SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tpi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA888_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 5tpi PUTATIVE
TRANSCRIPTIONAL
REGULATOR (LYSR
FAMILY)
(Klebsiella
pneumoniae) 		4 / 5 PRO A 235
MET A 238
ALA A 101
GLU A  97
 None
 1.25A 1qhsA-5tpiA:
undetectable		 1qhsA-5tpiA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5tpi PUTATIVE
TRANSCRIPTIONAL
REGULATOR (LYSR
FAMILY)
(Klebsiella
pneumoniae) 		4 / 6 PRO A 235
MET A 238
ALA A 101
GLU A  97
 None
 1.47A 1qhyA-5tpiA:
undetectable		 1qhyA-5tpiA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5tpi PUTATIVE
TRANSCRIPTIONAL
REGULATOR (LYSR
FAMILY)
(Klebsiella
pneumoniae) 		5 / 12 ILE A 279
ARG A 286
LEU A 282
LEU A 122
LEU A  93
 None
 1.43A 4qynB-5tpiA:
undetectable		 4qynB-5tpiA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5tpi PUTATIVE
TRANSCRIPTIONAL
REGULATOR (LYSR
FAMILY)
(Klebsiella
pneumoniae) 		3 / 3 SER A  98
TYR A 218
ASP A 145
 CL  A 301 (-2.9A)
CL  A 301 (-4.9A)
None
 0.69A 4rp8C-5tpiA:
undetectable		 4rp8C-5tpiA:
18.49