23A-5tp4A:
undetectable		 5x23A-5tp4A:
20.97